Sep 24, 2018 | insightscare |
www.insightscare.com July 2018 SELF CARE CATALYSTS Transforming Healthcare through Real World Evidence and Experience 1 T 0 he Most INNO VAT IVE DIGITAL HEALTHCARE SOLUTION PROVIDERS 2018 Grace Castillo-Soyao Founder &CEO Chrissa McFarlane CEO & Founder Patientory, Inc. Helping allpeople live healthy lives w w w .b d .c o m Healthcare www.usa.philips.com From the Editor igital healthcare is the buzz word these days. Technologies like Artificial Intelligence, Machine Learning, BigData DAnalytics, and more have the potential to revolutionize the medical sector. These innovative digital technologies can play a pivotal role in curbing long term healthcare costs, and enabling better health outcomes. Digital healthcare can empower both the patient and healthcare provider with real-time data and assist in far better healthcare outcomes. Mobile phones, smartphone sensors, wearable gadgets, cloud storage, and big data can assist healthcare providers and patients in the early detection of various chronic diseases. With the efficient and precise use of these technologies, behavioral changes could be detected in early stages which prevent, eliminate or reduce the overall healthcare cost. Patients will also get empowered with the usage of these technologies. Patients will be able to compare the service, quality and affordability of different healthcare providers and thus assist in making an informed decision based on value, which will ultimately improve productivity. Telemedicine and remote monitoring are the other facets of digital healthcare which can improve patient's health without even directly coming to the hospital premises and ensures the most efficient level of care through long distance. These benefits are driving the digital healthcare innovations towards the positive trajectory. In 2016, the global digital health market was valued at $179.6 billion and is expected to touch $536.6 billion by the end of 2025. The projected CAGR of 13.4% from 2017 to 2025 itself indicate the growing interest of technology adoption in healthcare. But there are certain areas that need an overhaul. The digital environment comes with an array of implications, and evolving will require a bit of a balancing act. For example, products will need to be "patient differentiated" while delivering both value and best-in-class quality, and solutions. Digital healthcare solutions will need to cover a broader part of the patient pathway supporting the full range of care. Apps and devices must be secure yet provide seamless interoperability, and the value proposition must be transparent while driving improvements across the value chain. Better usage of big data analytics and machine learning algorithms to draw much more effective insights without any error is the other area which must be looked into on priority basis. Working on these vital aspects will truly transform healthcare vertical and will provide the optimum level of benefits to all the stakeholders. Convergence of Life Sciences and Technology can Revolutionize the Healthcare Vertical Ashwini Deshmukh Insights Success Media Tech LLC 555 Metro Place North, Suite 100, Dublin, OH 43017, United States Phone - (614)-602-1754 Email: firstname.lastname@example.org For Subscription: www.insightscare.com Insights Success Media and Technology Pvt.Ltd. Of ce No. 510, 513, 5th Floor, Rainbow Plaza, Shivar Chowk, Pimple Saudagar, Pune, Maharashtra 411017 Phone - India: 7410033802, 74100058552 Email: email@example.com For Subscription: www.insightscare.com firstname.lastname@example.org July, 2018 Corporate Of ces: Editor-in-Chief Pooja M. Bansal Managing Editor Ashwini Deshmukh Executive Editor Shane Gomez Visualiser David King Art & Design Director Amol Kamble Associate Designer RahulKavanekar Co-designer Vanshika, Shweta Art & Picture Editor Paul Belin Jayant Khanna Senior Sales Manager Amy Jones Business Development Manager Mark Williams Sales Executives Kelli Thomas, Bill Thompson, John Smith Technical Head Swapnil Patil Technical Specialist Amar, Vivek, Pratiksha Digital Marketing Manager Marry D'Souza SME-SMO Executives Prashant Chevale, Uma Dhenge Research Analyst Chidiebere Moses Circulation Manager Robert, Tanaji Database Management Stella Andrew Technology Consultant David Stokes Copyright 2018 Insights Success, All rights reserved. The content and images used in this magazine should not be reproduced or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without prior permission from Insights Success. Reprint rights remain solely with Insights Success. The Caretakersof ourHealth ood healthcare providers are good communicators. They reflect altruism through a strong sense of service for the betterment of healthcare. For such providers, patients always are at the forefront of their every operation. GThey understand the agony of underprivileged patients and thus believe in giving back to society in terms of affordable, subsidized or even free of cost healthcare services to the needy. Ace healthcare providers carry the highest degree of professionalism and work with full integrity to treat the patients. For them, earning money is never the main intention; instead, sharing the burden of the distressed patient remains the focal point of their every maneuver. Such healthcare providers always foster a healthy team environment at their workplace and engage in behaviors that benefit the team and display empathic behaviors when interacting with patients and their family members. To highlight such great healthcare providers, we have come up with an issue of "The 10 Most Innovative Digital Healthcare Solution Providers 2018". On the cover we have highlighted Self Care Catalysts. It is a cloud based analytics company powered by real world evidence to impact health decisions and outcomes of patients, physicians, providers, payer and pharmaceutical industry. Biolumo is growing MedTech Company that aims to provide the doctors with a device which helps them in making accurate antibiotic prescriptions. healthbank is a health-tech firm that provides cutting-edge