Umaporn Chantbuddhiwet, MD
Queen Sirikit National Institute of Child Health
AIDS Situation in Thailand
1984
1987
1990
1993
Homosexual
IVDU
Commercial Sex worker
Male Heterosexual
Female Pregnant
Children
Percentage of AIDS patients by Age
1984-2008
(Bureau of Epidemiology, Department of Disease Control, MOPH)
Western &
Central Europe
3000
[2400 – 12 000]
Middle East & North
Africa
26 000
[19 000 – 34 000]
Sub-Saharan Africa
1.8 million
[1.7 – 2.1 million]
Eastern Europe
& Central Asia
9500
[6600 – 15 000]
South & South-East
Asia
140 000
[99 000 – 200 000]
Oceania
1100
[<2000]
North America
11 000
[4500 – 20 000]
Latin America
36 000
[31 000 – 47 000]
East Asia
7900
[5400 – 11 000]
Caribbean
11 000
[9200 – 12 000]
Children (<15 years) estimated to be living
with HIV, 2007
Total: 2.1 (1.9 – 2.4) million
0
500
1000
1500
19881989199019911992199319941995199619971998199920002001200220032004200520062007Total
Death
NumberofCasesNumber of Pediatric AIDS Cases, by Year of Onset, Thailand, 1988 - 2007
Fig 1
1
10
100
1000
10000
19881989199019911992199319941995199619971998199920002001200220032004200520062007Blood
Mothernal
Others
Unknown
Number of CasesNumber of Pediatric AIDS Cases, by Risk factor and Year of Onset, Thailand,
1988 - 2007
Fig 2
215 221
2
6
8
11
39
93
164
311
372
377
336
430 437
376
292
262
0
50
100
150
200
250
300
350
400
450
500
2532
2534
2536
2538
2540
2542
2544
2546
2548
AIDS
เริ่มให ARV ตัวเดียว AZT/ddI
เริ่มให ARV 2 ตัว
(โครงการศกึษาวิจัย)
เริ่มให ARV 3 ตัว
(โครงการ Acess to care)
เริ่ม นโยบาย PMTCT
เริ่ม GPO vir
(โครงการ NAPHA)
การใหการรักษาผูปวยติดเชื้อเอชไอวี
สถาบันสขุภาพเด็กแหงชาติมหาราชินี 2532-2549
Comparison of Children and Adult with
HIV infection
Children
• 20% have AIDS in 1st
year of life
•
(rapid progressor)
• 70% have AIDS by 4-6
years of age
• Higher baseline VL
• Lower virological
response rate to
HARRT
Adult
• Most are asymptomatic
for first 4-8 years
• AIDS defining illness in
6-10 years
• Lower baseline VL
• Higher virological
response rate to HARRT
Adul