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ABSTRACT
OBJECTIVE: To assess the effects of transurethral resection of prostate (TURP) on
urinary flow rate / uroflowmetry in patients with benign prostatic hyperplasia preoperatively
and following transurethral resection of prostate (TURP) for three months post opera
operatively.
MATERIALS AND METHODS: This prospective study was conducted at department of
urological surgery and transplantation at Jinnah post graduate medical centre (JPMC)
Karachi between March 1999 to March 2002. Fifty consecutive patients age range 50
years to 80 years, on clinically diagnosed of benign prostatic hyperplasia (BPH) were
include in the study, Preoperatively uroflowmetry is carried out followed by uroflowmetry
post transurethral resection of prostate (TURP), after first month, second month and
third month.
RESULTS: Mean age 63.62±6.75 years.
Uroflowmetry parameter among fifty patients before operation (TURP) are found, mean
voiding time 32.37 ± 19.19 seconds, mean flow time 28.57 ± 15.79 seconds, mean time
to maximum flow 9.64 ± 6.65 seconds, mean maximum follow rate 7.60 ±2.41 ml/sec,
mean average flow rate 4.41 ±1.28ml/sec and mean voided volume 165.54 ml. Postoperative
(TURP) uroflowmetry was carried out after first month, second month and third month’s.
The average of first three months of postoperative follow up uroflowmetry parameter
obtained are, voiding time 27.64±11.67 (P=0.14) seconds, flow time 25.72±11.00 (P=0.29)
seconds, time to maximum flow 6.59 ± 0.79 (P=0.05) second maximum flow rate 27.24
±5.11 (P=0.001) ml second, average flow rate 13.48 ± 2.08 (P= 0.001) ml second,
voided volume 240.32 ± 49.91 (P=0.01) ml.
The change in average from first month to third month of operation, uroflowmetry
parameters found statistically significant in time to maximum flow, maximum flow rate,
average flow rate and voided volume. While voiding time, and flow time are determine
statistically non-significant, when tested by F-statistics.
CONCLUSION: We conclude that the effects of post transurethral resection of prostate,
all the