solutions for managing clinical data. Intelligent Locations is focused on optimizing hospital operations and increasing patient satisfaction by implementing an easy to use Real-Time Location Services (RTLS) platform for the healthcare industry. Kanteron Systems helps healthcare providers to manage imaging and genomic data effectively, for precision medicine applications at the point of care. Marham is a digital healthcare platform assisting people to find, ask, and consult a doctor. oladoc is a healthcare startup provides a leading-edge health-tech platform that solves all challenges that come across a typical patient life-cycle. Patientory, Inc. provides an easy way to securely store and manage health information in real time. It is the leading provider of dApp and block-chain solutions for healthcare sector. Sehat Kahani is an all-female healthcare service provider which aims at providing cost-effective healthcare solutions. Sihatech is a digital healthcare company that helps in documenting a patient's medical journey as well as provides financing services to the non-insured medical treatments. We have included some intriguing piece of articles written exclusively by industry veterans and our in-house editors which you will find captivating. So, do flip the pages and enjoy reading!! DIGITAL THE 10 Mo st Innovative H E A L T H C A R E SOLUTION PROVIDERS 2018 da Vinci is powered by robotic technology that allows the surgeon's hand movements to be scaled, filtered and translated into precise movements of the EndoWrist instruments working inside the patient'sbody. The da Vinci Surgical System Self Care Catalysts: Transforming Healthcare through Real World Evidence andExperience CoverStory 10 Contents Company of theMonth Patientory Your Health atYour Fingertips 18 InventiveDiagnostic Tool Liquid Biopsy: ANon-Invasive Approach Intended for Personalized Careof CancerPatients Tech-Health Smart Inhalers:Tackling RespiratoryMaladies with IoT Insider'sOpinion MolecularGenetic Diagnostics: ABird's Eye-View Analytics in US Healthcare Expert'sViewpoint FromRelevanceto Convenience toValue The Future ofData cxo 50 30 26 42 22 24 32 Biolumo: An IngeniousSolution for Precise Antibiotic Selection healthbank: Transforming the Way Health Data getExchanged, Stored and Monetized Intelligent Locations: A Seamless SolutionProvider to all Digital Healthcare Problems 34 38 40 46 48 Kanteron Systems: An Incredible Precision Medicine andDiagnostic Platform Marham: Sharing the Distressof thoseFighting a Disease oladoc: Engineered a Groundbreaking 'Hub' to Bring VariedHealthcare Services toConsumers Sehat Kahani: Making QualityHealthcare FacilitiesAccessible and Affordable toAll Sihatech: Emboldening theConnect between Doctors and Patients GraceCastillo-Soyao Founder &CEO CoverStory Transforming Healthcare through Real World Evidence and Experience Digital Transformation will play a pivotal role in the future of Healthcare selfcare catal sts Patients are the most vital part of any healthcare eco- system. Everything starts and ends with patients. When a healthcare solution provider keeps patient at the center of their operations, chances of better patient satisfaction augment significantly. Such providers believe when patients are informed, respected, and engaged, they make better choices for maintaining healthier lifestyle. One such trailblazing healthcare solution provider is Self Care Catalysts (SCC), which considers patient's real world evidences/experiences are necessary for crafting cutting- edge healthcare solution. This Toronto headquartered organization was founded in 2010 with the mission to promote self-care behaviors among patients, while enabling patients to contribute their behavioral data to support important research across the product lifecycle, such as drug discovery, precision medicine, and development of support services and programs that are specific to the community. Today, after a successful stint of several years in the business, Self Care Catalysts is leveraging its intimate understanding of The organization's vision is to contribute towards the improvements of healthcare eco-system that are driven by patient's willingness to participate, share and own their data through research and behavior interventions. They are working towards the empowerment of patients through personalized and customized self-care tools like digital therapeutics that generate real world experiences and evidence to support better healthcare decision-making. Journey towards Excellence With the desire to craft an ecosystem that can set a landmark in the health journey of a patient, Self Care Catalysts was established. In a shorter span of time, it moved ahead with full vigor and collaborated among all stakeholders, be it patients, providers, pharmaceutical companies and doctors to seamlessly paint a full patient experience in order to manage better health outcomes. They have built a SaaS that empowers physicians, Health Storylines Creator is a customized and personalized platform that can be used for clinical research, patient monitoring, patient behavior modification, and patient support. It is a disease-agnostic, customized and personalized self-care and disease management product and tool to generate real world evidence. Patient Storylines is an enterprise platform that can run various analytics required by Pharmaceutical industry, patients and physicians. Health Storylines has been ranked #1 in motivating behavior change among heart failure patients by many eminent healthcare organizations. New Product Innovation Award for North America, Frost & Sullivan (2016) award, Springboard Enterprises' Life Sciences awards among others are few of the top notch accolades that Self Care Catalysts has earned with its sheer commitment towards designing efficient and deep impacting products. Self Care Catalysts is known for building an eco-system that generates and interprets real world patient experiences outside the traditional clinical labs or genomics data to complete the entire patient journey. And its eco-system is "We have built a