EXHIBIT 10.21
CONFIDENTIAL
SEPARATION AGREEMENT AND RELEASE
This Separation Agreement and Release (hereafter "Agreement") is entered into by and between Arena
Pharmaceuticals, Inc. (hereafter, as defined below, "Company") and Richard P. Burgoon, Jr. (hereafter
"Executive"), an individual who resides in California. As used in this Agreement, "Company" shall include and
encompass all of the past, present, or future parent, affiliated, related and/or subsidiary companies of Arena
Pharmaceuticals, Inc. (including without limitation ChemNavigator.com, Inc., Aressa Pharmaceuticals, Inc. and
BRL Screening, Inc.), and their past, present, and future directors, shareholders, officers, employees, agents,
attorneys and representatives. In consideration of the mutual promises and undertakings of the parties, it is agreed
as follows:
1. FINAL DAY OF EMPLOYMENT. Executive's final day of employment with the Company is September 30,
2001 (the "Separation Date"). Executive hereby resigns as an officer and director, as applicable, of the
Company, including, without limitation, ChemNavigator.com, Inc., as of September 30, 2001. Following this
date, Executive shall cease to be employed by the Company in any capacity, and shall cease to be an officer
and/or director of the Company. In addition, Executive's Services Agreement with Chemnavigator.com, Inc. (the
"Services Agreement"), a true and correct copy of which is attached hereto as Exhibit "A", shall terminate
effective the Separation Date.
2. PAYMENT. In consideration for the release provided in Paragraph 4 and the performance of the consulting
services identified in paragraph 8 below, following the Company's receipt of a fully executed copy of this
Agreement and the expiration of the revocation period identified in paragraph 13 below, the Company will:
Pay Executive through November 15, 2001 severance pay in an amount equivalent to Executive's regular weekly
salary as of the Separation Date. Such payment shall be made on those days Executive would hav