A CASE OF PSORIASIS ON VITILIGINOUS AREAS
~ E R ~ N D E
B ~ R
P S ~ U ~ A Z ~ S
Ayla GULEKON. M.D..
Canan KEVLEKCi. M.D..
Mehtnet Ali GURER, M.D.
Gazi University Faculty of Medicine, Department of Dermatoloa, Ankara, 'hrkey
Gazi Medical Journal 2004; 15: 79-81
oreas. The lors of melanocyler on pronulrc
oi$ci~rc sanmnkrayri. Prririorrk
ienonr, any psortorrc lerrons on nonnol skin in our polrenf
yuklufi<, vrrdrpnlrr nlonlur drlindah7 normal derrdc psdna1,k
wirh vrrrbpv, ond the effielivenesr of uilralnolrl lipllr on
oimurnou ve psdrrmisre uirrasiyololin eth~n/,,<!:
psortorcr indicared lhar melonocyle may play 61 role in
niel~mosirlenn, psdrlazlsle eprdermnl reyiiloi~ondu rol
rpzdermal regulatron m psoriarcr.
~lnnbmr Kimeler: Psiinons: VioBfo: (Jto~,~mnnire.
\\ere nonnal or nepative. The tl~vroid was
Vttiligo is a msorder characterized by Uie loss
of melanocytes from the epidermis. and is
associated with autoimmune diseases such as
thyroid disease, diabetes mellil~~s,
areata. pernicious anemia. and autoi~nmune
polyglandular syndrome. Vitiligo is related to
organ-specific autoantibodies such as parietal.
adrenal, and thymid-(related) antibodies (I), and
antimelanocyte antibodies such as antityrosinase.
and antityrosinase related proteins I and 2
antibodies (2). These antibodies inmcate vitiligo
to be an autoin~mune disease.
A 50-year-old caucasian man. with a 7-year
thymglobulin ntes were high. Both lobes we1.e
Iicterogeneous and larger than nonnal on Ulyroid
ultnsound. Based on these results we made a
diagnosis of Haslunloto's thy miditis.
On physical examination, large depiglnented
areas on the skin of the elbow. clun. l~and orsun~
and scrotunl were obsewed (Fig. I and 2).
Papulosquamous eruptions were confined to the
nonpig~ncnted areas and psoriatic lesions wen: