AMENDMENT TO LOAN AGREEMENT
THIS AMENDMENT TO LOAN AGREEMENT is made as of August 15, 2008, by and between
EMERGENT BIODEFENSE OPERATIONS LANSING INC. , a Michigan corporation, of Lansing, Michigan ("
Borrower "), and FIFTH THIRD BANK , a Michigan banking corporation, having an office in Grand Rapids,
Michigan (" Lender ").
Borrower and Lender are parties to a Loan Agreement dated June 8, 2007, under which Lender extended
to Borrower a revolving line of credit (" Agreement "). They want to amend the Agreement.
1. Section 1 of the Agreement is amended, effectively immediately, by adding to it the following
2. Effective immediately, Section 3 of the Agreement is amended in its entirety to read as follows:
SECTION 3. REVOLVING LINE OF CREDIT .
3.1 Subject to satisfaction of the conditions precedent set forth in Section 10 of this
Agreement, and as long as there shall not have occurred a Default or Event of Default, Lender shall
extend to Borrower from time to time loans (“ Revolving Credit Loans ”) and shall issue Letters of
Credit for the account of Borrower (“ Letters of Credit ”), in amounts that shall not at any time in the
aggregate, for all Revolving Credit Loans and Letters of Credit outstanding at any time, exceed the
Revolving Credit Commitment.
3.2 If the aggregate principal amount of the Revolving Credit Loans and Letters of Credit
outstanding at any time exceeds the Revolving Credit Commitment, then Borrower shall immediately
take whatever action is required to eliminate the excess.
3.3 If the aggregate principal amount of Letters of Credit outstanding at any time exceeds
the Letter of Credit Commitment, then Borrower shall immediately take whatever action is required to
eliminate the excess.
3.4 All Revolving Credit Loans shall be evidenced by and payable with interest in
accordance with the terms of the promissory note in the form of S