LOAN AND SECURITY AGREEMENT
This modification made this 8th day of March, 2001 to the Loan and Security Agreement ("Agreement") effective
June 10, 1999, as amended, between OSTEOTECH, INC., a Delaware Corporation; OSTEOTECH
INVESTMENT CORPORATION, a New Jersey Corporation; CAM IMPLANTS, INC., a Colorado
Corporation; OSTEOTECH, B.V., H.C.
IMPLANTS, B.V., CAM IMPLANTS, B.V., OSTEOTECH/CAM SERVICES, B.V., each a Company of
The Netherlands; and OST DEVELOPPEMENT, a Corporation of France (jointly and severally "Borrower")
and FLEET NATIONAL BANK, Successor in Interest to Summit Bank ("Lender") and to which Agreement
these presents are so firmly affixed as to become a part thereof.
Notwithstanding anything to the contrary set forth in the Agreement, the Agreement is hereby amended as
1. Section 1.1 is hereby amended to read as follows:
1.1(a) Lender agrees to provide, at one time or from time to time, at the request of the Borrower, loans to
Osteotech, Inc. in an aggregate amount up to Five Million Dollars ($5,000,000.00) on a revolving loan basis
("Loan I") for the purpose of working capital and capital expenditures and costs related to the construction of an
approximate 65,000 square foot addition (the "Project") to real property and improvements located at 201
Industrial Way West, Eatontown, New Jersey (the "Property"). Loan I is to be payable on the earlier of (i) May
31, 2002 or (ii) upon a Default.
1.1(b) In the absence of Default, the Borrower has the option to extend the term of Loan I for an additional four
(4) year term commencing on May 31, 2002, exercisable by written notice to Lender, not less than thirty (30)
days prior thereto. If such option is so exercised, the outstanding balance of Loan I becomes repayable in forty-
eight (48) equal monthly installments of principal, together with accrued interest.
2. Section 1.3(a) is hereby amended to read as follows:
1.3(a) Lender agrees to provide to Borrower loans in an aggregat