he Colon Cancer Family Registry
(CFR) has had an exciting year of research.
In fact, the Colon CFR is facilitating over
125 approved research projects, which
include major collaborations with over a
dozen of the best colorectal cancer research
groups in the world. Here’s a quick
overview:
First, it’s clear that
genetic factors can be
important causes of
colorectal cancer. The
Colon CFR is involved
in world-wide, collabo-
rative studies to identify
new genes that may cause colorectal cancer.
This past year, these collaborative
studies identified two regions, on chromo-
somes #8 and #9, where there is consistent
evidence that genes in these regions may
increase the risk of getting colorectal
cancer. Of interest, the region on chromo-
some #8 is also associated with prostate
COLON CANCER FAMILY REGISTRY
We ARE Making Progress
in the Fight Against
Colorectal Cancer
FALL-WINTER 2007
VOLUME 5, NO. 1
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USC CONSORTIUM: Dartmouth Medical School — Cleveland Clinic Foundation — University of Arizona
University of Colorado — University of Minnesota — University of North Carolina — University of So. California
The CFR Celebrates 10 Years and Plans for the Future!
he Colon Cancer Family Registry (CFR) is 10 years old and has
grown into one of the largest resources available to researchers
studying colon cancer! The international CFR has enrolled 13,460
families and 34620 individuals and of these, 1775 families and 4577
individuals have joined through the USC Consortium.
In this issue, we focus on the history of the CFR — where we started,
how we’ve grown and what we’ve accomplished — as well as exciting new research
being undertaken. The Colon CFR has become an outstanding resource that you
helped build — Thank you!
and breast cancer. The hunt is now on to
identify the exact genes in these two
regions that may cause colorectal cancer.
Also, the
National Cancer
Institute funded
the Colon CFR to
conduct a study to
sc