Enzyme Terminox

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PRODUCT MATERIAL ENZYME TERMINOX ULTRA sensitive LIQUID Brenntag Canada respiratory sensitive
<p>MATERIAL SAFETY DATA SHEET
ENZYME TERMINOX ULTRA 50 L, LIQUID
3. HAZARDS IDENTIFICATION
Harmful if inhaled. Inhalation of enzyme dust or aerosols resulting from inappropriate handling may 
induce respiratory sensitization and may cause allergic reactions in sensitized individuals. See "Other 
Health Effects" Section. Can decompose at high temperatures forming toxic gases. Contents may 
develop pressure on prolonged exposure to heat.
EMERGENCY OVERVIEW:
POTENTIAL HEALTH EFFECTS
Inhalation of enzyme aerosol by susceptible individuals may result in allergic sensitization. May cause 
shortness of breath, wheezing, coughing and sneezing. May cause respiratory sensitization or other 
allergic responses. See Section 11, "Other Studies Relevant to Material".
Inhalation:
Prolonged, confined (especially under the finger nails, under rings or watch bands) or repeated exposure 
may cause skin irritation.
Skin Contact:
A single, prolonged skin exposure is not likely to result in the absorption of toxic amounts of the material.
Skin Absorption:
EMERGENCY TELEPHONE NUMBERS (FOR EMERGENCIES INVOLVING CHEMICAL SPILLS OR RELEASE)
Toronto, ON  (416) 226-6117                     Montreal, QC (514) 861-1211                     Winnipeg, MB (204) 943-8827
Edmonton, AB (780) 424-1754                  Calgary, AB  (403) 263-8660                       Vancouver, BC (604) 685-5036
1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
Brenntag Canada Inc.
43 Jutland Rd.
Toronto, ON
M8Z 2G6
(416) 259-8231
Website:  http:\\www.brenntag.ca
WHMIS#:
00065932
Index: 
2007 October 01
PRODUCT IDENTIFICATION
Enzyme Terminox Ultra 50 L, Liquid.
Product Name:  
2009 April 06
Date of Revision:
Effective Date:
HCI5072/09B
Aqueous mixture of catalase and 1,2-Benzisothiazol-3(2H)-one.
Chemical Name:
Not available.
Synonyms:
Enzyme Preparation (Protein).
Chemical Family:
Not applicable.
Molecular Formula:
Food additive. Food processing aid. Catalyst. Industrial application.
Product Use:
WHMIS Classification / Symbol:
READ THE ENTIRE MSDS FOR THE COMPLETE HAZARD EVALUATION OF THIS PRODUCT.
D-2A:  Very Toxic (respiratory sensitizer)
Ingredient
CAS#
ACGIH TLV
% Concentration
2. COMPOSITION, INFORMATION ON INGREDIENTS (Not Intended As Specifications)
Catalase
9001-05-2
--- 
< 15
1,2 - Benziso-thiazol-3 (2H) - one
2634-33-5
 
< 15
Enzyme Terminox Ultra 50 L, Liquid
Brenntag Canada Inc.
Date of Revision:
2009 April 06
WHMIS Number :
00065932
Page 2 of 7
4. FIRST AID MEASURES
FIRST AID PROCEDURES
Move victim to fresh air.  Give artificial respiration ONLY if breathing has stopped.  Give cardiopulmonary 
resuscitation (CPR) if there is no breathing AND no pulse.  Obtain medical attention IMMEDIATELY.
Inhalation:
Start flushing while removing contaminated clothing. Wash affected areas thoroughly with soap and 
water. If irritation, redness, or a burning sensation develops and persists, repeat flushing and obtain 
medical attention.
Skin Contact:
Immediately flush eyes with running water for a minimum of 20 minutes.  Hold eyelids open during 
flushing.  If irritation persists, repeat flushing.  Obtain medical attention IMMEDIATELY.
