Patient Care and Medical Knowledge
Resources
Utilize the extensive resources electronic, paper-based, and person-based (physician
consult services, social work, nursing, pharmacy, practice management, other allied health care
professionals) available to help residents taking care of patients with nephrology related
problems.
Core Knowledge
• Demonstrate ability to use the serum creatinine concentration to estimate Glomerular
Filtration Rate.
• Explain the assumption of steady-state concentration
• Discuss shortcomings of creatinine-based methods of estimating GFR
• Demonstrate ability to interpret a spot protein-to-creatinine ratio and/or a spot albumin-
to-creatinine ratio on a random urine sample as a marker of kidney damage and a
quantitative measure of protenuia
• Relate this test to 24-hour urine results.
• Recognize that 24 hour urine collections for the purposes of
1. GFR estimation from creatinine clearance
2. Diagnosing and following proteinuria are not superior to the spot tests above (in the
majority of situations
• Know the patient population at risk for chronic kidney disease
• Discuss risk factors for acute renal failure in out- and in-patient settings
• Categorize based on both frequency of occurrence and on dominant Pathological site(s)
of injury. (Pre-renal, Intra-renal [includes vascular, glomerular, tubular and interstitial]
and Post-renal) the causes of
- Chronic Kidney Disease
- Acute Renal Failure
• Define and List the most common causes of:
- Nephrotic syndrome
- Rapidly progressive glomerulonephritis
• Define and List the most common causes of
- Isolated hematuria (i.e. without other abnormalities)
- Isolated proteinuria (i.e. without other abnormalities)
- Hematuria and proteinuria without a decreased GFR
• Discuss the physiological concept of clearance and apply this to: Native renal function
(GFR) and, Principles governing solute clearance by peritoneal dial