<p>Ethoxyfluorouracil
Safety Data Sheet
1. Product and Company Identification
Product name
Ethoxyfluorouracil
Product code
04 2019 0
Manufacturer:
F. Hoffmann-La Roche AG
Postfach
CH-4070 Basel
Switzerland
Phone
*41-61/688 54 80
Fax
*41-61/681 72 76
Local representation:
Company information
2. Composition/Information on ingredients
Chemical name
- 2-Ethoxy-5-fluoro-4(1H)-pyrimidinone
CAS number
56177-80-1
EINECS number
260 029 1
Roche number
Ro 07-5597/000
Empirical formula
C6H7FN2O2
Molecular mass
158.13 g/mol
N
N
H
O
O
F
3. Hazards identification
Most important hazards
- May cause cancer.
- May cause heritable genetic damage.
- May cause harm to the unborn child.
Note
- Cytostatics in general have to be classified as potentially
carcinogenic, teratogenic and mutagenic. During handling any
occupational exposure as well as environmental contamination have
to be avoided.
Page: 1/5
Replacing edition of:
26.3.98
Date: 12.7.02/CSE (SEISMO)
Ethoxyfluorouracil
4. First-aid measures
Eye contact
- rinse immediately with tap water for 10 minutes - open eyelids
forcibly
- consult physician
Skin contact
- remove immediately contaminated clothes, wash affected skin with
water and soap - do not use any solvents
Inhalation
- remove the casualty to fresh air
- consult physician
Note to physician
- treat symptomatically
- after massive exposition control of hemogram every 2 - 3 days for
2 - 3 weeks
5. Fire-fighting measures
Suitable extinguishing media
- water spray jet, dry powder, foam, carbon dioxide
Specific hazards
- formation of toxic and corrosive combustion gases (hydrogen
fluoride, nitrogen oxides) possible
Protection of fire-fighters
- precipitate gases/vapours/mists with water spray
- use self-contained breathing apparatus
Special method of fire-fighting
- cool endangered containers with water spray
6. Accidental release measures
Personal precautions
- keep people away and stay on the upwind side
Environmental protection
- avoid release to the environment
Methods for cleaning up
- collect solids (avoid dust