Home / Medicinal Chemistry
/ Library Design
A well-designed compound library contains a broad range of truly stored chemicals and/or virtual compounds,
which can meet majority requirements and truly jump-start the search for new drugs. In addition, such compound
library or chemical library is able to provide comprehensive associated data of the stored chemicals, including
chemical structure, purity, quantity, and physicochemical properties. Generally, a compound library is mainly
composed of a series of 2D or 3D representations of compounds, which can be applied for various purpose
through computational approaches. In order to increase the screening success rate and reduce unnecessary costs,
different screening strategies have been developed and widely used. According to the design purpose, the
screening strategies can be roughly divided into two types: positive design and negative design.
Figure1. Negative design and positive design screening concept diagram(Yang, Z.Y.; et al. 2020)
An experienced team that can quickly produce a variety of compounds.
Our well-trained team has extensive experience in chemical methodology development and total synthesis of
natural products; our team often works on complex heterocyclic compounds, polycyclic compounds and chiral
We can quickly produce a variety of compounds through the discovery and development of chemical scaffolds,
parallel synthesis methods, MPLC/HPLC purification systems, and chiral separation processes.
BOC Sciences’ extensive technology and expertise accelerate our customers’ synthetic aperture radar research
* Services & Products Interested
Please input project description
* Verification Code
and contribute to their drug development