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<p>Manchester: Driving Research and Innovation Through Partnerships Manchester UK, has a wealth of world‑class research and innovation assets and is the country’s first fully devolved health and social care system with a budget of £6bn. Under the coordination of Health Innovation Manchester, the city offers unique opportunities to develop partnerships which deliver research and innovation at pace and scale. Devolution provides unique opportunities to improve the cost and quality of health care and transform health outcomes for nearly 3m residents. Health care is provided for free at the point of access for all UK residents by one provider, the National Health Service (NHS). All health care commissioning takes place locally offering businesses direct access to over 30 NHS service providers. Some of the city’s partnership strengths are: Health Analytics Manchester is a recognised world leader in health analytics. The city’s unique data ecosystem allows researchers to monitor consenting patients in real-time, making it the perfect location to gain real-world evidence for pre-license medicine and shorten time to market. The region was the base for the Salford Lung Study, a world first in real-world trials. The Salford Lung Study provided evidence for one drug being more effective than the current treatment of asthma. MedTech The region has a strong cluster of existing MedTech companies including Hologic and Premaitha Health. Research institutes such as the Manchester Molecular Pathology Innovation Centre (MMPathIC) work in partnership with both SMEs and global corporates to refine the development pathway for diagnostics and translate discoveries into tests. Manchester is the home of the first commercial mass spectrometers and is now a world leader in this field with a dedicated research centre, the Michael Barber Centre for Mass Spectrometry. The city also offers opportunities to explore the medical applications of advanced materials such as graphene. Precision Medicine Manchester has attracted around £96m in grant income in the past five years for precision medicine focused on, genomics, proteomics, imaging, and biomarkers. The city is home to The Manchester Precision Medicine Institute which allows a range of professionals to work with patients to personalise their care. The £18m Stoller Biomarker Discovery Centre is industrialising the approach to finding new biomarkers of diagnosis, prognosis and responses to therapy in medicine. Finally, the Manchester Centre for Genomic Medicine is one of the largest and most comprehensive genetics units in Europe. The unit develops new tests and supports the development of genetic services internationally. Our Talent Manchester is home to one of the largest student bodies in Europe, with a student population of almost 100,000 across the city’s four universities. There are also a further 19 universities within an hour’s drive time of the city. 70% of the UK’s clinical lab scientists are trained in Manchester, and Manchester Metropolitan University trains the majority of health professionals allied to medical science. Our Population Manchester has an ethnically diverse, stable population of almost 3m with a further 9m falling within Manchester’s health catchment area. The city’s population has a higher than average prevalence of long-term conditions such as diabetes, chronic obstructive pulmonary disease and heart disease. There is a determination from stakeholders throughout the city to improve health outcomes for the population by accelerating the adoption and diffusion of innovations into the health and social care system. Health Innovation Manchester has a world-leading set of partners including: The health analytics capabilities of the Health e Research Centre and Farr Institute ensures anonymised data becomes a rich source of information for clinicians and innovators. It is home to the coordinating centre for the UK’s Connected Health Cities project. The project enables four cities to share information to improve health outcomes. herc.ac.uk @HeRC_Farr The Northern Health Science Alliance (NHSA) is a single point of entry for health care industries interested in establishing biomedical research and innovation in the North of England. It brings together the North of England’s leading universities, NHS teaching hospitals and four Academic Health Science Networks in one health partnership. Uniting a 15m patient population, the NHSA can support industry in evaluating their new technology within the UK’s health provider, source academic or clinical partners for collaboration and support technology scouting across various institutions. thenhsa.co.uk @The_NHSA NorthWest EHealth is an industry leader in the area of health analytics and electronic health record clinical trials. The company provided the technology which enabled the success of the Salford Lung Study and are the only organisation in the world to have evaluated the safety and effectiveness of a pre-license medicine in a real-world setting. They work with consenting patients who provide their data from primary and secondary care, community pharmacies and other data sources to deliver validated electronic health record randomised controlled trials, safely and securely. nweh.co.uk @NWEHealth Bionow is a membership organisation focused on supporting and enhancing the growth and competitiveness of the life science cluster in the North of England. They are committed to providing high- quality services that add tangible value to members’ operational activity and growth prospects. Their members include biotech, pharmaceutical, health care and medical device companies, and the specialist supply chain. bionow.co.uk @Bionow TRUSTECH bridges the gap between the UK’s health care provider (the NHS), commissioners, and the commercial, academic and international health care sectors. Their aim is to improve the way in which the NHS operates by encouraging the development or adoption of