SaaSthat empowers physicians, researchers, and providers to customize and personalize patient care" ( patients in the market with its many state-of- the-art solutions. It is a cloud based solutions and analytics company powered by real world evidence to impact health decisions and outcomes of patients, physicians, providers, payer and pharmaceutical industry. DIGITAL THE 10 Mo st Innovative H E A L T H C A R E SOLUTION PROVIDERS 2018 researchers, providers to customize and personalize care for patients to generate real world, real time data. The company understands the power of technology and thus always aims to be at the forefront of using leading-edge technology to craft better products. The company is aiming to extend personalized medicine to personalized healthcare through the application of AI, Behavior Science and BlockChain. Its endeavor is to build a new healthcare business model where patients, physicians, providers and industry are equal participants in research, care and healthy economic exchange. Products and Services They have multiple products and services that are widely popular in the healthcare sector and have won many accolades for the same as well. Some of its notable products are: bringing positive transformational changes towards drug development, clinical research, product commercialization, post marketing, patient monitoring, behavior care and population health management. Patients are the Most Significant Stakeholders The management has nurtured a robust company culture where the vital traits like resilience and risk taking attitude are always encouraged. For them, bigger the challenge is, more bigger is the opportunity. They never bog down with challenges rather turn them into an opportunity to grow further. Their ability to forecast changes in industry and mitigate risks are deeply rooted on their culture which always assists them to turn out with more shine even after facing a catastrophe like situation. The company is strengthening its data collection and analytics tools but most importantly, they treat the patients as the most significant stakeholder whose needs to improve outcomes and quality of life are addressed by leveraging continuous collection and interpretation of real world experiences. Judicious Leadership Over the years, Grace Castillo-Soyao has taken various executive business and leadership programs from the Rotman School of Business, University of Toronto, the Wharton School at University of Pennsylvania and has a rich corporate experience of over 20 years in pharmaceutical vertical. She is the Founder and CEO of Self Care Catalysts and is driving this organization towards the path of glory with her astute business mind and adept had wondered how drugs are approved based on a narrow ' leadership skills. Grace considers herself a Citizen Scientist. For years, she set of data and evidence and yet when patients experience illness and health in the real world, there are many other variables and factors that need to be factored. According to her, big decisions related to healthcare are shaped mostly by data locked inside clinics and labs, despite the fact that 90% of care happens outside the clinical setting. She believes there are enormous types, format range of patient data that can be gleaned from actual patient experiences when they are not inside the physician clinics. Therefore, to put patients at the forefront of any healthcare development, she established Self Care Catalysts. In 2014, Grace transformed a patient research company into a digital health and data company, building an eco-system that finally connects various healthcare stakeholders to ' Patients arethe Epicenterof our Every Maneuver respected, and engaged, they make better choices for maintaining healthier lifestyle begin generation of real world patient experiences that will drive innovation in clinical research, drug development, commercialization, patient engagement and behavior change. Take on Digital Healthcare Industry According to the organization, technology will continue to play a pivotal role in the healthcare industry. Digital healthcare will redefine patient diagnosis, treatment and post-treatment activities. Traditional hospital will become obsolete and digital therapeutics; digital patient care will become the booming trend in up-coming future. Thisdigital transformation will assist medical professionals in generating greater revenues, cost-reduction, enhanced operational efficiency, and better drug regulation. Everyone, from patient, physician to provider will get benefited with the progression of digital revolution. Future Endeavors Self Care Catalysts has an endeavor to be part of this revolution by catering to varied client needs through its cutting-edge healthcare eco-system. Ultimately, they want to upgrade a business model where physician, patient participation, data ownership and sharing could drive personalized and customized healthcare for all. 'When patients are informed, ' Mobilize Care Actions Care instructions distributed via mobile devices shared by Care Teams Care Teams Family, friends and Professional community care providers Lifestyle Support Access to lifestyle products/services to keep people in their homes Community Care Collaboration (C3) Model Because together, we're better. Our C3 model Community Care Collaboration supports care programs that require high levels of collaboration between interdisciplinary care providers, patients, and family caregivers. Our goal is your goal: to keep patients independent, living comfortably in their homes. Care3.co Check should be drawn in favor of : INSIGHTS SUCCESS MEDIA TECHLLC Yes I would like to subscribe to Insights Care Magazine. Global Subscription 1 Year.......... (12 Issues).... $250.00 6 Months ..... (06 Issues) ..... $130.00 3 Months ... (03 Issues) .... $70.00 1 Month ...... (01 Issue) ..... $25.00 Name : Date : Address : Telephone : Email : City : State : Zip : Country : CORPORATE OFFICE Insights Success Media Tech LLC 555 Metro Place North, Suite 100, Dublin, OH 43017,United States Phone - (614)-602-1754,(302)-319-9947 Email: email@example.com For Subscription : www.insightscare.com SUBSCRIBE TODAY Never M i s s an Issue Company Name Management Brief Biolumo biolumo.eu Olga Grudniak, CEO Marcin Pitek, CSO Wojciech Giowski, CTO & COO Jakub Wysocki, CMO Biolumo is growing MedTech Company that aims to provide the doctors with a device which helps them in making accurate antibiotic prescriptions. healthbank healthbank.coop Reto Schegg CEO healthbank is a health-tech firm that provides cutting-edge solutions for managing clinical data. Intelligent Locations intelligentlocations.io Bogdan Nedelcu Founder & CEO Intelligent Locations is focused on optimizing hospital operations and increasing patient satisfaction by implementing an easy to use Real-Time Location Services (RTLS) platform for the healthcare industry. Kanteron Systems kanteron.com Jorge Cortell CEO & Founder It helps healthcare providers to manage imaging and genomic data effectively, for precision medicine applications at the point of care. Marham marham.pk Ehsan Imam Co-founder Marham is a digital healthcare platform assisting people to find, ask, and consult a doctor. oladoc oladoc.com Abid Zuberi CEO Arif Zuberi CTO oladoc is a healthcare startup provides a leading-edge health-tech platform that solves all challenges that come across a typical patient life-cycle. Patientory patientory.com Chrissa McFarlane Founder & CEO Patientory, Inc. is the leading provider of dApp and blockchain solutions for healthcare sector providing an easy way to securely store and manage health information in real time. Sehat Kahani sehatkahani.com Dr. Sara Saeed Khurram Co-Founder & CEO Dr. Iffat Zafar Aga Co-Founder, Director & CDO Sehat Kahani is an all-female healthcare service provider which aims at providing cost-effective healthcare solutions. Self Care Catalysts selfcarecatalysts.com Grace Castillo-Soyao Founder & CEO Self Care Catalysts is a cloud based analytics company powered by real world evidence to impact health decisions and outcomes of patients, physicians, providers, payer and pharmaceutical industry. Sihatech sihatech.com Ahmed Al-Bader Co-Founder Dr. Mussaad Al-Razouki Co-Founder Sihatech is a digital healthcare company that helps in documenting a patient's medical journey as well as provides financing services to the non-insured medical treatments. clinicians, andhealthcare organizations to access, store and transfer information safely, with blockchaintechnology ' 'W'eempowerconsumers, -Chrissa McFarlane CEO &Founder 18 | July 2018 | PATIENTORY Your Health at Your Fingertips their quality of life and health outcomes, while delivering benefits to all healthcare stakeholders. The Successful Journey of the Company Patientory was incorporated and initiated as part of the inaugural class of the Boomtown Health-Tech Accelerator, in Colorado. This led to a collaborative exchange with the Denver-based Colorado Permanente Medical Group, part of the Kaiser Permanente consortium, based in Oakland, California. Patientory is also part of the Startup Health portfolio, a global organization leading the movement to transform health. In 2017, The Patientory Stiftung was established to be a global not-for-profit, healthcare member- organization that connects healthcare industry adopters of disruptive technologies, right now with a focus on blockchain adoption. It provides neutrality for its PTOY utility currency that provides users access to the platform to store and secure health information. The PTOY coins are utilized to access the PTOYNetTM, a private permissioned blockchain with data storage. This blockchain is similar to that which cryptocurrencies like Bitcoin currently operate upon. Passionate andHumble Leadership of Patientory Chrissa McFarlane is the CEO and Founder of Patientory, Inc. She is a passionate entrepreneur, working towards making a difference in the healthcare sector on a global scale, and has achieved unprecedented success in a highly compressed timeframe. Chrissa is among the youngest female CEOs in the Healthcare IT industry, and is a highly sought after global speaker. She brings more than ten years' experience in the healthcare industry conducting research and managing teams. Her passion for healthcare began in high school, where she conducted microbiology research at the Albert Einstein College of Medicine and won top honors. Later at Cornell University, she worked with organizations such as the US Department of Agriculture. Chrissa is named as one of the top women, "leaving their mark on the medtech field in health IT." As an innovator, she recognized that healthcare provider organizations urgently need secure, scalable, and cost-effective health information management solutions that empower patients and healthcare organizations to use actionable data to make clinical decisions for improved operational efficiency and health outcomes. Thus, Patientory was born. Distinctive Products and Services The Patientory, Inc. dashboard software for healthcare provider and payer organizations, and the Patientory App for consumers, provide easy, secure means to store and better manage health information. The Mobile App empowers consumers to take better control of their health and ealthcare organizations are working for improvements in Hpatient outcomes and operational efficiency, using technology. The 2018Accenture Digital Health Technology Vision Report published in May 2018 states that, "91% of health executives believe blockchain and smart contracts will be critical for their organization over the next three years." This is clearly an exciting time for the healthcare sector as many organizations are adding new technologies, to enhance their operations. This will create better experiences for patients, physicians and healthcare workers. Meanwhile there are rising information security risks, which is why it is vital to begin securing health information in the healthcare blockchain to mitigate health data risk and related financial penalties. Patientory, Inc. is an industry-leading pioneer of blockchain based solutions for healthcare. Incorporated