Exhibit 10.57
BIOGEN IDEC INC.
2006 NON-EMPLOYEE DIRECTORS EQUITY PLAN
First Amendment
Pursuant to Section 17 of the Biogen Idec Inc. 2006 Non-Employee Directors Equity Plan (the "Plan"), the
following clarifying amendments are hereby made to
Section 7(d) of the Plan, effective as of the Plan's Effective Date:
1. Section 7(d)(i) is amended to read in its entirety as follows: "In the event that the Participant's Board service
shall terminate on account of the Retirement of the Participant, each Option granted to such Participant that is
outstanding as of the date of such termination shall become fully exercisable and shall remain exercisable by the
Participant (or, in the event of the Participant's death while such Option is still outstanding, by the Participant's
legal representatives, heirs or legatees) for the three year period following such termination (or for such other
period as may be provided by the Committee), but in no event following the expiration of its term."
2. Section 7(d)(iii) is amended to read in its entirety as follows: "In the event that the Participant's Board service
shall terminate on account of the Disability of the Participant, each Option granted to such Participant that is
outstanding as of the date of such termination shall become fully exercisable and shall remain exercisable by the
Participant (or such Participant's legal representatives or, in the event of the Participant's death while such Option
is still outstanding, such Participant's legal representatives, heirs or legatees) for the one year period following
such termination (or for such other period as may be provided by the Committee), but in no event following the
expiration of its term."
3. Section 7(d)(vi) is amended to read in its entirety as follows: "In the event of the Participant's death within six
months following the Participant's termination of Board service for any reason other than (A) Retirement, (B)
death, (C) Disability or (D) For Cause, each Option granted to such Participant tha