innovative techniques, solutions, technologies and services for the benefit of all patients. TRUSTECH’s Innovation Nexus service is a gateway to holistic business growth support focused on the specialist needs of life science SMEs. They have worked with many international MedTech companies to help them develop and adapt their technologies for the UK market. trustech.org.uk @TRUSTECH_NHS Working Together to Deliver Innovation Manchester is home to an exceptional integrated infrastructure to speed up the delivery of health innovations to address unmet medical needs. These organisations provide invaluable support to businesses looking to bring innovation to Manchester, the North and the UK. Greater Manchester Health and Social Care Partnership (GMHSC) is responsible for the £6bn budget to improve the health of Manchester’s 3m citizens and achieve world- class service standards. The Partnership is committed to working with industry to maximise the role which industry-led innovation can play in improving health outcomes and reducing costs. gmhsc.org.uk @GM_HSC Health Innovation Manchester is the city regions academic health science network. Operating within a devolved health and social care system has enabled them to create a unique infrastructure and environment for industry innovators to flourish. They offer a single industry gateway and innovation pathway, world- class informatics infrastructure, clear view of system needs, and processes that enable speedier decision making and shorter and more certain routes to adoption. healthinnovationmanchester.com @healthinnovmcr Home to Four Thriving Universities Manchester’s four universities produce over 33,000 graduates per year of which 40% remain in the region. The universities are all proactively engaged in establishing collaboration opportunities with life science organisations globally. The University of Manchester is the UK's largest single-site university, ranks 34th in the QS World University Rankings and is a founder member of Health Innovation Manchester. The University undertakes multidisciplinary research through collaborations with partners worldwide to tackle some of society's most pressing problems. Home to over 2,000 researchers, the university’s size and scale enable unparalleled interdisciplinary inquiry. manchester.ac.uk @OfficialUoM Salford University attracts collaboration with global health and social care organisations and is constantly looking to develop relationships. Industry is able to access Salford’s state-of-the-art facilities such as their digital imaging suite, psychology labs, and prosthetics and orthotics lab. salford.ac.uk @SalfordUni Manchester Metropolitan University has a long and proud history of working with the very best health providers in the UK and abroad. Its ambition is to build on the expertise within the University and partnerships to make a positive impact, contributing to the future design, development and delivery of systemic health care outcomes which improve the health and wellbeing of individuals, families and communities. mmu.ac.uk @ManMetUni Bolton University’s Centre for Research in Health and Wellbeing provides research and public engagement to improve communities health and wellbeing. Research is based upon collaborative partnerships and community involvement. The team has expertise in evaluation, needs assessment, service user involvement, participation and innovation. bolton.ac.uk @BoltonUni Globally Connected Manchester has a wide variety of property, innovation and research assets connected to key life science hubs by Manchester Airport which flies direct to over 200 destinations. North America Atlanta 8hrs Boston 8hrs Chicago 9hrs 30 Houston 10hrs 20 Las Vegas 11hrs Los Angeles 12+hrs Miami 12+hrs New York 8hrs San Francisco 11hrs 20 Toronto 8hrs 30 Asia Pacific Beijing 12hrs Hong Kong 13hrs 15 Singapore 13hrs 20 Middle East Abu Dhabi 7hrs Cairo 5hrs 10 Dubai 7hrs 50 Tel Aviv 5hrs 20 Africa Cairo 5hrs 10 United Kingdom London 1h 5 Dublin 1h Europe Amsterdam 1h 25 Athens 3hrs 50 Barcelona 2hrs 30 Belfast 1h Berlin 1h 50 Copenhagen 1h 55 Helsinki 2hrs 40 Istanbul 4hrs 10 Madrid 2hrs 40 Munich 2hrs Paris 1h 30 Rome 2hrs 45 Stockholm 2hrs 25 Venice 2hrs 15 Zurich 1h 55 life sciences & allied subjects graduates 13,405 157,000 health & social care workforce 1 of 4 Health eResearch Centres forming the UK Farr Institute biomedical companies Home to 260+ Companies in the wider region include: health & social care budget £6bn to London 2 hours Direct flights to 200+ destinations including San Francisco and Boston England’s most successful clinical trial recruitment site Access to 20 million consumers within 2 hours’ drive. Home to the National Institute for Health and Care Excellence (NICE) foreign-owned companies 2,000+ life sciences & allied subjects graduates 13,405 157,000 health & social care workforce 1 of 4 Health eResearch Centres forming the UK Farr Institute biomedical companies Home to 260+ Companies in the wider region include: health & social care budget £6bn to London 2 hours Direct flights to 20+ destinations including San Francisco and Boston England’s most successful clincal trial recruitment site Access to 20 millon consumers within 2 hours’ drive. Home to the National Institute for Health and Care Excellence (NICE) foreign-owned companies 2,000+ lif i lli j t r t lt il r rfr lt r tr fr i t rr I tit i i l i t i i t i r r i i l : lt il r t t ir t fli t t 0 ti ti i l i r i t l ’ t fl li l tril r rit t it t illi r iti r’ ri . t t ti l I tit fr lt r ll ( I ) fri - i life sciences & allied subjects graduates 13,405 157,000 health & social care workforce 1 of 4 Health eResearch Centres forming the UK Farr Institute biomedical companies Home to 260+ Companies in the wider region include: health & social care budget £6bn to London 2 hours Direct flights to 200+ destinations including San Francisco and Boston England’s most successful clinical trial recruitment site Access to 20 million consumers within 2 hours’ drive. Home to the National Institute for Health and Care Excellence (NICE) foreign-owned companies 2,000+ life sciences & allied subjects graduates 13,405 157,000 health & social care workforce 1 of 4 Health eResearch Centres forming the UK Farr Institute biomedical companies Hme to 260+ Companies in the wider region include: health & social care budget £6bn to London 2 hours Direct flights to 200+ destinations including San Francisco and Boston England’s most uccessful clinical trial recruitment site Access to 20 million consumers within 2 hours’ drive. Home to the National Institute for Health and Care Excellence (NICE) foreign-owned companies 2,00+ Key Facts Corridor Manchester* Corridor Manchester is on course to become one of the top five innovation districts in Europe. It is home to a wealth of knowledge intensive organisations operating in a range of areas including health, higher education and advanced materials. The Corridor is also the site of the UK’s multi million pound ‘smart city’ Internet of Things technology demonstrator, CityVerve, which will deploy technologies that allow for rapid scalability and interoperability, and the virtualisation of data. corridormanchester.com | @corridormcr Manchester Science Partnerships (MSP)* MSP is home to a unique community of scientists, innovators, investors and entrepreneurs. By putting collaboration first and providing access to specialist finance, talent, markets, networks and investors, MSP is able to support the acceleration of business growth through innovation. As the UK’s leading science and technology park operator, MSP is home to more than 300 high growth businesses and offers everything from specialist incubation centers to bespoke build laboratories and international centers of R&D excellence. mspl.co.uk | @TweetsbyMSP *Companies located in the Enterprise Zone will benefit from business rate discounts, super-fast broadband and simplified planning procedures. Manchester Science Park £50million Citylabs £28.5million Total capital investment Central Manchester University Hopsital £50million University of Manchester £700million Manchester Metropolitian University £34million Brooks building Manchester Campus £139million Corridor Manchester Investment MediaCityUK An eclectic and exciting mix of over 200 businesses call MediaCityUK their home. From global celebrated brands like the BBC, ITV and Bupa to SMEs such as Now Healthcare, MediaCityUK combines all cross-sections of the digital creative industry to create a unique environment where SMEs and corporates can thrive. The Landing, a space specifically designed for SMEs, is home to initiatives such as PwC’s Future of Health Accelerator and Barclays Eagle Labs. mediacityuk.co.uk | @MediaCityUK Key Life Science Hubs Airport City* Airport City Manchester is one of the most exciting business destinations in development today. The total planning area of Airport City Manchester comprises of approximately 5m sq. ft. GFA, with a total development cost of £650m and value of £800m. The site encompasses offices, advanced manufacturing and logistics facilities, along with hotels and ancillary retail. Directly adjacent to Manchester Airport, it is perfectly positioned for business with the UK, Europe and the world. airportcity.co.uk | @AirportCityUK The Christie The Christie is renowned as a world pioneer in the care, treatment and research of cancer. The largest single-site cancer center in Europe, The Christie treats more than 44,000 patients a year and has one of the largest trial portfolios in the UK, with over 550 active clinical trials. christie.nhs.uk | @TheChristieNHS Trafford Park Trafford Park is the first purpose built industrial park in the world and with over 97m sq. ft. of business space, remains one of the largest and most successful business parks in Europe. Globally recognised as a centre of excellence, Trafford Park is home to over 1,330 businesses employing over 35,000 people. Kratos Analytical alongside Shimadzu’s European Research Laboratory are located here. investintrafford.com/BusinessLocations/ trafford‑park.aspx | @TraffordBiz Central Manchester University Hospitals NHS Foundation Trust (CMFT)* Home to five specialist hospitals, including the largest children’s hospital in the UK and a leading centre for genomic medicine, the trust is a leading provider of tertiary and specialist health care treating over a million patients a year. The Trust is also home to MSP’s Citylabs campus which is currently under expansion, enabling health and medical technology companies to grow and co-create new health products, in collaboration with the UK’s health care provider. cmft.nhs.uk | @CMFTNHS Hexagon Tower Hexagon Tower is a specialist science and technology facility. As a former ICI research, development and production centre, innovation is at the site’s core and the vertical science park is home to companies such as Lonza and Intertek. hexagon‑tower.co.uk | @HexagonTower Salford Royal NHS Group Salford Royal NHS Foundation Trust is England’s only fully e-enabled health trust placing it at the forefront of health informatics. The Trust formed the test bed of the world’s first large-scale, real-world clinical trial – The Salford Lung Study. srft.nhs.uk | @SalfordRoyalNHS The largest NHS cluster in the UK Manchester is home to a cluster of leading general and specialist hospitals including: HELLO Manchester is a service that offers free or discounted office space, professional services as well as preferential hotel and restaurant rates to overseas investors. This ‘soft landing’ initiative enables companies to establish a foothold in Europe’s top city for business competitiveness with minimal risk and cost. All of this is underpinned by a vibrant quality of life and complimentary business support from MIDAS. To find out more contact: info@midas.org.uk HELLO MANCHESTER *Companies located in the Enterprise Zone will benefit from business rate discounts, super-fast broadband and simplified planning procedures. </p>