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1. Synonyms Total Iron Binding Capicity Flexreagent cartridge Dimension clinical chemistry system Flex reagent cartridge TIBC Validation Date 29 March 2005 DF83 Product Code In Case of Emergency Dimension system TIBC Flex reagent cartridge Product Trade Name Dade Behring Inc. P. O. Box 6101 Newark DE 19714 USA Product information: 800-441-9250 Manufactured/ Supplied Diagnostic Agents. Product Use Product and Company Identification Dimension system TIBC Flex reagent cartridge Material Safety Data Sheet MSDS No. DEDM0016 Transportation: (800) 424-9300 (CHEMTREC) Medical: (800) 228-5635 ext. 284 (Prosar) Composition and Information on Ingredients Reagent Water 99 7732-18-5 Not applicable. - - Acetamide, 2-chloro 0.3 79-07-2 Not applicable. T R25, R43, R62 Buffer solution Water 68 7732-18-5 Not applicable. - - Sodium acetate 14 127-09-3 Not applicable. - - Acetic acid 11 64-19-7 UN2789 C R10, R35 Polyoxyethylene octyl phenol ether (Triton) 7 9002-93-1 Not applicable. - - Urea, 2-thio 1.43 62-56-6 UN2877 Xn, N R22, R40, R51/53, R63 Ascorbic acid tablet L-Ascorbic acid 95 50-81-7 Not applicable. - Polyethylene glycol 5 25322-68-3 Not applicable. - - Ingredient Name CAS No. R-Phrases 2. Conc. (% w/w) EU Symbol U.N. No. Note: See section 8 for occupational exposure limits and section 11 for LC50/LD50 information. Hazards Identification 3. Primary Hazards and Critical Effects : DANGER! CAUSES RESPIRATORY TRACT, EYE AND SKIN BURNS. HARMFUL IF SWALLOWED. MAY CAUSE SEVERE ALLERGIC SKIN REACTION. CONTAINS MATERIAL WHICH MAY CAUSE CANCER CONTAINS MATERIAL WHICH CAUSES DAMAGE TO THE FOLLOWING ORGANS: BLOOD, KIDNEYS, NERVOUS SYSTEM, LIVER, HEART, BLADDER, SKIN, EYES., . Dimension system TIBC Flex reagent cartridge Page: 2/5 If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention immediately. Eye Contact Skin Contact In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention immediately. In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Get medical attention immediately. First Aid Measures 4. Ingestion Inhalation If inhaled, remove to fresh air. If not breathing, give artificial respiration. Get medical attention immediately. : : : : Fire-Fighting Measures 5. Fire-fighters should wear positive pressure self-contained breathing apparatus (SCBA) and full turnout gear. Hazardous Decomposition Products Fire/Explosion Hazards None identified. None identified. Fire-Fighting Procedures Use foam or all purpose dry chemicals to extinguish. : : : : Extinguishing Media Environmental Precautions and Clean-up Methods Personal Precautions Absorb with an inert material and put the spilled material in an appropriate waste disposal. Put on appropriate personal protective equipment (see Section 8). 6. Accidental Release Measures Note: See section 1 for emergency contact information and section 13 for waste disposal. : : Handling Handling and Storage Storage 7. Risk of cancer depends on duration and level of exposure. Do not get in eyes, on skin or on clothing. Do not ingest. Do not breathe vapor or mist. Avoid prolonged or repeated contact with skin. Keep container closed. Use only with adequate ventilation. Wash thoroughly after handling. : : Store in a segregated and approved area. Keep container in a cool, well-ventilated area. Keep container tightly closed and sealed until ready for use. Engineering Controls Good general ventilation should be sufficient to control airborne levels. 