THIRD AMENDMENT TO LEASE
AMENDMENT TO LEASE dated March 21,1996 by and between EASTPARK AT 8A, having an office at
1000 Eastpark Blvd., Cranbury, New Jersey 08512, (hereinafter called the "Landlord"); and
PHARMACOPEIA, INC., having an office at 101 College Road East, Princeton Forrestal Center, Princeton,
NJ 08540 (hereinafter called the "Tenant").
WHEREAS, the parties entered into a Lease Agreement dated September 28, 1995, a First Amendment to
Lease dated January 22, 1996 and a Second Amendment to Lease dated January 22, 1996 ("Lease"), in
connection with the leasing of office and warehouse space at 3000 Eastpark Blvd., Cranbury, NJ 08512; and
WHEREAS, the parties wish to amend the Lease;
NOW, THEREFORE, the parties hereto covenant and agree as follows:
1. The Leased Premises shall be expanded by 15,472 square feet so that Tenant shall occupy all of Expansion
Space 1 as described in Paragraph 1.2 of the First Amendment to Lease. The total square footage leased by
Tenant shall, therefore, be revised to 33,534 square feet consisting of all of the original space plus all of
Expansion Space 1.
2. As a result of exercising Option 1, Tenant shall have the right to exercise the 2 further options set forth in
Paragraph 1.3 of the First Amendment to Lease.
3. The rent in Paragraph 4 shall be revised to be $702,607.82 in equal monthly installments in the sum of
$58,550.65, to commence upon Substantial Completion. This sum is calculated as follows:
a. For the first 18,062 square feet, rent of $450,259.50, calculated at $25.50 per square foot for 17,079 square
feet and $15.00 per square foot for 983 square feet;
b. For the remaining 15,472 square feet, rent of $252,348.32, based on an August 1, 1996 occupancy at a rent
of $16.31 per square foot. The $16.31 figure is calculated based on the figure of $18.00 per square foot set forth
in paragraph 4.2 of the original Lease, less a credit to Tenant of $2.25 per square foot for extending the lease
from 5 to 1O years; plus $.1