in 2015, Patientory is recognized as an award-winning innovator in healthcare information technology. Many veteran healthcare organizations are calling upon Patientory to discuss its technology solutions and consulting services. It is the first-mover in distributed App (dApp) and blockchain-based software solutions for healthcare that address the complex challenges faced by today's healthcare industry. Its mission is to empower consumers to better manage their own health information, thereby improving Company of the Month | July 2018 | 19 to manage their healthcare information both clinically and financially with greater accuracy and efficiency. Primarily, the app allows easy access and precise sharing of their medical information that is secured within the healthcare blockchain. It provides users better control over their health information, with a more complete picture of their health and goal setting. It allows customers to receive targeted access to health information, healthcare support, educational resources and community. It also enables them to utilize and manage a broader and more efficient array of payment options. The Patientory, Inc., Dashboard is currently testing for large healthcare organizations, with a current EPIC, Cerner, Meditech, or Allscripts installation. This dashboard is a population health management software solution that regulates and safeguards patient data in the blockchain, while providing convenient secure access to actionable health information, and clinical administrative decision support. It enables physician-coordinated care, enhanced by peer-to-peer patient support. Professional Services are for healthcare organizations that leverage Patientory's technology. Typical customers are healthcare organizations that require interoperability or custom use case development. Patientory Professional Services provide customization of the blockchain application, integration, faster deployment, as well as ready access to blockchain technical and expert resources. Patientory's Unique Selling Proposition Patientory solutions empower patients, clinicians and healthcare organizations to readily harness meaningful data to make more effective and efficient treatment, and financial decisions, enabling real improvement opportunities as well as the safe access, store and transfer of information, thus improving care coordination while ensuring data security within a secure HIPAA-compliant PTOYNetTM blockchain. The company offers unique solutions that interconnect with most EHR systems, thereby enabling doctors, care providers and consumers to communicate on a single easy-to-use platform. Also, its solutions will work with almost any healthcare blockchain; bringing together into actionable form many previously inaccessible data sources. These range from EHRs, to patient monitors, wearables, and Apps, connecting this data into a more complete view of a personal health information (PHI). Benefits of the solutions will include the following: Sustainable risk mitigation Patientory takes PHI security to the next level as it uses blockchain technology, ensures end-to-end encryption, and adheres to current regulatory guidelines and compliance requirements. Data risk reduced - HIPAA compliant, reduced risk of PHI data breaches and related penalties Patient risk reduced - greater consumer engagement, control, and responsibility with their PHI Financial risk reduced reduc readmissions, broader reimbursement options Operational performance improvement and efficiency More efficient access to health datfor physicians saves time Better controlled access to curent PHI, from a wider range of current data sources More proficient access to sources of payment, and rules of payment for claim resolution Financial performance improvement Enables efficiency for diverse payment methods (including cryptocurrencies and soon electronic claim reimbursement) Saves costs by reducing the need for duplicative tests/radiological scans and related measures Recent Accolades Patientory, Inc. has been recognized with accolades including the following: Ranked Top 5 digital health solutionin the world for empowering patients, alongside multi-million- dollar revenue companies Voted Top 10 Amplify Women in Technology Startup Company out of 139 startups 2018 Globe Award Winner in International Trade by U.S. State of Georgia Top 11 Company Disrupting Healthcare in 2017 2017 Company of the Year by the Metro Atlanta Chamber Future Perspective Healthcare is embracing a wave of technology and cultural changes. Patientory's vision is to provide solutions that will enable doctors, care providers and consumers to communicate on a single easy-to-use platform, one that interconnects with most EHR systems, while also enabling a wider array of payment types. Patientory, is continuing to lead advancements in artificial intelligence, blockchain, and is working with the industry's uptake of the Internet of Things (IoT) to better serve healthcare consumers, providers, payers and BioTech while creating a more accessible, efficient, effective continuum of care throughout a patient's life, and wherever they may travel. Company of the Month | July 2018 | 20 n world of medicines, the most frequently prescribed one is antibiotics. Yet, every solution Ithat might help the general practitioners to prescribe the right antibiotic is beyond their reach. Asa result, they have to guess and statistically there are only 50% chances that they guess right. Biolumo is a company which will help the practitioners in prescribing proper antibiotics. Biolumo is an innovative and growing MedTech company that aims to provide the doctors with a device which helps them in making accurate antibiotic recommendations. The device is fast enough to test every patient as well as affordable for both, doctors and the patients. In a long perspective, it will be developed for the governments or the healthcare providers. They aim to design, test, and mass-produce an inexpensive and rapid point-to-care tool. The Exemplary Leader for Biolumo Olga Grudniak, the CEO, is