Eye Contact:
Do not attempt to give anything by mouth to an unconscious person. If victim is alert and not convulsing, 
rinse mouth out and give 1/2 to 1 glass of water to dilute material.  IMMEDIATELY contact local Poison 
Control Centre.  Vomiting should only be induced under the direction of a physician or a poison control 
centre.  If spontaneous vomiting occurs, have victim lean forward with head down to avoid breathing in of 
vomitus, rinse mouth and administer more water.  IMMEDIATELY transport victim to an emergency 
facility.
Ingestion:
Medical supervision of all employees who handle or come in contact with respiratory sensitizers is 
recommended.  This should include preemployment and periodic medical examinations with respiratory 
function tests (forced expiratory volume, forced vital capacity as a minimum).  Persons with asthmatic-
type conditions, chronic bronchitis, other chronic respiratory diseases or recurrent skin eczema or 
sensitization should be excluded from working with this product.  Once a person is diagnosed as 
sensitized, no further exposure to any sensitizer should be permitted.
Medical conditions that may be aggravated by exposure to this product include allergies to enzyme 
proteins ( asthma ).
Note to Physicians:
This product may cause irritation.
Eye Contact:
Ingestion of large amounts may cause nausea, gastrointestinal upset and abdominal pain.
Ingestion:
Effects (irritancy) on the skin and eyes may be delayed, and damage may occur without the sensation or 
onset of pain.  Strict adherence to first aid measures following any exposure is essential.
Other Health Effects:
5. FIRE-FIGHTING MEASURES
Flashpoint (°C)
AutoIgnition 
Temperature (°C)
LEL
UEL
Flammability Limits in Air (%):  
Not available.
Not available.
Not available.
Not available.
Not regulated.
Flammability Class (WHMIS):
Thermal decomposition products are toxic and may include oxides of carbon.
Hazardous Combustion 
Products:
Closed containers exposed to heat may explode. Spilled material may cause floors and contact surfaces 
to become slippery. Not normally a fire hazard.  Water content of product prevents ignition.  The product 
can support combustion if water evaporates.
Unusual Fire or Explosion 
Hazards:
Not expected to be sensitive to mechanical impact.
Sensitivity to Mechanical Impact:
Not available.
Rate of Burning:
Not available.
Explosive Power:
Not expected to be sensitive to static discharge.
Sensitivity to Static Discharge:
EXTINGUISHING MEDIA
Use media appropriate for surrounding fire and/or materials.
Fire Extinguishing Media:
FIRE FIGHTING 
INSTRUCTIONS
Use water spray to cool fire-exposed containers or structures.  Use water spray to disperse vapours. 
Spilled material may cause floors and contact surfaces to become slippery.
Instructions to the Fire Fighters:
Use self-contained breathing apparatus and protective clothing.
Fire Fighting Protective 
Equipment:
Enzyme Terminox Ultra 50 L, Liquid
Brenntag Canada Inc.
Date of Revision:
2009 April 06
WHMIS Number :
00065932
Page 3 of 7
6. ACCIDENTAL RELEASE MEASURES
Information in this section is for responding to spills, leaks or releases in order to prevent or minimize the adverse effects on persons, 
property and the environment.  There may be specific reporting requirements associated with spills, leaks or releases, which change from 
region to region.
In all cases of leak or spill contact vendor at Emergency Number shown on the front page of this MSDS. 
Spilled preparation should be removed immediately to avoid formation of dust from dried preparation. 
Take up by a mechanical means preferably by a vacuum cleaner equipped with a high efficiency filter. 
Avoid formation of aerosols.  Avoid splashing and high pressure washing. Wear protective clothing. 
Collect product for recovery or disposal.  For release to land, or storm water runoff, contain discharge by 
constructing dykes or applying inert absorbent;  for release to water, utilize damming and/or water 
diversion to minimize the spread of contamination.  Ventilate enclosed spaces.  Notify applicable 
government authority if release is reportable or could adversely affect the environment.
Containment and Clean-Up 
Procedures:
7. HANDLING AND STORAGE
HANDLING
Use normal "good" industrial hygiene and housekeeping practices. Containers exposed to heat may be 
under internal pressure.  These should be cooled and carefully vented before opening.  A face shield 
and apron should be worn. Follow Good Manufacturing Practices (GMP) when handling or storing this 
product.
