Ethyl Trifluoroacetate
ACETIC ACID, TRIFLUORO-, ETHYL ESTER
3088
1802050
5/20/2008.
5/20/2008.
Material Safety Data Sheet
Product name
Synonym
Manufacturer
Product No.
MSDS #
Validation date
Print date
In case of emergency
Product and company identification
Responsible name
MSDS (Regulatory Affairs)
Ethyl Trifluoroacetate
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1 .
Chemical formula
: C4-H5-F3-O2
CHEMTREC:
800.424.9300
OUTSIDE US:
202.483.7616
Supplier
: Thermo Fisher Scientific
Pierce Biotechnology
P.O. Box 117
Rockford, IL 61105
United States
815.968.0747 or
800.874.3723
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Use of
Substance/Preparation
Refer to the instruction booklet for
proper and intended use.
Otherwise, contact supplier for
specific applications.
: Thermo Fisher Scientific
Pierce Biotechnology
P.O. Box 117
Rockford, IL 61105
United States
815.968.0747
800.874.3723
Ingestion.
Emergency overview
Hazards identification
Routes of entry
Potential acute health effects
Irritating to respiratory system.
Severely irritating to eyes. Risk of serious damage to eyes.
Harmful if swallowed.
Irritating to skin.
Eyes
Skin
Inhalation
Ingestion
Physical state
Liquid.
WARNING !
FLAMMABLE LIQUID AND VAPOR. CAUSES RESPIRATORY TRACT, EYE AND
SKIN IRRITATION. MAY BE HARMFUL IF SWALLOWED.
Flammable liquid. Harmful if swallowed. Severely irritating to eyes. Irritating to
respiratory system and skin. Keep away from heat, sparks and flame. Do not ingest.
Do not get in eyes. Avoid breathing vapor or mist. Avoid contact with skin and clothing.
Use only with adequate ventilation. Keep container tightly closed and sealed until ready
for use. Wash thoroughly after handling.
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OSHA/HCS status
: This material is considered hazardous by the OSHA Hazard Communication Standard
(29 CFR 1910.1200).
2 .
Potential chronic health effects
Carcinogenicity
: No known significant effects or critical hazards.
Mutagenicity
: No known significant effects or critical hazards.
Teratogenicity
: No known significant effects or critical hazards.
Developmental effects
: No known significant effects or critical hazards.
Chronic effects
: No known significant effects or critical hazards.
Fertility effects
: No known significant effects or critical hazards.
Over-exposure signs/symptoms
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Ethyl Trifluoroacetate
Hazards identification
2 .
See toxicological information (section 11)
Medical conditions
aggravated by over-
exposure
Pre-existing digestive disorders may be aggravated by over-exposure to this product.
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Ingestion
: No specific data.
Skin
: Adverse symptoms may include the following:
irritation
redness
Eyes
: Adverse symptoms may include the following:
pain or irritation
watering
redness
Inhalation
: Adverse symptoms may include the following:
respiratory tract irritation
coughing
The substance is classified as dangerous according to Directive 67/548/EEC and its amendments.
Classification
F; R11
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Physical/chemical hazards
: Highly flammable.
Ethyl Trifluoroacetate
383-63-1
98 - 100
Composition/information on ingredients
Name
CAS number
%
United States
3 .
There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and
in the concentrations applicable, are classified as hazardous to health or the environment and hence require
reporting in this section.
Substance/preparation
Substance
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Wash out mouth with water. Remove dentures if any. Move exposed person to fresh
air. Keep person warm and at rest. If material has been swallowed and the exposed
person is conscious, give small quantities of water to drink. Stop if the exposed person
feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do
so by medical personnel. If vomiting occurs, the head should be kept low so that vomit
does not enter the lungs. Get medical attention. Never give anything by mouth to an
unconscious person. If unconscious, place in recovery position and get medical
attention immediately. Maintain an open airway. Loosen tight clothing such as a collar,
tie, belt or waistband.
Flush contaminated skin with plenty of water. Remove contaminated clothing and
shoes. Continue to rinse for at least 10 minutes. Get medical attention. Wash clothing
before reuse. Clean shoes thoroughly before reuse.
Move exposed person to fresh air. If it is suspected that fumes are still present, the
rescuer should wear an appropriate mask or self-contained breathing apparatus. Keep
person warm and at rest. If not breathing, if breathing is irregular or if respiratory arrest
occurs, provide artificial respiration or oxygen by trained personnel. It may be dangerous
to the person providing aid to give mouth-to-mouth resuscitation. Get medical attention.
If unconscious, place in recovery position and get medical attention immediately.
Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband.
First aid measures
Skin contact
Inhalation
Ingestion
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Ethyl Trifluoroacetate
First aid measures
4 .
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting
the upper and lower eyelids. Check for and remove any contact lenses. Get medical
attention. Chemical burns must be treated promptly by a physician.
Eye contact
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Protection of first-aiders
: No action shall be taken involving any personal risk or without suitable training. If it is
suspected that fumes are still present, the rescuer should wear an appropriate mask or
self-contained breathing apparatus. It may be dangerous to the person providing aid to
give mouth-to-mouth resuscitation.