an adept leader for a MedTech company due to her interest and expertise in economy as well as biotechnology. She has inherited the "business genes" from her father, who established many successful enterprises, and "science genes" from her mother. This has helped her to find the balance between the good of the company and the benefits that their science can bring to the healthcare. The entire team of Biolumo has two very important features- they are persistent and systematic. These qualities have inculcated in them the habit of not giving up in difficult situations and seeking ideas to solve any problem that comes as an obstacle to them. Biolumo: An Ingenious Solution for Precise AntibioticSelection We aim tohelp you inprecise antibiotic selection ' ' Olga Grudniak CEO 22 | July 2018 | Pacing through their Story The idea of Biolumo came to them in 2016, from a phone call. A friend, whose son had a bacterial infection, had called them to ask for a solution to quickly determine the right antibiotic for his son. Their research in-charge, Marcin Pitek, now the CSO of the company, did not find any existing answers to that question, but knew how to do it. From that moment on, with the help of many mentors and experts, the idea of Biolumo turned into a complete concept. Featuring in a prestigious conference, Infoshare- 2017 was a breakthrough for them. Thereafter, they were invited to the Start-up boot camp in Berlin and started appearing in all the major conferences in Poland, like The Chivas Venture and Impact'18. Recently, they were honoured as one of the biggest innovators in Polish MedTech by receiving Healthcare Leader's Competition award. Developing a Radical Product and Future Aims Biolumo is developing a device for quick antibiotic resistance detection for healthcare as its core product. This device is being designed from scratch to be implemented in a mass, which means the hardware will not be that sophisticated and hence, will be made in large quantities at a low price. Along with being affordable for the GPs as wel as the patients, the device will be fast and easy to use. In the next six months, they will enter into clinical validation by testing the product on patients' samples and comparing it with antibiogram, the golden standard. Biolumo's target is to introduce the product to the market in two years. Next in the pipeline, they have a tool for antibiotic resistance and bacterial infection detection for vets and livestock breeders, for which they have got the EU grant. This is estimated to enter the market in four years. Biolumo's Take on Effects of Technological Advancements on Healthcare Without easy access to new technologies, like the clouds and servers, fast exchange of data, 3D printing, AI, and IoT, digital healthcare solutions wouldn't have been possible. Jakub Wysocki, the CMO, talks about how the most important change the technology can bring in healthcare is to treat every patient individually. Different people with the same infection react differently to the same antibiotic and therefore, moving a step closer to the personalized treatment will be a breakthrough in the healthcare sector. Strategy against the Challenges Wojciech Giowski, the CTO & COO, talks about how they keep the check of their competition, but the main strategy is to continuously improve their technology. They are well-informed about the changes in laws, procedures, and so on, which helps them to stay up-to-date with the emerging trends. Improving their solutions according to the market needs helps Biolumo to stay ahead in the competition. To better adapt to the changes, Biolumo is thinking about implementing the TRIZ methodology, which can be used to improve the competitiveness of their technology. A Word on the Future of Digital Healthcare Solutions "With all the enhancements the technology has brought to the world, medicine- the most important for our lives, is still underdeveloped. But slowly the change is coming, with quick diagnostic tools for viruses, cancer, cardiovascular diseases, genetic diseases, and of course bacterial infection, and that is the future," says Olga. She further talks about how with decrease in the number of doctors and healthcare professionals, the diagnosis in the future will be outsourced to the patients themselves, for which all the new MedTech solutions should be easy to use, affordable and quick. Biolumo is focused on delivering one such solution with the development of their device. | July 2018 | 23 T and mobile revolution has changed the landscape of many businesses and healthcare too is not an report, or just a normal pathological lab report every data can be stored digitally or even on cloud with just a few clicks of a device. All these reports and patient history generate mammoth amount of data every year which often get stored in a closed eco-system and remain dormant. Stakeholders thus cannot process and derive meaningful insights from this valuable data as they don't have access to the comprehensive record of any individual. To alter this scenario and to revolutionize how personal health data is exchanged, stored and monetized, healthbank got incepted. The firm empowers all the healthcare stakeholders by providing an open eco- system that enables users to securely store and exchange data with a range of healthcare, pharmaceutical and wellness & lifestyle service providers at the user's request. healthbank provides an independent and neutral solution, that only the user has access to yet provides access to a vast amount of health services in the open eco-system. Incepted in 2013, this Switzerland based health-tech firm is gaining popularity with its leading-edge healthcare solutions. Today, healthbank consists of two symbiotic organizations: healthbank cooperative is the core solution which stores patient data on a fully secure digital platform - governed by people (members). What makes it unique is healthbank cooperative is owned by the people, controlled by the people, and the profit also goes back to the people. healthbank: Transforming the Way Health Data get