Inhalation of enzyme dust or aerosols resulting from inappropriate handling may induce respiratory 
sensitization and may cause allergic reactions in sensitized individuals.
Handling Practices:
See Section 8, "Engineering Controls".
Ventilation Requirements:
Use only with adequate ventilation and avoid breathing vapours and aerosols. Avoid contact with eyes, 
skin or clothing.  Wash thoroughly with soap and water after handling.  Wash contaminated clothing 
thoroughly before re-use. Do not use cutting or welding torches on empty drums that contained this 
material/product.
Other Precautions:
STORAGE
Ideal storage temperature is 5 to 10 °C. Do not freeze.
Storage Temperature (°C):
General exhaust is acceptable.
Ventilation Requirements:
Do not expose sealed containers to temperatures above 40 Deg. Celsius.  Storage above 40 Deg. 
Celsius will see diminishment of product quality. Avoid moisture contamination. Protect from direct 
sunlight. Protect against physical damage. The typical shelf life of this product is 3 months. (3)
Storage Requirements:
Confirm suitability of any material before using.
Special Materials to be Used for 
Packaging or Containers:
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Recommendations listed in this section indicate the type of equipment, which will provide protection against overexposure to this product.  
Conditions of use, adequacy of engineering or other control measures, and actual exposures will dictate the need for specific protective 
devices at your workplace.
ENGINEERING CONTROLS
Local exhaust ventilation required. Make up air should be supplied to balance air that is removed by local 
or general exhaust ventilation. Ventilate low lying areas such as sumps or pits where dense vapours may 
collect.
Engineering Controls:
PERSONAL PROTECTIVE 
EQUIPMENT (PPE)
Safety glasses with side shields are recommended to prevent eye contact. Use chemical safety goggles 
when there is potential for eye contact. Contact lenses should not be worn when working with this 
material.
Eye Protection:
Gloves and protective clothing made from PVC or rubber or plastic should be impervious under 
conditions of use.   Prior to use, user should confirm impermeability. Discard contaminated gloves.
Skin Protection:
Enzyme Terminox Ultra 50 L, Liquid
Brenntag Canada Inc.
Date of Revision:
2009 April 06
WHMIS Number :
00065932
Page 4 of 7
No specific guidelines available. A NIOSH/MSHA-approved air-purifying respirator equipped with mist or 
aerosol cartridges for concentrations up to 100 ppm organic vapours. An air-supplied respirator if 
concentrations are higher or unknown.
If while wearing a respiratory protection, you can smell, taste or otherwise detect anything unusual, or in 
the case of a full facepiece respirator you experience eye irritation, leave the area immediately.  Check to 
make sure the respirator to face seal is still good.  If it is, replace the filter, cartridge or canister.  If the 
seal is no longer good, you may need a new respirator.  (4)
Respiratory Protection:
Wear an impermeable apron and boots. Locate safety shower and eyewash station close to chemical 
handling area. Take all precautions to avoid personal contact.
Other Personal Protective 
Equipment:
None established for this product.
EXPOSURE GUIDELINES
Liquid.
Amber brown liquid.
Typical fermentation odour.
Not available.
Not available.
Not available.
Not available.
Not available.
Not available.
Not available.
Not available.
Not available.
Soluble in water.
Not available.
Not available.
Not available.
Not available.
Physical State:
Appearance:
Odour:
Odour Threshold (ppm):
Boiling Range (°C):
Melting/Freezing Point (°C):
Vapour Pressure (mm Hg at 20° C):
Vapour Density (Air = 1.0):
Relative Density (g/cc):
Bulk Density:
Viscosity:
Evaporation Rate (Butyl Acetate = 1.0):
Solubility:
% Volatile by Volume:
pH:
Coefficient of Water/Oil Distribution:
Volatile Organic Compounds (VOC):
9. PHYSICAL AND CHEMICAL PROPERTIES  (Not intended as Specifications)
Not available.
