*Edited by Barbara J. Meyer. Last revised October 5, 2005. Published December 29, 2005. This chapter should be cited as: Haag, E. S. The
evolution of nematode sex determination: C. elegans as a reference point for comparative biology (December 29, 2005), WormBook, ed. The C.
elegans Research Community, WormBook, doi/10.1895/wormbook.1.120.1, http://www.wormbook.org.
Copyright: © 2005 Eric S. Haag. This is an open-access article distributed under the terms of the Creative Commons Attribution License,
which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
§To whom correspondence should be addressed. E-mail: ehaag@umd.edu
The evolution of nematode sex
determination: C. elegans as a
reference point for comparative
biology*
Eric S. Haag§, Department of Biology, University of Maryland, College
Park, MD 20742 USA
Table of Contents
1. Introduction ............................................................................................................................ 2
2. Genetic and environmental sex determination in nematodes ............................................................. 2
3. Deep conservation and cooption in the evolution of nematode sex determination ................................. 3
4. Conservation of C. elegans pathway components: C. briggsae as the ruler .......................................... 5
5. Two cases of species-specific genes ............................................................................................ 7
6. Comparative functional studies ................................................................................................... 7
7. Mating system evolution in Caenorhabditis .................................................................................. 7
8. Acknowledgements .................................................................................................................. 9
9. References ................................................................................