See section 11 for more detailed information on health effects and symptoms.
Use dry chemical, CO2, water spray (fog) or foam.
Fire-fighting measures
Extinguishing media
Promptly isolate the scene by removing all persons from the vicinity of the incident if
there is a fire. No action shall be taken involving any personal risk or without suitable
training. Move containers from fire area if this can be done without risk. Use water
spray to keep fire-exposed containers cool.
Flammable liquid. In a fire or if heated, a pressure increase will occur and the container
may burst, with the risk of a subsequent explosion. Runoff to sewer may create fire or
explosion hazard.
Special protective
equipment for fire-fighters
Fire-fighters should wear appropriate protective equipment and self-contained breathing
apparatus (SCBA) with a full face-piece operated in positive pressure mode.
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Special exposure hazards
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Do not use water jet.
Suitable
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Not suitable
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Hazardous combustion
products
: Decomposition products may include the following materials:
carbon oxides
halogenated compounds
Flammability of the product
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No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
entering. Do not touch or walk through spilled material. Shut off all ignition sources. No
flares, smoking or flames in hazard area. Avoid breathing vapor or mist. Provide
adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put
on appropriate personal protective equipment (see section 8).
Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash
spillages into an effluent treatment plant or proceed as follows. Contain and collect
spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or
diatomaceous earth and place in container for disposal according to local regulations
(see section 13). Use spark-proof tools and explosion-proof equipment. Dispose of via
a licensed waste disposal contractor. Contaminated absorbent material may pose the
same hazard as the spilled product. Note: see section 1 for emergency contact
information and section 13 for waste disposal.
Environmental precautions
Accidental release measures
: Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
Personal precautions
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Large spill
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Stop leak if without risk. Move containers from spill area. Dilute with water and mop up
if water-soluble or absorb with an inert dry material and place in an appropriate waste
disposal container. Use spark-proof tools and explosion-proof equipment. Dispose of
via a licensed waste disposal contractor.
Small spill
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Ethyl Trifluoroacetate
Store in accordance with local regulations. Store in a segregated and approved area.
Store in original container protected from direct sunlight in a dry, cool and well-ventilated
area, away from incompatible materials (see section 10) and food and drink. Eliminate
all ignition sources. Separate from oxidizing materials. Keep container tightly closed
and sealed until ready for use. Containers that have been opened must be carefully
resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use
appropriate containment to avoid environmental contamination.
Put on appropriate personal protective equipment (see section 8). Eating, drinking and
smoking should be prohibited in areas where this material is handled, stored and
processed. Workers should wash hands and face before eating, drinking and smoking.
Do not breathe vapor or mist. Do not ingest. Avoid contact with eyes, skin and clothing.
Use only with adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Do not enter storage areas and confined spaces unless adequately
ventilated. Keep in the original container or an approved alternative made from a
compatible material, kept tightly closed when not in use. Store and use away from heat,
sparks, open flame or any other ignition source. Use explosion-proof electrical
(ventilating, lighting and material handling) equipment. Use non-sparking tools. Take
precautionary measures against electrostatic discharges. To avoid fire or explosion,
dissipate static electricity during transfer by grounding and bonding containers and
equipment before transferring material. Empty containers retain product residue and
can be hazardous. Do not reuse container.
Handling and storage
Handling
Storage
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Exposure controls/personal protection
Use a properly fitted, air-purifying or air-fed respirator complying with an approved
standard if a risk assessment indicates this is necessary. Respirator selection must be
based on known or anticipated exposure levels, the hazards of the product and the safe
working limits of the selected respirator.
Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
Personal protective equipment for the body should be selected based on the task being
performed and the risks involved and should be approved by a specialist before handling
this product.
Personal protection
Eyes
Skin
Respiratory
Consult local authorities for acceptable exposure limits.
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Chemical-resistant, impervious gloves complying with an approved standard should be
worn at all times when handling chemical products if a risk assessment indicates this is
necessary.
Hands
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Engineering measures
: Use only with adequate ventilation. Use process enclosures, local exhaust ventilation or
other engineering controls to keep worker exposure to airborne contaminants below any
recommended or statutory limits. The engineering controls also need to keep gas, vapor
or dust concentrations below any lower explosive limits. Use explosion-proof ventilation
equipment.
Hygiene measures
: Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period. Appropriate
techniques should be used to remove potentially contaminated clothing. Wash
contaminated clothing before reusing. Ensure that eyewash stations and safety showers
are close to the workstation location.
Recommended monitoring
procedures
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If this product contains ingredients with exposure limits, personal, workplace atmosphere
or biological monitoring may be required to determine the effectiveness of the ventilation
or other control measures and/or the necessity to use respiratory protective equipment.
Europe
No exposure limit value known.
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Ethyl Trifluoroacetate
Exposure controls/personal protection
8 .
Environmental exposure
controls
: Emissions from ventilation or work process equipment should be checked to ensure they
comply with the requirements of environmental protection legislation. In some cases,
fume scrubbers, filters or engineering modifications to the process equipment will be
necessary to reduce emissions to acceptable levels.
61°C (141.8°F)
Liquid.
