PERSPECTIVES TINSZOO
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9 Percz.Reyes, E. et al. (1990) I. RIoI. C~I~III. 265,20430-20436
17 Soon& T.W. et al. (19941 Sot. Neurorcf. Abstr. 20,70
10 Dlmbaumer, L. et al. (1994) Ne~rrorl 13, SOS-506
18 Randall, A.D. and Tslen, R.W. /. Neurosclettce (In press)
11 OlIvera, D.M. et al. (1994) AMU. Rev. Bloc/re~~. 63,823~A67
19 Soon& T.W. et al. (1993) S&rice 260, 1133-1136
12 Catterall, W.A. and Strlessnlg, J. (1992) Trcrrds banrmcol.
20 Elllnor, P.T. et al. (1994) Nature 372,272-275
Sri. 13,256-262
21 PI gnell, M.E. et al, (1994) Nature 368,67-70
13 Wllllams, M.E. et al. (1992) Srlurrcc 257, 389-395
22 Westenbroek, R.E. et al. (1992) Neuron 9, 1099-1115
14 Fullta, Y. et al. (1993) Newmrr 10, 5R5
23 ArtcleJo, C.R. et aI0 (1990) N&rre 348,239-242
15 LllnBs, R. et al. (1992) Trends Nnrro.wf. 15, 351-355
24 Bennett, M., Calakos, N. and Schellcr, R.H. (1992) Sc&ce
16 Mlntz, LM. et RI. (1992) Nntrrru 355, 827-829
257,255-259
emories of NMDA receptors and LTP
G,L, Collingridge and T.VJ? Bliss
Trcrr& Nctrrosrl. (1995) 18, 54-56
INS,
T
UPON whose pages may all blessings fall, has
been enthuslastlc about long-term potentlatlon
(LTP) from the beglnnlng, publlshlng a review of
synaptic plastlclty In the hlppocampus soon after Its
Inauguration’, and another three years later’. It must,
therefore, accept some rcsponslblllty for fostering the
endurlng popularity of thls fasclnatlng phenomenon.
From 1973, when the first pair of papers on LTP
appeared In the /o~rnrrfl
o/‘Wtyslolo~y~‘~~,
publlcatlons on
LTP Increased exponentially, doubllng In number
approximately every three years to reach over 145 In
1992, [In the past two years, the rate of Increase has
declined, the baton of exponentlallty havlng passed
to Its slbllng, long-term depresslon (LTD)].
Despltc all this