THIS LEASE , Made this 1st day of March 2004, by and between MIE Properties, Inc. as agent for
owner, herein called “Landlord”, and BBI Biotech Research Laboratories, Inc., herein called “Tenant”.
WITNESSETH , that in consideration of the rental hereinafter agreed upon and the performance of all
the conditions and covenants hereinafter set forth on the part of Tenant to be performed, Landlord does hereby
lease unto said Tenant, and the latter does lease from the former an agreed upon 65,160 square feet at the
following premises: 8425 Progress Drive, Suites A-Y, Frederick, Maryland 21701, (herein called the
“Premises”) for the term of Eleven (11) years, beginning on the Rent Commencement Date (as defined
below) and ending on the 31st day of July 2015, for the annual rental of see Rent schedule below , (herein
called “Annual Rent”), subject to Annual Rent increases payable in advance beginning on the Rent
Commencement Date (as defined below) and on the first day of each and every month thereafter during the term
of this Lease in equal monthly installments of see rent schedule below (provided that such installments shall
be prorated in the case of any partial month) .
For the first year of the lease term, Tenant will occupy and use 39,120 square feet of the Premises and
commencing on August 1, 2005, Tenant will occupy and use the entire 65,160 square feet of the Premises.
Said installments of Annual Rent shall be paid to MIE Properties. Inc. , 5104 Pegasus Court. Suite
A, Frederick, Maryland 21704, or at such other place or to such appointee of Landlord, as Landlord may
from time to time designate in writing.
TENANT COVENANTS AND AGREES WITH LANDLORD AS FOLLOWS:
1. Tenant shall pay said rent and each installment of Annual Rent thereof as and when due without
setoff or deduction. Installments of Annual Rent and Additional Rent (as defined in paragraph 4 hereof) shall
become due on the earlier of (i) 30 days after Tenant gives Landlord w