Indian J Med Res 131, May 2010, pp 636-640
Diabetes mellitus (DM) are a group of metabolic
disorders that share the common phenotype of
hyperglycemia, polydipsia, polyuria and polyphagia.
Although peripheral and autonomic neuropathy is a
common complication of DM, the central nervous
system (CNS) does not seem to be spared either. In the
past few years, CNS involvement in DM has received a
special attention, particularly the higher brain functions.
Effect of pranayama & yoga-asana on cognitive brain functions in
type 2 diabetes-P3 event related evoked potential (ERP)
tenzin Kyizom, Savita Singh, K.P. Singh*, O.P. tandon & Rahul Kumar
Departments of Physiology & *Medicine, University College of Medical Sciences & Guru Teg Bahadur Hospital
Received December 12, 2008
Background & objectives: Electrophysiological evidence of delayed cognition as measured by P300, an
evoked potential is observed in Diabetes mellitus. P300 (or P3) is a component of endogenous cerebral
evoked response that assesses higher functions of the brain. Our study aims to see the role of pranayama
and yoga-asana on P300 latency and amplitude in type 2 diabetic patients.
Methods: Sixty patients of type 2 diabetes were recruited from diabetic clinic and divided into two groups
- control group on only conventional medical therapy and yoga-group on conventional medical therapy
along with pranayama and yoga-asana. Basal recordings of P300 and blood glucose were taken at the
time of recruitment and second recordings repeated after forty five days for both the groups. P300 was
recorded on Nihon Kohden Neuropack μ MEB 9100 using auditory “odd-ball paradigm”. The data were
analysed using repeated measures analysis of variance (ANOVA) followed by Tukey’s test at 5 per cent
level of significance.
Results: Statistically significant improvement in the latency and the amplitude of N200, P300 was
observed in the yoga group as compared to the control group.
Interpretation & conclusions: Our data suggest that yoga has a