TO CREDIT AGREEMENT
This FOURTH AMENDMENT TO CREDIT AGREEMENT (this "Fourth Amendment") is dated as of June
24, 1994 and entered into by and among Amgen Inc., a Delaware corporation (the "Company"), the subsidiaries
of the Company signatory to the Credit Agreement defined below (together with the Company, the "Borrowers"),
Swiss Bank Corporation, San Francisco Branch, Citicorp USA, Inc., and each other lender whose name is set
forth on the signature pages of the Credit Agreement defined below (collectively, the "Banks"), Swiss Bank
Corporation, New York Branch as Issuing Bank (the "Issuing Bank"), and Swiss Bank Corporation, New York
Branch and Citicorp USA, Inc. as Co-Agents for the Banks (the "Co- Agents"). This Fourth Amendment
amends that certain Credit Agreement dated as of November 15, 1991, as amended by that certain First
Amendment to Credit Agreement dated as of June 16, 1992, that certain Second Amendment to Credit
Agreement dated as of November 6, 1992 and that certain Third Amendment to Credit Agreement dated as of
June 25, 1993 (as so amended, the "Credit Agreement") by and among the Borrowers, the Banks, the Issuing
Bank and the Co-Agents. Capitalized terms used herein without definition shall have the same meanings herein as
set forth in the Credit Agreement.
WHEREAS, the Borrowers, the Banks, the Issuing Bank and the Co-Agents desire to amend the Credit
Agreement as follows:
(i) to extend the maturity dates of the Tranche A-1 Commitment and the Tranche A-2 Commitment, (ii) to reduce
the commitment fees payable with respect to the Tranche A-1 Commitment and the Tranche A-2 Commitment,
and (iii) to reduce the interest rate spread applicable to Eurodollar Rate Advances.
NOW, THEREFORE, in consideration of the foregoing and the mutual covenants and agreements set forth
herein, the parties hereto agree as follows:
Section 1. AMENDMENTS TO SECTION 1 OF THE CREDIT AGREEMENT
(a) The table entitled "Rate Spread and LC Fees"