8. Exposure Controls and Personal Protection : Acetic acid ACGIH TLV (United States, 2003). STEL: 37 mg/m3 15 minute(s). STEL: 15 ppm 15 minute(s). TWA: 25 mg/m3 8 hour(s). TWA: 10 ppm 8 hour(s). NIOSH REL (United States, 2001). STEL: 37 mg/m3 15 minute(s). STEL: 15 ppm 15 minute(s). TWA: 25 mg/m3 10 hour(s). TWA: 10 ppm 10 hour(s). OSHA PEL (United States, 1993). TWA: 25 mg/m3 8 hour(s). TWA: 10 ppm 8 hour(s). OSHA PEL 1989 (United States, 1989). TWA: 25 mg/m3 8 hour(s). TWA: 10 ppm 8 hour(s). Not available. Polyethylene glycol AIHA WEEL (United States, 2001). TWA: 10 mg/m3 8 hour(s). Form: Aerosol Not available. Thiourea Not available. Not available. Ingredient Name OEL United States Occupational Exposure Limits OEL Canada Dimension system TIBC Flex reagent cartridge Page: 3/5 Skin and Body Personal Protective Equipment A respirator is not needed under normal and intended conditions of product use. : Additional body garments should be used based upon the task being performed (e.g., sleevelets, apron, gauntlets, disposable suits) to avoid exposed skin surfaces. : : Hands Safety glasses. Goggles, face shield, or other full-face protection if potential exists for direct exposure to aerosols or splashes. : Eyes Respiratory System Gloves. Physical and Chemical Properties Physical State and Appearance Melting Point Vapor Pressure Density Vapor Density Solubility Solid and Liquid. May start to solidify at 16.67C (62F) based on data for: Acetic acid. Weighted average: 1.65C (35F) Weighted average: 1.01 g/cm3 The highest known value is 2.1 (Air = 1) (Acetic acid). The highest known value is 2.4 kPa (18 mm Hg) (at 20C) (Water). Weighted average: 2.31 kPa (17.33 mm Hg) (at 20C) Easily soluble in cold water, hot water. Soluble in methanol. Partially soluble in diethyl ether, acetone. pH Evaporation Rate 1.34 (Acetic acid) compared to Butyl acetate. 9. : : : : : : : Acidic. : Viscosity Dynamic: The highest known value is 1.22 cP (Acetic acid) : Specific Gravity : Weighted average: 1.24 (Water = 1) Hazardous Decomposition Products Conditions and Materials to Avoid Highly reactive with oxidizing agents. Reactive with metals, acids, alkalis. Stability and Reactivity None identified. The product is stable. Stability 10. : : : Toxicological Information 11. Ingredient Name Water LD50 90000 mg/kg Oral Rat L-Ascorbic acid LD50 LD50 11900 mg/kg 3367 mg/kg Oral Oral Rat Mouse Sodium acetate LD50 LD50 3530 mg/kg 6891 mg/kg Oral Oral Rat. Mouse Acetic acid LD50 LD50 LDLo LDLo LC50 LC50 3300 mg/kg 1100 mg/kg 308 mg/kg 600 mg/kg 5620 (1 hours) 5000 (1 hours) Oral Dermal Oral Oral INHALATION INHALATION Rat Rabbit Male Rabbit Mouse Guinea pig Triton X-165 LD50 LD50 LD50 1900 mg/kg 3800 mg/kg 3800 mg/kg Oral Oral Oral rat rat Rat Polyethylene glycol LD50 LD50 LD50 LD50 31000 mg/kg 27500 mg/kg 17300 mg/kg >20000 mg/kg Oral Oral Oral Dermal Mouse Rat Rabbit Rabbit Thiourea LD50 LDLo LDLo 125 mg/kg 6985 mg/kg 1000 mg/kg Oral Oral Oral Rat Rabbit Mammal Species Route Result Test Toxicity Data Dimension system TIBC Flex reagent cartridge Page: 4/5 Acute Effects Eye Contact Corrosive to the eyes. Corrosive to the skin. May cause sensitization by skin contact. Skin Contact Contains material which causes damage to the following organs: blood, kidneys, the nervous system, liver, heart, bladder, upper respiratory tract, skin, eye, Target Organs Carcinogenic Effects Classified 2B (Possible for human.) by IARC, 3 (Possible for human.) by European Union [Urea, 2-thio]. Classified 2 (Reasonably Anticipated To Be Human Carcinogens.) by NTP [Urea, 2-thio]. Inhalation Ingestion 2-Chloroacetamide LD50 LD50 LD50 155 mg/kg 31 mg/kg 122 mg/kg Oral Oral Oral Mouse Dog Rabbit Harmful if swallowed. Corrosive to the respiratory system. Chronic Effects : : : : Adverse Effects : allergic reaction Routes of Entry Absorbed through skin. Dermal contact. Eye contact. Inhalation. : : : Ecological Information 12. Sodium acetate Bluegill. 