Exchanged, Stored andMonetized Iexception. Whether it is an X-ray report, a MRI We are giving back the control of personal health data into the hands of its rightful owners i.e. thepeople ' ' Reto Schegg CEO 24 | July 2018 | healthbank innovation AG as the platform manager responsible for the development of services, apps, integration of partners, and data processing on behalf of the user. About the Company This Switzerland based firm was founded when an international team of 28 academics, entrepreneurs and experts of the healthcare industry came together with the intent to give back the control of personal health data into the hands of its rightful owners i.e. the people. The company's vision is to empower people across the globe to exchange their health data, on their uniquely neutral and independent platform. Uniqueness of healthbank is its policy of 'one-person-one- vote' which develops a greater sense of trust among all its stakeholders and encourages greater participation. This policy is one of the prime factors behind healthbank's stupendous success. When it comes to health data, they put people at the center of every maneuver. Their ultimate aim is to bring together market players and help them to participate in an open eco-system connected to the healthcare market. They believe that open ecosystems are more efficient than closed ones. Therefore, health service providers benefit from joining healthbank and will be able to integrate their service with customer data and other service providers to more comprehensive solutions. Benefits of its Eco-system Technological Security: Through a full-fledged end-to-end encryption as well as a high-security software architecture concept, healthbank provides the right ecosystem partnership to safely manage health data for ecosystem partners that rather want to focus on their first-class services and products than on data back ends. Full Independence: healthbank provides a truly open and neutral ecosystem that comes with long-term stability as well as competition on the platform itself. Real World Patient Information: As soon as the users give their consent, the app service provider can integrate dozens of other data sources to enhance their own services through big data, artificial intelligence or machine learning algorithms. Full GDPR compliance: Due to its detailed, informed and dynamic consent management, which puts the user in the middle of the decision process to connect, store and share personal data; healthbank helps achieving full GDPR compliance for their application partners from the ecosystem. Future Endeavors The company will soon follow a much more robust architectural approach and will raise its data security to the utmost level through end-to-end encryption The range of functions for users will also get expanded. The health platforms get refurbished to integrate further partners and applications from the health sector quickly, efficiently and more securely. With the new software architecture and the implemented security mechanisms, healthbank is ready to connect further partners and applications with a healthbank account. Their two award-winning apps "CatchMyPain" and "PainCompanion" will soon be integrated into the healthbank. Users suffering from severe or chronic pain can benefit from the long-term pain documentation in the future and continue to share their experiences and thoughts. healthbank works closely with the Swiss app developer "Rehaptix". Rehaptix monitors the rehabilitation of patients with motor disabilities due to a neurological injury such as stroke, multiple sclerosis or Parkinson's disease. All data generated in the app is securely stored in the healthbank and can also be passed on to other people. healthbank plans to integrate fitness trackers into the healthbank in the near future. With this service users can connect their fitness tracker with the healthbank. And ifa user changes the tracker, this will no longer be a problem in the future - the data and the connection to the healthbank will remain intact. The trailblazer behind its Success Reto Schegg, Chief Executive Officer, has proficiency in eHealth projects. He was involved in many of the big eHealth initiatives in Europe in recent years. Holding master's degrees in Electrical Engineering, Business Administration, and Business Law, he has been responsible for international health tech business lines and sales teams. Reto drives the idea of encouraging citizens to make better decisions about their own health in order to receive the best possible care. | July 2018 | 25 26 | July 2018 | A Non-InvasiveApproach Intended forPersonalized Care of CancerPatients Liq u i d Bio psy: ancer has been the talk of the town for many years now. The main obstacle that Cancer Cpatients face is the late detection of the disease that causes sixteen percent of the deaths around the world. A biopsy is a method which is generally used to diagnose cancer. It involves sampling of the tissue or cells from any part of the body that is affected and checks it for cancer, which is a highly invasive and costly technique. Traditionally, cancer diagnosis has been carried out by pathology and medical imaging. This included tissue biopsies, serological indicators such as CEA and PSA test, molecular pathology test, Ultrasonic testing, X-ray imaging, CT-scan, MRI, PET-CT, and endoscopy. The real-time diagnosis is not possible with these tests, since in imaging there is usually a lag in the tumor progression, while in the serological indicators there is a lack of effective bio-makers for early diagnosis. Inventive Diagnostic Tool | July2018 | 27 Although tissue biopsy is considered a potent technique, the patient faces severe clinical complications during sampling. Also in case of terminal cancer patients, it is very difficult to obtain tissue samples. Due to this, it has become the need of the hour to look for new biomarkers that are highly sensitive and specific to tumor diagnosis. This will help in monitoring tumor progression. Recently, researchers have proposed a new technique which involves