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Chloramphenicol HAZARD Product contact Eye Section skin irritant Page Chloramphenicol Page
Conforms to 93/112/EC and ISO 11014-1
Material Safety Data Sheet
Chloramphenicol
Not available.
0017808
CALL CHEMTREC:
800.424.9300
OUTSIDE US:
202.483.7616
11/4/2002
11/7/2002
Product name
Supplier
Manufacturer
Product No.
MSDS#
Validation Date
Print Date
In Case of Emergency
Section 1. Chemical Product and Company Identification
Responsible Name Pierce Administration
Synonyms ACETAMIDE, 2,2-DICHLORO-N-(2-HYDROXY-1-(HYDROXYMETHYL)-2-(4-NITROPHENYL)ETHYL)-,; ALFICETYN;
AMBOFEN; AMPHENICOL; AMPHICOL; AMSECLOR; AQUAMYCETIN; AUSTRACIL; AUSTRACOL; BIOCETIN;
BIOPHENICOL; CAF; CAM; CAP; CATILAN; CHEMICETIN; CHEMICETINA; CHLOMIN; CHLO MYCOL;
CHLORAMEX; CHLORAMPHENICOL; D-CHLORAMPHENICOL; D-THREO-CHLORAMPHENICOL;
D-(-)-THREO-CHLORAMPHENICOL; CHLORAMSAAR; CHLORASOL; CHLORA-TABS; CHLORICOL;
CHLOROAMPHENICOL; CHLOROCAPS; CHLOROCID; CHLOROCIDE; CHLOROCIDIN C; CHLOROCIDIN C
TETRAN; CHLOROCO L; CHLOROMYCETIN; CHLORONITRIN; CHLOROPTIC; CHLORO-25 VETAG;
CIDOCETINE; CIPLAMYCETIN; CLORAMFICIN; CLORAMICOL; CLORAMIDINA; CLOROAMFENICOLO (ITALIAN);
CLOROCYN; CLOROMISAN; CLOROSINTEX; COMYCETIN; CPH; CYLPHENICOL; DESPHEN; DETREOMYCINE;
DEXTROMYCETIN;  D-(-)-THREO-2-DICHLOROACETAMIDO-1-P-NITROPHENYL-1,3-PROPANEDIOL;
D-THREO-N-DICHLOROACETYL-1-P-NITROPHENYL-2-AMINO-1,3-PROPANEDIOL;
D-(-)-THREO-2,2-DICHLORO-N-(BETA-HYDROXY-ALPHA-(HYDROXYMETHYL))-P-NITROPHENETHYLACETAMIDE;
D-THREO-N-(1,1'-DIHYDROXY-1-P-NI TROPHENYLISOPROPYL)DICHLOROACETAMIDE; DOCTAMICINA;
ECONOCHLOR; EMBACETIN; EMETREN; ENICOL; ENTEROMYCETIN; ERBAPLAST; ERTILEN; FARMICETINA;
FENICOL; GLOBENICOL; GLOROUS; HALOMYCETIN; HORTFENICOL; I 337A; INTRAMYCETIN; ISICETIN;
ISMICETINA; ISOPHENICOL; IS OPTO FENICOL; JUVAMYCETIN; KAMAVER; KEMICETINA; KEMICETINE;
KLORITA; KLOROCID S; LEUKOMYAN; LEUKOMYCIN; LEVOMICETINA; LEVOMYCETIN; LOROMISAN;
LOROMISIN; MASTIPHEN; MEDIAMYCETINE; MICLORETIN; MICOCHLORINE; MICOCLORINA; MICROCETINA;
M Y C H E L
;
 M Y C
I N O L
;
 
N C
I
- C 5
 
5 7 0 9
;
D-(-)-THREO-1-P-NITROPHENYL-2-DICHLORACETAMIDO-1,3-PROPANEDIOL;
D-THREO-1-(P-NITROPHENYL)-2-(DICHLOROACETYLAMINO)-1,3-PROPANEDIOL; NORMIMYCIN V;
NOVOCHLOROCAP; NOVOMYCETIN; NOVOPHENICOL; NSC 3069; OFTALENT; OLEOMYCETIN; OPCLOR;
OPELOR; OPHTHOCHLOR;  OPHTOCHLOR; OTACHRON; OTOPHEN; PANTOVERNIL; PARAXIN;
PENTAMYCETIN; QUEMICETINA; RIVOMYCIN; ROMPHENIL; SEPTICOL; SIFICETINA; SINTOMICETINA;
SINTOMICETINE R; STANOMYCETIN; SYNTHOMYCETIN; SYNTHOMYCETINE; SYNTHOMYCINE; TEVCOCIN;
TEVCOSIN; TIFOMYCIN; TIFOMYC INE; TREOMICETINA; U-6062; UNIMYCETIN; VETICOL
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Eng
In USA: 
 In Europe:
Pierce 
 Perbio Science
P.O. Box 117 
 Industriezone III
Rockford, IL 61105  Industrielaan 27
USA 
 9320 Erembodegem-Aalst
815.968.0747 or
 Belgium
1.800.874.3723
 Tel:+32 53 83 44 04
 
 Fax:+32 53 83 76 38
Pierce Biotechnology
P.O. Box 117
Rockford, IL 61105
USA
815.968.0747 or
1.800.874.3723
1) Chloramphenicol
56-75-7
98-100
200-287-4
T
R36/37/38, R45
Ingredient Name
EC Number
CAS No.
