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Gold Nanoparticles labeled Peptides
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* Please be kindly noted that our services can only be used for research to organizations or companies and not intended for any clinical or individuals.
The gold nanoparticles provided by BOC Sciences have high efficiency and sensitivity in applications in the fields of chemistry, biological analysis, biomedicine,
optics and nanotechnology. With a comprehensive advanced platform, BOC Sciences provides gold nanoparticles labeled peptides services to customers
worldwide to promote your research.
Gold nanoparticles have unique optical properties, such as surface plasmon resonance, resonance light scattering, easy surface modification, and good
biocompatibility. The combination of peptides coupled to the surface of gold nanoparticles has many potential applications in chemistry, biology, and medicine.
Polypeptide was coupled to the surface of gold nanoparticles and activated by 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride (EDC) and N-
hydroxysuccinimide (NHS) reaction is the most commonly used coupling method. Generally, a two-step activation reaction is required: first, alkanoic acid
containing mercapto groups is assembled on the surface of gold nanoparticles through gold-sulfur bonds to form a monomolecular layer. Then, the carboxyl
group is activated by EDC-NHS, dehydrated and condensed with the amino group of polypeptide or protein, and finally forms amide bond.
Peptide and gold nanoparticle conjugates have been used in the study of immune recognition, transcription factors, mimic enzymes and protein inhibitors in
biological simulation systems. A novel layer-by-layer coupling assembly system based on gold nanoparticles was designed. The assembly system combines
fluorescence imaging, efficient cell entry, mitochondrial targeted transport and other functions,