Electron J Biomed 2009;1:10. Arora et al... MULTIPURPOSE SOLUTION ON HYDROPHILIC CONTACT LENSES
Normas para los
Derechos de autor
DEPOSITION STUDIES USING
MULTIPURPOSE SOLUTION ON
HYDROPHILIC CONTACT LENSES
A. Arora1, A. Ali2, R. K. Khar2, M.T. Zzaman1.
1Kiet School of Pharmacy. Ghaziabad-Meerut Road. Ghaziabad
2Department of Pharmaceutics. Faculty of Pharmacy. Jamia Hamdard, Hamdard Nagar.
New Delhi. India
alkamailin @ yahoo.co.in
Rev Electron Biomed / Electron J Biomed 2009;1:10-17
Comment of the reviewer Prof. Pilar Muñiz Rodriguez. PhD. Professor of Biochemistry and Molecular Biology, Faculty of
Science. University of Burgos. España
Comment of the reviewer Victoria Valls Bellver PhD. Biochemistry. Department of Pediatry and Ginecology. University of
In the tears lysozyme and albumin are also present besides other constituents. All these constituents form a biofilm on the
hydrophilic contact lenses - minutes after the lens is placed in the eye. These deposits if not removed make the contact lens
translucent and impair visual acuity. For the removal of deposit multipurpose solution is used.
In the study, deposits of lysozyme and albumin were made on hydrophilic contact lenses deliberately. These deposits laden
contact lenses were then treated with multipurpose solution for 12 hrs. The extent of removal of these deposits by the action of
sodium citrate present in multipurpose solution was assessed by measuring albumin and lysozyme quantitatively by using
standard analytical procedures.
It was observed that 0.1% of sodium citrate could remove lysozyme and albumin efficiently. Albumin deposited more as
compared to lysozyme and non ionic hydrophilic contact lenses are less prone to deposition than ionic. Any further increase in
sodium citrate was not desirable.