Flashpoint (°C):
11. TOXICOLOGICAL INFORMATION
TOXICOLOGICAL DATA:
SUBSTANCE
LD50 (Oral, Rat)
LD50 (Dermal, Rabbit)
LC50 (Inhalation, Rat, 4h)
Catalase
>  2 000 mg/kg (3)
--- 
--- 
10. STABILITY AND REACTIVITY
CHEMICAL STABILITY
Stable.
Under Normal Conditions:
Not flammable.
Under Fire Conditions:
Will not occur.
Hazardous Polymerization:
High temperatures, sparks, open flames and all other sources of ignition. Do not store in humid places. 
Avoid direct sunlight.
Conditions to Avoid:
Strong oxidizers. Lewis or mineral acids. Strong bases.
Materials to Avoid:
Thermal decomposition products are toxic and may include oxides of carbon.
Decomposition or Combustion 
Products:
Enzyme Terminox Ultra 50 L, Liquid
Brenntag Canada Inc.
Date of Revision:
2009 April 06
WHMIS Number :
00065932
Page 5 of 7
1,2 - Benziso-thiazol-3 (2H) - 
one
1 020 mg/kg (1)
--- 
--- 
The ingredient(s) of this product is (are) not classed as carcinogenic by ACGIH, IARC, OSHA or NTP.
Carcinogenicity Data:
No adverse reproductive effects are anticipated.
Reproductive Data:
No adverse mutagenic effects are anticipated.
Mutagenicity Data:
No adverse teratogenic effects are anticipated.
Teratogenicity Data:
This product may cause respiratory sensitization or other allergic responses. Sensitization is the process 
whereby a biological change occurs in the individual because of previous exposure to a substance and, 
as a result, the individual reacts more strongly when subsequently exposed to the substance.  Once 
sensitized, an individual can react to extremely low airborne levels, even below the TLV, or to skin 
contact. See Section 11, "Other Studies Relevant to Material".
Respiratory / Skin Sensitization 
Data:
None known.
Synergistic Materials:
Inhalation of enzyme aerosol by susceptible individuals may result in allergic sensitization. Symptoms, 
which can be delayed by up to twelve hours after exposure, may include hay fever-like reactions such as 
runny eyes and nose, cough, chest tightness and shortness of breath. (3)
Other Studies Relevant to 
Material:
12. ECOLOGICAL INFORMATION
Low acute toxicity to aquatic organisms.
LC50 (Fish)    = Above 100 mg/L (3)     
EC50 (Daphnia) = Above 100 mg/L (3)
Ecotoxicity:
This product is biodegradable. Do not contaminate domestic or irrigation water supplies, lakes, streams, 
ponds, or rivers.
Environmental Fate:
13. DISPOSAL CONSIDERATIONS
Not available.
Deactivating Chemicals:
This information applies to the material as manufactured. Reevaluation of the product may be required 
by the user at the time of disposal since the product uses, transformations, mixtures and processes may 
influence waste classification. Dispose of waste material at an approved (hazardous) waste 
treatment/disposal facility in accordance with applicable local, provincial and federal regulations.  Do not 
dispose of waste with normal garbage, or to sewer systems.
Waste Disposal Methods:
See "Waste Disposal Methods".
Safe Handling of Residues:
Empty containers retain product residue and can be hazardous. Treat package in the same manner as 
the product.
Disposal of Packaging:
14. TRANSPORTATION INFORMATION
CANADIAN TDG ACT SHIPPING DESCRIPTION:
This product is not regulated by TDG.
Label(s):  Not applicable.          Placard:  Not applicable.
ERAP Index: -----.
Exemptions: None known.
US DOT CLASSIFICATION (49CFR 172.101, 172.102):
This product is not regulated by DOT.
Label(s):  Not applicable.          Placard:  Not applicable.
CERCLA-RQ: Not available.
Exemptions: None known.
15. REGULATORY INFORMATION
CANADA
Not available.
CEPA - NSNR:
Not included.
CEPA - NPRI:
Enzyme Terminox Ultra 50 L, Liquid
Brenntag Canada Inc.
