European Journal of Internal Medicine 17 (2006) 514–516
Inf lammatory pseudotumor: A diagnostic dilemma
Débora M.S. Andrade a, Sandro J. Martins b, Otávio Paz a, Juliana B. Cardozo a,
Albino E. Novaes a, Mittermayer B. Santiago c,⁎
a Hospital Universitário Professor Edgar Santos, Brazil
b Hospital Santa Izabel (HSI), Brazil
c Escola Bahiana de Medicina e Saúde Pública, Brazil
Received 11 January 2006; received in revised form 14 March 2006; accepted 27 March 2006
Inflammatory pseudotumor (IP) is a disorder that constitutes a differential diagnosis of a series of clinical conditions due to a large
spectrum of manifestations in presentation since it can involve any organ of the human body. Its basic characteristic is the appearance of
inflammatory masses whose symptoms depend on their location. We describe two cases of IP that clearly illustrate this diversity of
presentation and we review the diagnostic and therapeutic strategies for such a condition.
© 2006 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
Keywords: Inflammatory pseudotumor; Lymphadenopathy
Inflammatory pseudotumor (IP) is a clinical condition
characterized by the appearance of inflammatory masses that
occur mainly in the lungs, liver and retro-orbital space but
that can also occur anywhere else. It represents a diagnostic
challenge, given the multiplicity and non-specificity of its
clinical, radiological and laboratory manifestations . The
objective of the present work is to describe two cases of IP
that demanded ample diagnostic investigation, involving
various specialists, before its definition. A literature review
was also performed on this subject.
2. Case reports
2.1. Case 1
A 42-year-old black female patient had a history of
lymphadenopathy in the cervical and inguinal region in
⁎ Corresponding author. Serviço de Reumatologia do Hospital Santa Izabel
Praça Almeida Couto, 500, Nazaré, Salvador, Bahia CEP 40.000-000, Brazil.