ORACLE USA, INC.
PAIN THERAPEUTICS, INC.
2211 Bridgepointe Parkway,
San Mateo, California
(“Bridgepointe Building 2”)
THIS SUBLEASE (“Sublease”) is entered into as of July 7, 2007, by and between ORACLE USA, INC., a Colorado corporation
(“Sublandlord”), and PAIN THERAPEUTICS, INC., a Delaware corporation (“Subtenant”), with reference to the following facts:
A. Pursuant to that certain Lease dated as of March 11, 1999 (the “Original Master Lease”), as the same has been amended
by that certain First Amendment to Lease dated as of June 11, 1999 (the “First Amendment”), by that certain Second
Amendment to Lease dated as of July 31, 2000 (the “Second Amendment”) and by that certain Third Amendment to Lease dated
as of August 11, 2006 (the “Third Amendment”) (the Original Master Lease, as amended by the First Amendment, the Second
Amendment and the Third Amendment, being referred to herein as the “Master Lease”), Sobrato Interests III (“Landlord”), as
Landlord, leases to Sublandlord (successor in interest to Siebel Systems, Inc.), as tenant, certain space (the “Master Lease
Premises”) consisting of the entire 141,496 rentable square foot building located at 2211 Bridgepointe Parkway (“Building 2” or
the “Building”) in the City of San Mateo (“City”), State of California. The Building, together with (i) the 141,496 rentable square
foot building located at 2215 Bridgepointe Parkway (“Building 1”) and (ii) the 167,505 rentable square foot building located at
2207 Bridgepointe Parkway (“Building 3”) comprise the “Project,” as more particularly defined in the Master Lease. Pursuant to
separate leases, Sublandlord has leased all of Building 1 and all of Building 3.
B. Subtenant wishes to sublease from Sublandlord, and Sublandlord wishes to sublease to Subtenant, a portion of the
Master Lease Premises containing approximately 30,718 rentable square feet located on the fifth (5th) floor of the Building, said
space being more particular