Security Agreement (this “ Agreement ”), dated as of October 30, 2007, between Hana
Biosciences Inc. (“ Obligor ”) in favor of Deerfield Private Design Fund, L.P., Deerfield Special
Situations Fund L.P., Deerfield Special Situations Fund International Limited and Deerfield Private
Design International, L.P (together, the “ Secured Party ”).
W I T N E S S E T H:
WHEREAS , Obligor has entered into a Facility Agreement, dated as of the date hereof (the “ Facility
Agreement ”), with the Secured Party;
NOW, THEREFORE , in consideration of the mutual agreements set forth herein, Obligor and the
Secured Party agree as follows:
1. Grant of Security Interest .
To secure payment and performance of the Obligations (as defined below), Obligor hereby
grants to Secured Party a security interest in all property and interests in property of Obligor, whether now
owned or hereafter acquired or existing, and wherever located (together with all other collateral security for the
Obligations at any time granted to or held or acquired by Secured Party, collectively, the “ Collateral ”),
including, without limitation, the following:
all General Intangibles;
all Investment Property ; and
all proceeds and products of (i), (ii), (iii), (iv) (v) and (vi).
Notwithstanding anything to the contrary contained in Section 1(a) above, the types or items of
Collateral described in such Section 1(a) shall not include any right or interest in any contract, permit or
application covering real or personal property of Obligor, as such, if under the terms of such contract, permit or
application or applicable law with respect thereto, the valid grant of a security interest to Secured Party is
prohibited as a matter of law or under the terms thereof and such prohibition has not been or is not waived or the
consent of the other party to such contrac