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Home > Products > Organocatalysts > Asymmetric Organocatalysts > Chiral Diols
Among the many chiral compounds, chiral diols are compounds containing two hydroxyl groups in a chiral
molecule. It can not only participate in many life activities but also can be used as a very important chiral
cleavage and chiral intermediate. Chiral diols are also a wide range of chiral ligands that are widely used.
Moreover, they are also raw materials for the preparation of chiral compounds such as chiral diamines and
diphosphines. It plays an important role in the fields of medicine, chemical industry, food, agriculture, and
Chiral diols are widely used as chiral ligands and chiral catalysts in asymmetric synthesis. The chiral ligand can
provide the chiral environment required for the reaction, and the chiral catalyst is a metal organic compound
formed by the complex of a chiral ligand with a central metal. Therefore, it can be widely used in asymmetric
catalytic reactions. For example, asymmetric hydrogenation, asymmetric oxidation, asymmetric aldol
condensation, asymmetric Reformatsky reaction, and the like.
The preparation methods of common chiral diols include enantioselective reduction, chiral resolution, olefin
epoxidation ring opening, olefin asymmetric di-lightening, aldehyde ketone reduction coupling link, and
chemical conversion of chiral compounds.
Enantioselective reduction reaction□The corresponding diol can be obtained by reduction of the diketone
using a borane reagent. If some chiral catalyst is added during this process, an enantioselective reduction
can be carried o