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Active pharmaceutical ingredient (API) synthesis is usually a complicated and multi-step process involving numerous...
Active Pharmaceutical Ingredient (API) is defined by U.S. Food & Drug Administration as: any substance or mixture
of substances intended to be used as the active ingredient in the manufacture of a drug (medicinal) product. Such
substances are intended to furnish pharmacological activity or other direct effect in the diagnosis, cure,
mitigation, treatment, or prevention of disease or to affect the structure or function of the body. API may exist in
the form of liquids, powders, crystals and extracts that obtained by chemical synthesis, plant extraction, or
biotechnology and is not taken by patients directly. Only when API is processed into a pharmaceutical
preparation, can the product be used for clinical use. The synthesis of APIs is usually a complicated and multi-step
process involving numerous chemical transformations and operations on a range of raw materials with different
physical and chemical properties. Specialized expertise is needed to achieve the synthesis of these molecules. BOC
Sciences with seasoned chemists would provide a comprehensive supply of guaranteed API synthesis service.
Methods of API Synthesis:
There are certain inorganic molecules can be used as active pharmaceuticals ingredients. Taking the
aluminium hydroxide (the synthesis route is displayed as below) as an example, which is a typical inorganic
API that reacts with excess gastric acid to reduce the acidity in the stomach, it can significantly relieve the
symptoms including ulcer, indigestion and heartburn.
2NaOH + CO = Na CO + H O
NaAl(OH) = Al(OH) ↓+NaOH
Building Block Synthesis
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