Soriatane (acitretin) Flowsheet Patient Name:_____________________ Start Date: ___________
Indication: Severe psoriasis in adults: ___generalized pustular ___erythrodermic ___severe recalcitrant ___severe plaque
Off Label uses: ___Darier’s ___PRP ___Lupus ___chemoprevention of malignancies Other: _____________________
Contraindications: Absolute: ___ Pregnancy or a woman who is likely to become pregnant or who intend to become
pregnant within 3 years following cessation of treatment with acitretin.
___Females who cannot use reliable contraception while undergoing treatment and for
at least 3 years after d/c of acitretin
___ Noncompliance with contraception
___ Nursing mothers
___Concurrent use of methotrexate (increased liver toxicity) or tetracyclines (pseudotumor cerebri)
___Moderate to severe chol or trig elevation
___Sig. hepatic dysfunction
___Sig. renal dysfunction
Precautions: ___Alcohol consumption will cause acitretin (half-life 2 days) to be metabolized to etretinate (half-life 120days and
has been found in serum up to 4 years & 4 months- after d/c).
Supplied as: 10 and 25mg capsules.
Dosing: Not based on body weight. Start at 25mg/day and increase. Psoriasis clears faster at higher initial starting doses, but hair
loss and paronychia occur more frequently. For psoriasis: 20-50mg/d mainten