1.194
142.08 g/mole
Clear. Colorless.
Boiling/condensation point
Physical and chemical properties
Physical state
Molecular weight
Relative density
Color
C4-H5-F3-O2
Molecular formula
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Flash point
: Open cup: -1.1111°C (30°F)
9 .
The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
Reactive or incompatible with the following materials: oxidizing materials
Will not occur.
Under normal conditions of storage and use, hazardous decomposition products should
not be produced.
Avoid all possible sources of ignition (spark or flame). Do not pressurize, cut, weld,
braze, solder, drill, grind or expose containers to heat or sources of ignition.
Stability and reactivity
Chemical stability
Conditions to avoid
Incompatible materials
Hazardous decomposition
products
Possibility of hazardous
reactions
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10 .
Toxicological information
United States
11 .
Acute toxicity
Conclusion/Summary
: To the best of our knowledge, the toxicological properties of this substance have not
been thoroughly investigated.
Chronic toxicity
Conclusion/Summary
: Not available.
Carcinogenicity
Conclusion/Summary
: Not available.
Mutagenicity
Conclusion/Summary
: Not available.
Teratogenicity
Conclusion/Summary
: Not available.
Reproductive toxicity
No known significant effects or critical hazards.
Chronic effects
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No known significant effects or critical hazards.
Carcinogenicity
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No known significant effects or critical hazards.
Mutagenicity
No known significant effects or critical hazards.
Teratogenicity
Developmental effects
: No known significant effects or critical hazards.
Fertility effects
: No known significant effects or critical hazards.
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Europe
Not available.
Conclusion/Summary
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Ethyl Trifluoroacetate
Ecological information
United States
Environmental effects
: No known significant effects or critical hazards.
12 .
Aquatic ecotoxicity
Conclusion/Summary
: Not available.
The generation of waste should be avoided or minimized wherever possible. Dispose of
surplus and non-recyclable products via a licensed waste disposal contractor. Disposal
of this product, solutions and any by-products should at all times comply with the
requirements of environmental protection and waste disposal legislation and any regional
local authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
Waste disposal
Disposal considerations
Disposal should be in accordance with applicable regional, national and local laws and regulations.
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13 .
Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
for additional handling information and protection of employees.
Hazardous waste
: The classification of the product may meet the criteria for a hazardous waste.
Transport information
3
DOT Classification
FLAMMABLE
LIQUIDS, N.O.S.
II
FLAMMABLE
LIQUIDS, N.O.S.
UN1993
IATA-DGR Class
3
Regulatory
information
UN number
Proper shipping
name
Classes
PG*
II
UN1993
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PG* : Packing group
Flammable liquid
Irritating material
HCS Classification
Regulatory information
U.S. Federal regulations
United States inventory (TSCA 8b): This material is listed or exempted.
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean Air Act (CAA) 112 accidental release prevention: No products were found.
Clean Air Act (CAA) 112 regulated flammable substances: No products were found.
Clean Air Act (CAA) 112 regulated toxic substances: No products were found.
CEPA Toxic substances: This material is not listed.
Canadian ARET: This material is not listed.
Canadian NPRI: This material is not listed.
Alberta Designated Substances: This material is not listed.
Ontario Designated Substances: This material is not listed.
Quebec Designated Substances: This material is not listed.
WHMIS (Canada)
Class B-2: Flammable liquid
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No
products were found.
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Canada
United States
15 .
Canadian lists
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Ethyl Trifluoroacetate
Regulatory information
15 .
Australia inventory (AICS): Not determined.
China inventory (IECSC): This material is listed or exempted.
Korea inventory (KECI): This material is listed or exempted.
Philippines inventory (PICCS): This material is listed or exempted.
Japan inventory (ENCS): This material is listed or exempted.
International regulations
International lists
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EU regulations
Canada inventory
: Canada inventory: This material is not listed in DSL but is listed in NDSL.
R11- Highly flammable.
Hazard symbol or symbols
Risk phrases
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Highly flammable
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Other information
Hazardous Material
Information System (U.S.A.)
2
3
0
0
3
2
National Fire Protection
Association (U.S.A.)
Health
Special
Instability
Flammability
Health
Flammability
Physical hazards
FLAMMABLE LIQUID AND VAPOR. CAUSES RESPIRATORY TRACT, EYE AND
SKIN IRRITATION. MAY BE HARMFUL IF SWALLOWED.
Label requirements
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Notice to reader
Date of printing
Date of issue
Date of previous issue
Version
5/20/2008.
5/20/2008.
1
No previous validation.
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16 .
The customer is responsible for determining the PPE code for this material.
Indicates information that has changed from previously issued version.
Full text of R-phrases
referred to in sections 2 and
3 - Europe
: R11- Highly flammable.
Full text of classifications
referred to in sections 2 and
3 - Europe
: F - Highly flammable
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Ethyl Trifluoroacetate
Other information
16 .
To the best of our knowledge, the information contained herein is accurate. However, neither the above-named
supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the
information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present
unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot
guarantee that these are the only hazards that exist.
This product has been classified according to the hazard criteria of the CPR and the MSDS contains all the information required by the CPR.
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