ADULT CELLS successfully TREAT HUMANS with diabetes:
2005 Islet cells can be donated from live donors for patients, opening up many more transplant
possibilities. Using this technique, a mother donated cells for her diabetic daughter,
alleviating the diabetic symptoms. Matsumota S et al., Insulin independence after living-donor
distal pancreatectomy and islet allotransplantation, The Lancet, 365, 1642-1644, 7 May 2005.
2001 The Edmonton protocol was used to isolate cadaveric islet cells to treat 12 people with
juvenile diabetes. Ryan A. et al., Glycemic Outcome Post Islet Transplantation, Annual Meeting of
the American Diabetes Association, June 22-26, 2001. Since 2001, over 200 diabetic patients
have been treated with this protocol.
ADULT STEM CELLS successfully TREAT diabetes in MICE:
2006 Tulane researchers showed that human bone marrow adult stem cells restored normal insulin
secretion and blood sugar in mice, and promoted repair of both pancreas and kidney tissue.
Lee RH et al., Multipotent stromal cells from human marrow home to and promote repair of
pancreatic islets and renal glomeruli in diabetic NOD/scid mice, Proceedings of the National
Academy of Sciences USA 103, 17438-17443, November 14, 2006.
2006 Three independent studies confirmed earlier findings by Harvard researchers that blocking
autoimmune attack on the diabetic pancreas leads to regeneration of insulin-secreting cells
in diabetic mice. Chong AS et al., Reversal of diabetes in non-obese diabetic mice without spleen
cell-derived β cell regeneration, Science 311, 1774-1775, March 24, 2006; Nishio J et al., Islet
recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell
contribution, Science 311, 1775-1778, March 24, 2006; Suri A et al., Immunological reversal of
autoimmune diabetes without hematopoietic replacement of β cells, Science 311, 1778-1780, March
2006 NIH scientists showed that they could grow pancr