Kumar et al
Trop J Pharm Res, June 2007; 6 (2)
Tropical Journal of Pharmaceutical Research, June 2007; 6 (2): 717-723
© Pharmacotherapy Group,
Faculty of Pharmacy, University of Benin,
Benin City, Nigeria.
All rights reserved.
Available online at http://www.tjpr.org
Antimicrobial effects of Indian medicinal plants
against acne-inducing bacteria
GS Kumar1*, KN Jayaveera2, CK Ashok Kumar3, Umachigi P
Sanjay4, BM Vrushabendra Swamy5, DV Kishore Kumar6.
1Department of Chemistry (K.N.J) Jawaharlal Nehru Technological University College of Engineering, Ananthpur- 01,
Andhra Pradesh, India. 2Department of Pharmacognosy (G.S.K), 3Department of Pharmaceutics (U.P.S),
4Department of Pharmacology (B.M.V.S), 5Department of Chemistry (D.V K.K), Rural College of Pharmacy,
D.S.Road, Devanahalli-562110 Karnataka, India. 6Department of Pharmacognosy (A.K.C.K) Sree Vidyanikethan,
College of Pharmacy, A.Rangamepeta, Chittoor Dist, Andhra Pradesh, India.
Propionibacterium acnes and Staphylococcus epidermidis have been recognized as pus-forming
bacteria triggering an inflammation in acne. The present study was conducted to evaluate antimicrobial
activities of Indian medicinal plants against these etiologic agents of acne vulgaris. Ethanolic extracts of
Hemidesmus indicus (roots), Eclipta alba (fruits), Coscinium fenestratum (stems), Curcubito pepo
(seeds), Tephrosia purpurea (roots), Mentha piperita (leaves), Pongamia pinnata (seeds), Symplocos
racemosa (barks), Euphorbia hirta (roots), Tinospora cordyfolia (roots), Thespesia populnea (roots), and
Jasminum officinale (flowers) were tested for antimicrobial activities by disc diffusion and broth dilution
methods. The results from the disc diffusion method showed that 07 medicinal plants could inhibit the
growth of Propionibacterium acnes. Among those Hemidesmus indicus, Coscinium fenestratum,
Tephrosia purpurea, Euphorbia hirta, Symplocos racemosa, Curcubito pepo and Eclipta alba had strong