University of Texas
M.D. Anderson Cancer Center
Department of Epidemiology
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Brain Tumor Epidemiology
Consortium (BTEC)
Melissa Bondy, Ph.D.
University of Texas
M.D. Anderson Cancer Center
Department of Epidemiology
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Overview of Brain Tumors
• 17,000 new cases and 13,100 deaths expected
in 2004
•Most frequent solid tumor in children
•More frequent in males than females
• Lower rates in non-whites
• Rates are increasing especially in adults over
age 65
University of Texas
M.D. Anderson Cancer Center
Department of Epidemiology
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Brain Tumor Incidence
.
Incidence of malignant primary CNS tumors by age
and histology,
SEER, 1986-1997
0
5
10
15
20
25
00-0410-1420-2430-3440-4450-5460-6470-7480-84Age (in years) at diagnosis
Average annual rate per 100,000 person-yearsAll CNS
High grade glioma
Low grade glioma
Oligodendroglioma
PNET
Ependymoma
Meningioma
Germ Cell
Other
University of Texas
M.D. Anderson Cancer Center
Department of Epidemiology
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Chronology of BTEC
• February 2003 - 1st meeting organized by NCI
(Peter Inskip)
• November 2003 - 2nd meeting held in
conjunction with Society for Neurooncology
–Sought funding for future meetings from
brain tumor foundations (National Brain
Tumor Foundation, Pediatric Brain Tumor
Foundation, American Brain Tumor
Foundation)
–Arrangements and coordination by Central
Brain Tumor Registry of the United States
(CBTRUS – Carol Kruchko)
–Research groups and leadership established
University of Texas
M.D. Anderson Cancer Center
Department of Epidemiology
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Goals
• Develop a mission statement
• Organize planning committee
• Develop consortium structure
• Identify research group chairs
• Identify U.S. and international investigators
conducting epidemiologic research in brain
tumors for future involvement
University of Texas
M.D. Anderson Cancer Center
Department of Epidemiology
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