T HIS S UBLEASE (“Sublease”), dated December 19, 2001 for reference purposes only, is entered into by and between C
OOLEY G ODWARD LLP , a California limited liability partnership (“Sublandlord”), and H OLLIS -E DEN P HARMACEUTICALS , I
NC ., a Delaware corporation (“Subtenant”).
A. Sublandlord is the tenant under that certain Office Building Lease dated June 22, 2000 (the “Original Lease” ), by
and between Frazee East Property Partners, L.P., a California limited partnership ( “Master Landlord” ), and Sublandlord, as
amended by a First Amendment dated December 18, 2000 (the “First Amendment” ) and a Second Amendment dated June 26,
2001 (the “Second Amendment” ). The Original Lease, the First Amendment and Second Amendment are collectively referred to
as the “Master Lease.” A copy of the Master Lease is attached hereto as Exhibit A . Pursuant to the Master Lease, Sublandlord
is currently leasing approximately 137,624 Rentable Square Feet of office space on the third (3rd) and fourth (4th), floors of the
building located at 4435 Eastgate Mall ( “Building 3” ) and all four (4) floors in the building located at 4401 Eastgate Mall
( “Building 4” ), San Diego, California (collectively, the “Master Premises” ). All initially capitalized terms not otherwise
defined herein shall have the same meanings as set forth in the Master Lease.
B. Subtenant desires to sublease the entire Rentable Square Footage on the fourth (4 th ) floor of Building 3 (the
“Sublease Premises” ) from Sublandlord, and Sublandlord desires to sublease the Sublease Premises to Subtenant, upon the
terms, covenants and conditions herein set forth.
N OW , T HEREFORE , in consideration of the mutual covenants and conditions contained herein, Sublandlord and
Subtenant covenant and agree as follows:
1. Sublease Premises . On and subject to the terms and conditions below, Sublandlord hereby leases to Subtenant,
and Subtenant hereby leases fro