Brand – TYKERB
Generic – LAPATINIB / DITOSYLATE
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TYKERB / LAPATINIB / DITOSYLATE tablets
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What is LAPATINIB?
Lapatinib is used to treat advanced hormone-related breast cancer that has progressed or spread after
treatment with other cancer medicines.
Lapatinib is used for this condition only if your tumor tests positive for a protein called human epidermal
growth factor receptor 2 (HER2). HER2 protein can speed the growth of cancer cells.
In postmenopausal women, lapatinib is given in combination with a hormonal medicine called letrozole
(Femara). In others, lapatinib is given together with a cancer medicine called capecitabine (Xeloda).
Lapatinib may also be used for purposes not listed in this medication guide.
Do not use lapatinib if you are pregnant. It could harm the unborn baby.
Lapatinib can cause severe or fatal liver problems. Call your doctor at once if you have: upper stomach pain,
itching, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).
Source : https://www.drugs.com/mtm/lapatinib.html
How should I take LAPATINIB?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the
medicine exactly as directed.
When used with letrozole, the usual dose of lapatinib is 6 tablets taken once daily every day. Letrozole is also
taken every day.
When used with capecitabine, the usual dose of lapatinib 5 tablets taken once daily for 21 days in a row.
Capecitabine is also taken twice daily for only the first 14 days. This 21-day cycle is then repeated.
Follow your doctor's dosing instructions very carefully.
Take lapatinib on an empty stomach, at least 1 hour before or 1 hour after a meal.
You may swallow each lapatinib tablet one at a time, but take the entire dose (all 5 or 6 tablets) at the same
time each day.
Capecitabine must be taken with food or within 30 minutes of eating.
Source : https://www.drugs