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<p>2015 ANNUAL REPORT
Our ability to interact with the world around us arises from
electrical impulses moving rapidly in coordinated patterns
in our brains. The pathways that underlie cognition are in
near constant flux, with neurons rapidly changing shape and
genetic program to process signals, create new connections
and adapt to our changing environment.
At the Allen Institute, our science reflects that same adaptive
motion. Building on the unique tools we created in our first
decade, we now study how neuronal signatures drive the
movement of signals between the brain’s more than 86 billion
neurons as they function in real time. We are revealing the
inner workings of our body’s cells as they mature. We are
analyzing and modeling our data in three dimensions. We
are interacting across disciplines and fields to develop new
technologies, integrate large-scale datasets and move into
a deeper understanding of our internal and external worlds.
A saggital view of the
mouse forebrain from
our mouse anatomic
The human brain would be complex enough if it
stood still. But each of its billions of cells are in near
constant motion, chattering over synapses and
reaching to form new connections. The elaborate
machinery of our brains drives who we are and what
makes us human. In our quest to understand the
brain, we are increasingly focused on deciphering
its parts and how they work and move together.
It has been an exceptional year at the Allen Institute.
In May, the Allen Institute for Brain Science debuted
a brand new product — the Allen Cell Types Database
— which puts a powerful tool to study and catalog the
cells of the brain in the hands of researchers around
the world. This past December, we were thrilled to
announce the launch of the Allen Institute for Cell
Science to create and share dynamic and predictive
three-dimensional models of cells, with an eye toward
changing the way we conduct biomedical research.
All of this m