Date of Revision:
2009 April 06
WHMIS Number :
00065932
Page 6 of 7
The use of this material/product as a food additive is regulated by Health and Welfare Canada in the 
Food and Drug Act and the Food and Drug Regulations.  It is incumbent on the user of this 
material/product to ensure any intended food application is consistent with Health and Welfare Canada 
guidelines. Food Grade designation in no way implies that the product is safe for consumption by 
humans.  (3)
CANADIAN FOOD AND DRUG 
ACT/REGULATIONS:
Controlled Products Regulations Classification (WHMIS):
16.  OTHER INFORMATION
REFERENCES
RTECS-Registry of Toxic Effects of Chemical Substances, Canadian Centre for Occupational Health and Safety RTECS 
database.
1.
Clayton, G.D. and Clayton, F.E., Eds., Patty's Industrial Hygiene and Toxicology, 3rd ed., Vol. IIA,B,C, John Wiley and Sons, New 
York, 1981.
2.
Supplier's Material Safety Data Sheet(s).
3.
CHEMINFO, through "CCINFOdisc", Canadian Centre for Occupational Health and Safety, Hamilton, Ontario, Canada.
4.
Guide to Occupational Exposure Values, 2007, American Conference of Governmental Industrial Hygienists, Cincinnati, 2007.
5.
Regulatory Affairs Group, Brenntag Canada Inc.
6.
The British Columbia Drug and Poison Information Centre, Poison Managements Manual, Canadian Pharmaceutical Association, 
Ottawa, 1981.
7.
____________________________________________________________________________________________________________
The information contained herein is offered only as a guide to the handling of this specific material and has been prepared in good faith by 
technically knowledgeable personnel.  It is not intended to be all-inclusive and the manner and conditions of use and handling may involve 
other and additional considerations.  No warranty of any kind is given or implied and Brenntag Canada Inc. will not be liable for any 
damages, losses, injuries or consequential damages which may result from the use of or reliance on any information contained herein.  
This Material Safety Data Sheet is valid for three years.
____________________________________________________________________________________________________________
To obtain revised copies of this or other Material Safety Data Sheets, contact your nearest Brenntag Canada Regional office.
British Columbia:  20333-102B Avenue, Langley, BC, V1M 3H1
         Phone:  (604) 513-9009         Facsimile:  (604) 513-9010
Alberta:   6628 - 45 th. Street, Leduc, AB, T9E 7C9
         Phone:  (780) 986-4544         Facsimile:  (780) 986-1070
Manitoba:  681 Plinquet Street, Winnipeg, MB, R2J 2X2
         Phone:  (204) 233-3416         Facsimile:  (204) 233-7005
Ontario:  43 Jutland Road, Toronto, ON, M8Z 2G6
         Phone:  (416) 259-8231         Facsimile:  (416) 259-5333
Quebec:  2900 Jean Baptiste Des., Lachine, PQ, H8T 1C8
         Phone:  (514) 636-9230         Facsimile:  (514) 636-0877
Atlantic:  A-105 Akerley Boulevard, Dartmouth, NS, B3B 1R7
         Phone:  (902) 468-9690         Facsimile:  (902) 468-3085
____________________________________________________________________________________________________________
USA
All constituents of this product are included on the TSCA inventory.
Environmental Protection Act:
Respiratory Sensitizer.
OSHA HCS (29CFR 1910.1200):
This material/product is regulated for use by the US FDA.  It is incumbent on the user of this 
material/product to ensure any intended food application is consistent with US FDA guidelines. Food 
Grade designation in no way implies that the product is safe for consumption by humans.  (3)
U.S. FOOD AND DRUG 
ADMINISTRATION:
Text22:
NFPA:  1 Health,   1 Fire,   0 Reactivity   (3)
Text22:
HMIS:  1 Health,   1 Fire,   0 Reactivity   (3)
INTERNATIONAL
Not available.
D-2A:  Very Toxic (respiratory sensitizer)
Enzyme Terminox Ultra 50 L, Liquid
Brenntag Canada Inc.
Date of Revision:
2009 April 06
WHMIS Number :
00065932
Page 7 of 7
Prepared By:  Regulatory Affairs Group, Brenntag Canada Inc., (416) 259-8231.
</p>