SECOND AMENDMENT TO
CONVERTIBLE SECURED PROMISSORY NOTE
THIS SECOND AMENDMENT TO CONVERTIBLE SECURED PROMISSORY NOTE (the "Second
Amendment") is made and entered into as of April 12, 2005, by and among NORTHWEST
BIOTHERAPEUTICS, INC., a Delaware corporation (the "Maker") and ____________ (the "Holder"). This
Amendment amends the Note (as defined below).
A. Section 10 of that certain Convertible Secured Promissory Note, dated as of November 12, 2003 and
amended on April 26, 2004, by and between the Maker and the Holder (the "Note"), states that any provision of
such note may be amended or waived in writing by the Holder and the Maker; and
B. The Maker and the Holder wish to amend the Note as provided below.
NOW, THEREFORE, in consideration of these premises and for other good and valuable consideration, the
receipt and sufficiency of which are hereby acknowledged, the parties hereto agree as follows:
1. Section 1 of the Note is hereby amended and restated in its entirety as follows:
"1. Maturity Date. The aggregate principal amount of this Note and accrued interest thereon shall be due and
payable on July 12, 2005 (the "Maturity Date")."
2. All other terms and conditions of the Note shall be unaffected hereby and remain in full force and effect.
3. This Second Amendment shall be governed by and construed under the laws of the state of Washington as
applied to agreements among Washington residents entered into and to be performed entirely within the State of
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IN WITNESS WHEREOF, the parties hereto have executed this SECOND AMENDMENT TO
CONVERTIBLE SECURED PROMISSORY NOTE as of the date first above written.
NORTHWEST BIOTHERAPEUTICS, INC.,
a Delaware corporation
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