Chronic Myelogenous
Leukemia (CML)
Hematology Practice Guideline
Dr. Anargyros Xenocostas, MD, FRCPC (Hematology Consultant)
Approval Date:
September 2007
This guideline is a statement of consensus of the Hematology Disease Site Team regarding
their views of currently accepted approaches to treatment. It is not intended to replace the
independent medical judgment of the physician in the context of individual clinical
circumstances to determine any patient’s care or treatment.
Table of Contents
1. Background/Overview ...................................................................................
2
2. Treatment Guidelines.....................................................................................
3
3. Attachment #1: Treatment Algorithm............................................................
3
4. Attachment #2: Guideline Summary ............................................................
4
5. Reference .......................................................................................................
8
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Chronic Myelogenous Leukemia - Hematology Practice Guideline
Background/Overview
The Hematology Disease Site Team has and will be following the Guidelines recently
published by the Canadian Consensus Group1 with respect to the diagnosis, treatment
and follow-up of patients with CML. This is summarized in a patient care flowchart
(Attachment #1).
An updated summary of the guidelines can be found at:
URL: http://cmlrecommendations.ca
ID: cmlcases
PASSWORD: online
A copy of the Summary of Recommendations is appended (Attachment #2).
Differences between the Canadian Recommendations and our current practice at the
LRCC are highlighted (in blue font) after each of the ten recommendations.
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Chronic Myelogenous Leukemia - Hematology Practice Guideline
Treatment
Attachment #1: Patient Treatment Algorithm
Patient Evaluation
Bone marrow aspirate & biopsy
Diagnosis of CML