R-Phrases
Substance/Preparation
Substance
%
Symbol
:
Section 2. Composition, Information on Ingredients
Continued on Next Page
Chloramphenicol
Page: 2/6
Physical/chemical hazards
Human health hazards
Environmental hazards Not applicable.
Irritating to eyes, respiratory system and skin.
May cause cancer.
Not applicable.
Absorbed through skin.  Eye contact.  Inhalation.  Ingestion.
Emergency Overview
Medical Conditions Aggravated
by Overexposure:
Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in one or
many human organs.
Not available.
Overexposure /Signs/Symptoms
Section 3. Hazards Identification
Routes of Entry
Potential Acute Health Effects
Carcinogenic Effects Data
See Toxicological Information (section 11)
Risk of cancer depends on duration and level of exposure.  Avoid contact with eyes, skin and clothing.  Avoid breathing
dust.  Keep container closed.  Use with adequate ventilation.  Wash thoroughly after handling.
Hazardous in case of skin contact (irritant), of eye contact (irritant), of inhalation (lung irritant).
CARCINOGENIC EFFECTS: Classified 2A (Probable for human.) by IARC.  Classified None. by NIOSH.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
Review the most current and approved institutional guideline, protocol, standard operating procedure(s) and MSDS(s)
for the proper handling of institutional materials/equipment associated with the use of this product.
WARNING!
SUSPECT CANCER HAZARD.
MAY CAUSE CANCER.
CAUSES DAMAGE TO THE FOLLOWING ORGANS: LIVER, SKIN, EYES, BONE
MARROW.
MAY CAUSE RESPIRATORY TRACT, EYE AND SKIN IRRITATION.
Classification R36/37/38, R45
United States
Europe
Do NOT induce vomiting unless directed to do so by medical personnel.  Never give anything by mouth to an unconscious
person.  Loosen tight clothing such as a collar, tie, belt or waistband.  Get medical attention if symptoms appear.
Skin Contact
Ingestion
Check for and remove any contact lenses.  In case of contact, immediately flush eyes with plenty of water for at least 15
minutes.  Cold water may be used.  WARM water MUST be used.  Get medical attention.
In case of contact, immediately flush skin with plenty of water.  Cover the irritated skin with an emollient.  Remove
contaminated clothing and shoes.  Wash clothing before reuse.  Thoroughly clean shoes before reuse.  Get medical
attention.
Hazardous in case of inhalation (lung irritant).
Not available.
Hazardous in case of skin contact (irritant).  Skin inflammation is characterized by itching, scaling, reddening, or,
occasionally, blistering.
Skin Contact
Hazardous in case of eye contact (irritant).
Eye Contact
Inhalation
Aggravating conditions Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in one or many
human organs.
First-Aid Measures
If inhaled, remove to fresh air.  If not breathing, give artificial respiration.  If breathing is difficult, give oxygen.  Get medical
attention.
Notes to Physician Not available.
Not available.
Protection of first-aiders
Ingestion
Effects and symptoms
Inhalation
Eye Contact
Section 4. First Aid Measures
Notice to Reader Get immediate medical attention.
Continued on Next Page
Chloramphenicol
Page: 3/6
Hazardous thermal (de)composition
products
These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenated compounds.
May be combustible at high temperature.
Not available.
SMALL FIRE:  Use DRY chemical powder.
LARGE FIRE:  Use water spray, fog or foam.  Do not use water jet.
Not available.
Section 5. Fire Fighting Measures
Flammability of the Product
Flash Points
Fire Hazards in Presence of Various
Substances
Fire Fighting Media
and Instructions
Be sure to use an approved/certified respirator or equivalent.
Protective Clothing (Fire)
Use a shovel to put the material into a convenient waste disposal container.  Finish cleaning by spreading water on the
contaminated surface and allow to evacuate through the sanitary system.  Be careful that the product is not present at a
concentration level above TLV.  Check TLV on the MSDS and with local authorities.
Section 6. Accidental Release Measures
Small Spill and Leak Use appropriate tools to put the spilled solid in a convenient waste disposal container.  Finish cleaning by spreading
water on the contaminated surface and dispose of according to local and regional authority requirements.
Environmental Precautions and
Clean-up Methods
Personal precautions Splash goggles.  Lab coat.  Dust respirator.  Be sure to use an approved/certified respirator or equivalent.  Gloves.
Keep container tightly closed.  Keep container in a cool, well-ventilated area.
Avoid contact with eyes, skin, and clothing.  Avoid breathing dust.  Keep container closed.  Use with adequate
ventilation.  Wash thoroughly after handling.
Section 7. Handling and Storage
Handling
Storage
Suitable /  Not suitable
Packaging materials
Use original container.
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
1) Chloramphenicol
Not available.
Netherlands
1) Chloramphenicol
Not available.
France
1) Chloramphenicol
Not available.
Norway
1) Chloramphenicol
Not available.
Denmark
1) Chloramphenicol
Not available.
Sweden
1) Chloramphenicol
Not available.
United States
Ingredient Name
Occupational Exposure Limits
Engineering Controls Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits.  If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Section 8. Exposure Controls/Personal Protection
Exposure Limit Values
Continued on Next Page
Chloramphenicol
Page: 4/6
1) Chloramphenicol
Not available.
Germany
Personal Protection
Eyes
Body
Hands
Protective Clothing
(Pictograms)
Gloves.
Lab coat.
Splash goggles.
Respiratory Respirator is not needed under normal and intended conditions of use, if exposures are kept below established limits.
Solid. (NEEDLES OR ELONGATED
PLATES FROM WATER OR ETHYLENE
DICHLORIDE)
150.55°C (303°F)
Not available.
Very slightly soluble in cold water, hot water.
323.2 g/mole
Not available.
Bitter.
Grey.  White to yellowish.
Melting/Freezing Point
Physical State  and
Appearance
Molecular Weight
Dispersion Properties
Solubility
Odor
Taste
Color
C11H12Cl2N2O5
Molecular Formula
Section 9. Physical and Chemical Properties
The product is stable.
Not available.
Will not occur.
Not available.
Section 10. Stability and Reactivity
Stability and Reactivity
Conditions to avoid
Materials to avoid
Hazardous Polymerization
Hazardous Decomposition
Products
These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenated compounds.
Acute oral toxicity (LD50): 500 mg/kg [Guinea pig].
Hazardous in case of eye contact (irritant), of inhalation (lung irritant).
CARCINOGENIC EFFECTS: Classified 2A (Probable for human.) by IARC.  Classified None. by NIOSH.
Causes damage to the following organs: liver, skin, eyes, bone marrow.
Not available.
Not available.
Not available.
Section 11. Toxicological Information
Toxicity to Animals
Chronic Effects on Humans
Other Toxic Effects on Humans
Special Remarks on Toxicity to
Animals
Special Remarks on Chronic
Effects on Humans
Special Remarks on Other Toxic
Effects on Humans
Continued on Next Page
Chloramphenicol
Page: 5/6
Ecotoxicity Not available.
Mobility
Germany water class
Not available.
Not available.
Not available.
Persistence/degradability
Bioaccumulative potential
VCI WGK: No products were found.
Section 12. Ecological Information
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Not available.
Waste Information
Waste Stream
Section 13. Disposal Considerations
Consult your local or regional authorities.
Contact the supplier for all information regarding the proper transportation method for this material.
Section 14. Transport Information
U.S. Federal Regulations
Irritating substance.
HCS Classification
Section 15. Regulatory Information
TSCA 8(b) inventory: Chloramphenicol
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
WHMIS (Canada) CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).
CLASS D-2A: Material causing other toxic effects (VERY TOXIC).
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: Chloramphenicol
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: Chloramphenicol: delayed health hazard
SARA 313 toxic chemical notification and release reporting: No products were found.
R36/37/38- Irritating to eyes, respiratory system and skin.
R45- May cause cancer.
S2- Keep out of the reach of children.
S46- If swallowed, seek medical advice immediately and show this container or label.
S53- Avoid exposure - obtain special instructions before use.
Toxic
Label Requirements
(Europe)
1
Continued on Next Page
Chloramphenicol
Page: 6/6
Pennsylvania RTK: Chloramphenicol: (special hazard, generic environmental hazard)
Massachusetts RTK: Chloramphenicol
New Jersey: Chloramphenicol
California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer, birth defects or other
reproductive harm, which would require a warning under the statute: Chloramphenicol
California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer which would require
a warning under the statute: Chloramphenicol
State Regulations
CEPA DSL: Chloramphenicol
Australia (NICNAS): Chloramphenicol
VCI WGK: No products were found.
Korea (TCCL): Chloramphenicol
Philippines (RA6969): Chloramphenicol
R36/37/38- Irritating to eyes, respiratory system and skin.
R45- May cause cancer.
DSCL (EEC)
International Regulations
Not available.
EINECS
International Lists
Version
0.01
Date of Previous Issue No Previous
Validation
Not available.
Section 16. Other Information
References
Validated by Pierce Administration on 11/4/2002.
Verified by Pierce Administration.
Printed 11/7/2002.
Notice to Reader
To the best of our knowledge, the information contained herein is accurate.  However, neither the above named supplier nor any of its subsidiaries assumes any
liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution.
Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.
Hazardous Material
Information System
(U.S.A.)
1
0
0
E
0
0
1
*
National Fire Protection
Association (U.S.A.)
Health
Specific Hazard
Reactivity
Fire Hazard
Health
Fire Hazard
Reactivity
Personal Protection
History of Document Changes Any information changes since last document version are marked with a triangle symbol.
Irritating to eyes, respiratory system and skin.
May cause cancer.
Full text of R-Phrases
referenced under headings 2 and 3:
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.