National Nanotechnology Initiative (NNI)
Nanoscale Science Engineering and Technology subcommittee (NSET)
Nanoscale Environmental and Health Implications (NEHI)
Environmental, Health, and Safety Research Needs
for Engineered Nanoscale Materials
(www.nano.gov)
Dr. James Murday
Past, Executive Secretary of NSET
Now, Univ of Southern California
Engineered nanoscale materials – purposefully manufactured or synthesized
EHS research needs document is specifically NOT associated with:
naturally occurring nanomaterials
incidental byproducts of manufacturing, combustion, …
However, the substantial body of knowledge about risks related to exposures to
these categories will inform risk assessment and management for engineered
nanoscale materials
Instrumentation, Metrology and Analytical Methods
Research and Information Needs
• Methods for detecting nanomaterials in
biological matrices / environment / workplace
• Methods for standardizing particle size and size distribution
• Standardized tools for assessing nanomaterial shape,
structure, and surface area
• An inventory of engineered nanomaterials and their uses
Nanomaterials and Human Health
Research and Information Needs
• Methods to quantify / characterize exposure to nanomaterials in biological matrices
• Understanding absorption / transport of nanomaterials throughout the body
• Understanding the properties of nanoscale materials eliciting biological response
•
In vitro and in vivo assays/models to predict in vivo human responses to exposure
Nanomaterials and the Environment
Research and Information Needs
• Evaluation of testing schemes for ecological effects
• Factors affecting the transport of nanomaterials in the environment
• Understanding transformation of nanomaterials under different
environmental conditions
Health and Environmental Surveillance
Research and Information Needs
• Workplace processes and factors that affect exposure to
nanomaterials
• Quantification of nanomaterial exposure from industrial processes,
consumer products and other product