Antimicrobial and antioxidant activities of Cortex Magnoliae
Officinalis and some other medicinal plants commonly used in
Lai Wah Chan1, Emily LC Cheah1, Constance LL Saw2, Wanyu Weng1 and
Paul WS Heng*1
Address: 1Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117543 and 2Center for
Cancer Prevention Research, Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, State University of New Jersey, 160
Frelinghuysen Road, Piscataway, New Jersey 08854, USA
Email: Lai Wah Chan - firstname.lastname@example.org; Emily LC Cheah - email@example.com; Constance LL Saw - firstname.lastname@example.org;
Wanyu Weng - email@example.com; Paul WS Heng* - firstname.lastname@example.org
* Corresponding author
Background: Eight medicinal plants were tested for their antimicrobial and antioxidant activities.
Different extraction methods were also tested for their effects on the bioactivities of the medicinal
Methods: Eight plants, namely Herba Polygonis Hydropiperis (Laliaocao), Folium Murraya Koenigii
(Jialiye), Rhizoma Arachis Hypogea (Huashenggen), Herba Houttuyniae (Yuxingcao), Epipremnum
pinnatum (Pashulong), Rhizoma Typhonium Flagelliforme (Laoshuyu), Cortex Magnoliae Officinalis
(Houpo) and Rhizoma Imperatae (Baimaogen) were investigated for their potential antimicrobial and
Results: Extracts of Cortex Magnoliae Officinalis had the strongest activities against M. Smegmatis,
C. albicans, B. subtilis and S. aureus. Boiled extracts of Cortex Magnoliae Officinalis, Folium Murraya
Koenigii, Herba Polygonis Hydropiperis and Herba Houttuyniae demonstrated greater antioxidant
activities than other tested medicinal plants.
Conclusion: Among the eight tested medicinal plants, Cortex Magnoliae Officinalis showed the
highest antimicrobial and antioxidant activities. Different methods of extraction yield different
spectra of bioactivities.