THIRD AMENDMENT TO LEASE AGREEMENT
This Third Amendment to Lease Agreement (this “Third Amendment”) is made as of November 30, 2007, by and between
ARE-2425/2400/2450 GARCIA BAYSHORE, LLC, a Delaware limited liability company (“ Landlord ”), and MAP
PHARMACEUTICALS, INC. , a Delaware corporation (“ Tenant ”).
A. Landlord and Tenant entered into that certain Lease Agreement dated June 10, 2004, as amended by that certain First
Amendment to Lease Agreement dated August 2, 2004, and as amended by that certain Second Amendment to Lease
Agreement dated July 26, 2006 (as amended, the “Lease”), pursuant to which Landlord leased to Tenant certain premises
consisting of 32,116 square feet (“ Premises ”) located at 2400 Bayshore Parkway, Mountain View, California. Capitalized terms
used herein without definition shall have the meanings defined for such terms in the Lease.
B. Tenant has requested that Landlord’s remove certain casework and fume hoods from 2 labs on the first floor of the
Premises which work is more particularly described on Exhibit A attached hereto (“ Landlord’s Alteration Work ”).
C. Landlord and Tenant have agreed, subject to the terms and conditions set forth below, to amend the Lease to, among
other things, (i) provide for Landlord to undertake Landlord’s Alteration Work, and (ii) require Tenant to pay to Landlord
$30,898 to reimburse Landlord for the costs of Landlord’s Alteration Work and costs which Landlord may incur in connection
with restoring Landlord’s Alteration Work following the expiration or earlier termination of the Term,
NOW, THEREFORE, in consideration of the foregoing Recitals, which are incorporated herein by this reference, the mutual
promises and conditions contained herein, and for other good and valuable consideration, the receipt and sufficiency of which
are hereby acknowledged, Landlord and Tenant hereby agree as follows:
1. Landlord’s Alteration Work . Landlord hereby agrees to complete Landlord’s Alteration Work in