STOCK OPTION PLAN
NON-QUALIFIED STOCK OPTION AGREEMENT
ViroPharma Incorporated (the "Company") hereby grants to Robert J. Glaser (the "Optionee") an option to
purchase a total of 20,000 shares of Common Stock of the Company, at the price and on the terms set forth
herein, and in all respects subject to the terms, definitions and provisions of the ViroPharma Incorporated Stock
Option Plan (the "Plan") applicable to non-qualified stock options, which terms and provisions are hereby
incorporated by reference herein. Unless the context herein otherwise requires, the terms defined in the Plan shall
have the same meanings when used herein.
1. NATURE OF THE OPTION. This Option is intended to be a nonstatutory stock option and is not intended
to be an Incentive Stock Option within the meaning of section 422 of the Internal Revenue Code of 1986, as
amended (the "Code"), or to otherwise qualify for any special tax benefits to the Optionee.
2. DATE OF GRANT; TERM OF OPTION. This Option is granted this 10th day of September, 1998, and it
may not be exercised later than July 30, 2007 subject to earlier termination, as provided in the Plan.
3. OPTION EXERCISE PRICE. The Option exercise price is $15.125 per Share.
4. EXERCISE OF OPTION. This Option shall be exercisable during its term only in accordance with the terms
and provisions of the Plan and this Option Agreement as follows:
(A) RIGHT TO EXERCISE. This Option shall vest and be exercisable as follows:
Vesting Date Number of Shares Vesting
(B) METHOD OF EXERCISE. This Option shall be exercisable during its term by written notice which shall
state the election to exercise this Option, the number of full Shares in respect to which this Option is being
exercised and which shall contain or be accompanied by such other representations and agreements as to the
Optionee's investment intent with respect to such Shares as may be reasonably required by the Company as
contemplated by the Plan. Such written n