only a blood test, known as Liquid Biopsy. It is gaining ground all over the world and has been referred to as the potential game changer. Although, professionals believe it requires a couple of years of development to become a vital screening tool worldwide. Using this technology, doctors will be able to screen cancer using only a small sample of the patients' blood. Liquid biopsy would be a huge leap in deterrent cancer treatment. It will help doctors to provide a personalized and targeted treatment (aiming only the cancer cells and killing them). Essentially, liquid biopsy is an analytically sensitive blood test which can detect a single tumor cell loitering among a billion normal cells. This process would be carried out in real time and will transform cancer diagnosis and control. Mechanism of Action This test examines cancer related proteins and DNA that is available in the blood of the patient before cancer spreads. It also helps the doctor to narrow down the form of cancer which is present. The cells of a tumor are continuously shed, allowing the tumor's DNA to be released into the bloodstream; no matter where the tumor is. This tumor DNA that is found in the bloodstream is termed as ctDNA (circulating tumor DNA). Liquid biopsies target the ctDNA, which makes it the most non-invasive technique. This ctDNA has been used by scientists to monitor and check for genetic changes that might impact treatment. The protein markers are used to help determine the site of the tumor, to provide a specific and correct diagnosis. Why Choose Liquid Biopsy Over Traditional Diagnosis? Liquid biopsy being non-invasive makes it feasible for the doctors to take frequent samples, without causing discomfort to the patient. It has very few side effects, it is easy to maneuver, has a high testing speed, which helps decrease the bias in diagnosis and helps doctors understand the progression of cancer. This permits it to be done frequently to observe the treatment's effect. Combining a cell-free DNA marker with a known protein marker (for several common types of cancer) has allowed scientists to throw some light on where cancer may be found. Cancer's genetics which plays a major role in the development of the disease can be studied using liquid Inventive Diagnostic Tool biopsy. This will provide new and valuable information regarding the complex mechanism involved in drug resistance and progression. Liquid biopsy has a pleasing future in early diagnosis, cancer drug design, determining the mechanism of drug resistance, assessment of tumor's grade and stage, arbitrating prognosis and regulating the treatment plan. Complications That Need to Be Overcome There are a few characteristics of the test that have yet to be addressed further, like the primary or initial stages of tumor might be small and easily missed. Researchers are trying to solve the problem of small quantities of ctDNA. Even with a medium sized tumor, the ctDNA is very small, making it difficult to detect and diagnose. Also, ctDNA is not the only DNA that is moving around in the bloodstream; pregnant women have placental DNA from the baby's placenta in their blood which might cause misreading. Patients who have suffered from a heart attack also have DNA fragments in their blood. Accurate identification of the ctDNA from the other DNA is a problem that needs to be addressed to evade false alarms; telling somebody they have cancer when they don't could be disastrous. Although liquid biopsies provide valuable insights into the progression of cancer, it does not currently provide any insights into the origin of cancer. Studies are still being conducted to refine the technology to throw some light on the nature of cancer (its mutations), its place of origin and so on. The cells that have metastasized may gain bonus genetic characteristics over time and grow individually away from the primary tumor. Direct analysis of the metastasized cells is required so that the patient is provided with specific therapy and side effects can be avoided. This method would provide the diagnosis of cancer before the symptoms start showing. Although this is anadvantage, pre-symptom testing could cause a scare, since cancer cells are produced by the body continuously and they get killed internally. The tests are expensive. Not all cancers are aggressive and lethal, some are slowly progressing, and are not fatal, thus do not require any treatment. The method should be further developed to differentiate which tumor can be left alone and which require treatment. As scientific information advances, researchers are unveiling various potential aspects of liquid biopsies; to detect mutations, determining the position of the tumor. This suggests that the technology promises a powerful diagnostic technology that could be game-changing. More substantiation, development and clinical trials are required to completely understand the value of liquid biopsies in a medical setting. 28 | July 2018 | enetic testing, especially molecular genetic diagnostics, has evolved rapidly since the advent Gof the twenty-first century, thereby prompting a corresponding evolution in patient management and the healthcare industry. Recent advances in molecular biology research have opened a portal to plenty of phenomenon that were previously heard of only in science fiction, such as gene editing, personalized medicine, and even designer babies. A literal interpretation of the term 'genetic testing' would refer to the analysis of changes (known as mutations) in the hereditary material or DNA (deoxyribonucleic acid) of an individual or group of individuals to confirm or predict health-related outcome
Such healthcare providers always foster a healthy team environment at their workplace and engage in behaviors that benefit the team and display empathic behaviors when interacting with patients and their family members. To highlight such great healthcare providers, we have come up with an issue of “The 10 Most Innovative Digital Healthcare Solution Providers 2018”.
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