24 hours 5000 ppm Acetic acid Minnow. (EC50) Lepomis macrochirus (LC50) Pimephales promelas (LC50) Pimephales promelas (LC50) 1 hours 96 hours 96 hours 96 hours >315 mg/l 75 mg/l 79 mg/l 88 mg/l Triton X-165 Pimephales promelas (LC50) Pimephales promelas (LC50) Pimephales promelas (LC50) Lepomis macrochirus (LC50) Lepomis macrochirus (LC50) Lepomis macrochirus (LC50) 96 hours 96 hours 96 hours 96 hours 96 hours 96 hours 4.5 mg/l 5.38 mg/l 6 mg/l >10 mg/l 12 mg/l 531 mg/l Polyethylene glycol Oncorhynchus mykiss (LC50) 96 hours >20000 mg/l Species Period Result Ecotoxicity Data Environmental Hazards No known significant effects or critical hazards. : Ingredient Name Disposal Consideration 13. Waste Handling and Disposal Waste must be disposed of in accordance with federal, state and local environmental control regulations. : Transport Information 14. Canada Sea Air Shipping Description Not regulated. : Shipping Description : Not regulated. Shipping Description Not regulated. : Remarks : - Shipping Description Not regulated. : Remarks : - United States Dimension system TIBC Flex reagent cartridge Page: 5/5 Regulatory Information 15. US Regulations Irritating material Sensitizing material Can cause cancer State WARNING: This product contains chemical(s) known to the State of California to cause cancer, birth defects or other reproductive harm: Urea, 2-thio Pennsylvania RTK: Acetic acid: (environmental hazard); Urea, 2-thio: (special hazard) Florida: Acetic acid Minnesota: Acetic acid; poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-; Urea, 2-thio Michigan critical material: Urea, 2-thio Massachusetts RTK: Acetic acid; Urea, 2-thio Massachusetts spill list: Urea, 2-thio New Jersey: Acetic acid; Polyoxyethylene octyl phenol ether; Urea, 2-thio TSCA 8(a) PAIR: Polyoxyethylene octyl phenol ether TSCA 8(b) inventory: Water; L-Ascorbic acid; Acetic acid, sodium salt; Acetic acid; Polyoxyethylene octyl phenol ether; poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.- hydroxy-; Urea, 2-thio; Acetamide, 2-chloro TSCA 8(d) H and S data reporting: Acetic acid SARA 302/304/311/312 hazardous chemicals: L-Ascorbic acid; Acetic acid, sodium salt; Acetic acid; Polyoxyethylene octyl phenol ether; Urea, 2-thio; Acetamide, 2-chloro SARA 311/312 MSDS distribution - chemical inventory - hazard identification: L-Ascorbic acid: Delayed (Chronic) Health Hazard; Acetic acid, sodium salt: Immediate (Acute) Health Hazard; Acetic acid: Fire hazard, Immediate (Acute) Health Hazard, Delayed (Chronic) Health Hazard; Polyoxyethylene octyl phenol ether: Immediate (Acute) Health Hazard, Delayed (Chronic) Health Hazard; Urea, 2-thio: Immediate (Acute) Health Hazard, Delayed (Chronic) Health Hazard; Acetamide, 2-chloro: Immediate (Acute) Health Hazard, Delayed (Chronic) Health Hazard SARA 313 toxic chemical notification and release reporting: Urea, 2-thio 1.43% CERCLA: Hazardous substances.: Acetic acid: 5000 lbs. (2268 kg); Urea, 2-thio: 10 lbs. (4.536 kg); Clean air act (CAA) 112 regulated toxic substances: Acetic acid, sodium salt Clean Water Act (CWA) 311: Acetic acid Haz-Com Standard EPA : : : Canadian Regulations WHMIS Provincial : : : Not a WHMIS controlled material. CEPA DSL: Water; L-Ascorbic acid; Acetic acid, sodium salt; Acetic acid; Polyoxyethylene octyl phenol ether; poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-; Urea, 2-thio; Acetamide, 2-chloro No products were found. CEPA Other Information 3/29/2005. 16. : Date of Printing 1.4 : Version To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist. Notice to Reader Validated by baldwinron on 3/29/2005.
