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Liposome Formulation Development
Formula Feasibility Studies
For a long time, BOC Sciences’s focus has been the drug development. Our extensive experience has made us an expert in the design and manufacture
of liposome drugs.
Liposomes are nano-drug delivery systems that have been successfully transformed into real-time clinical applications. These bilayer phospholipid
vesicles have witnessed many technological advances in recent years. The therapeutic agents encapsulated inside liposomes change their
biodistribution characteristics, thereby further improving the therapeutic index of various drugs. Extensive research is being performed in these areas
using liposomes as drug delivery systems, including the delivery of anticancer, antifungal, anti-inflammatory drugs, and therapeutic genes.
Benefits of Drug Load in Liposomes
Protection - Liposomes protect drugs from degradation. In vivo, liposomes can extend the biological half-life of the life.
Improved solubility of lipophilic and amphiphilic drugs.
Liposomes can localize, target and specifically interact with the affected tissue.
Liposomes constitute a reservoir of drugs, which can continuously release the drugs and reduce the side effects caused by the frequency of use.
Minimal toxicity - Liposomal preparations are used in cancer treatment to reduce the toxic side effects of drugs.
Figure 1: Schematics showing the advantages of formulating drugs in liposomes (Upendra Bulbake. 2017).
BOC Sciences can help to solve issues and requirements related to your current and future research of liposome pharmaceutical formulations through
our liposome research and manufacturing services. Our liposome platform has been able to develop liposome formulations with varying sizes (20nm to
200nm), payloads (e.g. nucleic acids, hydrophobic drugs) and excipient characteristics (e.g. charge and pH adjus