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SA-50 BRAND DITHANE M-45R
MATERIAL SAFETY DATA SHEET
Souther Agricultural Insecticides, Inc.
P.O. Box 218, Palmetto, Fla. 34220
Re: Dithane M-45
Product Code 62433
I PRODUCT IDENTIFICATION
Product Name; SA--50 BRAND DITHANER M-45 EPA Reg No 829-286
Chemical Name: Mancozeb; A coordination product of zinc ion and manganese
Ethylenebisdithiocarbamate 80%, in which the ingredients are Manganese++ 16%,Zinc++ 2%,
Ethlenebisdithiocarbamate ion (C4H6N2S4) 62%
DITHANER is a trademark of Rohm and Haas Company or one of its subsidiaries or affiliates.
Cas Reg No.
Manganese in Mancozeb
5 mg/m3 (Mn) Table Z-1
Related reaction products . .
III HEALLTH HAZARDS
Primary Routes of Exposure
Inhalation: inhalation of dust can cause irritation of nose and throat.
Skin Contact :prolonged and repeated skin contact can cause possible skin irritation, dermatitis due to
sensitization, delayed effects.
Eye Contact: Direct contact can cause moderate irritation
Delayed effects: Mancozeb at high levels has caused hindleg paralysis in test animals and an increased
incidence of retinal degeneration. It has caused thyroid tumors and birth defects in test animals, resulting
from ethylenethiourea (ETU) formation. ETU, a trace contaminant and breakdown product of mancozeb,
primarily affects the thyroid and liver. It has also caused other endocrine and blood effects, tumors and birth
defects in test animals.
Oral LD50 - rat: >5000 mg/kg
Dermal LD50 - rabbit: >5000 mg/kg
Skin irritation - rabbit: practically non-irritating
Eye Irritation - rabbit:
not irritating (EEC Classification) moderately irritating (US Classification)
Inhalation LC50 - rat: >5.14 mg/L for 4 hr
Carcinogenicity:: A two-year feeding study of mancozeb indicated thyroid