ORASURE TECHNOLOGIES, INC.
LOAN AND SECURITY AGREEMENT
September 10, 2002
This LOAN AND SECURITY AGREEMENT is entered into as of September 10, 2002, by and between
COMERICA BANK--CALIFORNIA ("Bank") and ORASURE TECHNOLOGIES, INC., a Delaware
Borrower wishes to obtain credit from time to time from Bank, and Bank desires to extend credit to Borrower.
This Agreement sets forth the terms on which Bank will advance credit to Borrower, and Borrower will repay the
amounts owing to Bank.
The parties agree as follows:
1. DEFINITIONS AND CONSTRUCTION.
1.1 Definitions. As used in this Agreement, all capitalized terms shall have the definitions set forth on Exhibit A.
Any term used in the Code and not defined herein shall have the meaning given to the term in the Code.
1.2 Accounting Terms. Any accounting term not specifically defined on Exhibit A shall be construed in
accordance with GAAP and all calculations shall be made in accordance with GAAP. The term "financial
statements" shall include the notes and schedules accompanying such financial statements to the extent such
statements are for an annual or quarterly period.
2. LOAN AND TERMS OF PAYMENT.
2.1 Credit Extensions.
(a) Loans; Promise to Pay. Bank agrees to advance Borrower Credit Extensions, in lawful money of the United
States of America, pursuant to the terms hereof. Borrower promises to pay to Bank, in lawful money of the
United States of America, the aggregate unpaid principal amount of all Credit Extensions made by Bank to
Borrower, together with interest accrued on the unpaid principal amount of such Credit Extensions, at rates
determined in accordance with the terms hereof.
(b) Revolving Advances.
(i) Amount. Subject to and upon the terms and conditions of this Agreement, Borrower may from time to time
request, and Bank will provide, Revolving Advances in an aggregate outstanding amount not to exceed the lesser
of (A) the Committed Revolving Line Amount or