A project of the New Mexico AIDS Education and Training Center. Partially funded by the National Library of Medicine
Fact Sheets can be downloaded from the Internet at http://www.aidsinfonet.org
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Fact Sheet Number 421
TRUVADA (Tenofovir + Emtricitabine)
WHAT IS TRUVADA?
Truvada is a pill that contains two drugs
used to fight HIV: Tenofovir (Viread) and
manufactured by Gilead Sciences.
in Truvada are called
nucleoside analog reverse transcriptase
inhibitors, or nukes. These drugs block
the reverse transcriptase enzyme. This
enzyme changes HIV’s genetic material
(RNA) into the form of DNA. This has to
occur before HIV’s genetic code gets
inserted into an infected cell’s own
Truvada was approved in 2004 for people
with HIV infection. It has not been
carefully studied in children or older
There are no absolute rules about when
to start antiretroviral therapy (ART). You
and your health care provider should
consider your CD4 cell count, your viral
load, any symptoms you are having, and
your attitude about taking ART. Fact
Sheet 404 has more information about
guidelines for the use of ART.
take Truvada with
antiretroviral drugs (ARVs), you can
reduce your viral load to extremely low
levels, and increase your CD4 cell counts.
This should mean staying healthier
Truvada has not been tested in people
under 18 years old and people who have
hepatitis B infection. They should not take
Truvada without careful discussion with
their health care provider.
Some people with HIV had their hepatitis
B get worse after they stopped taking
emtricitabine, which is part of Truvada.
Get tested for hepatitis B before you start
taking Truvada to treat HIV. If you have
hepatitis B and stop taking Truvada, your
health care provider should carefully
monitor your liver function for several