In USA: In Europe: Thermo Fisher Scientific Perbio Science P.O. Box 117 Industriezone III Rockford, IL 61105 Industrielaan 27 USA 9320 Erembodegem-Aalst 815.968.0747 or Belgium 1.800.874.3723 Tel:+32 53 83 44 04 Fax:+32 53 83 76 38 Conforms to 93/112/EC and ISO 11014-1 Material Safety Data Sheet 16% Formaldehyde Solution 28906 28908 1892258 Product Name Supplier Manufacturer Product no. In case of emergency Section 1. Chemical Product and Company Identification Responsible Name MSDS Specialist Use of the substance/preparation Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications. Eng CHEMTREC: 800.424.9300 OUTSIDE US: 703.527.3887 Print date 2/28/2007 2/28/2007 Validation date MSDS# 7600 Pierce 3747 N. Meridian Road P.O. Box 117 Rockford, IL 61105 USA 815.968.0747 or 1.800.874.3723 (815)968-7316 fax www.thermo.com Substance/preparation Preparation : Section 2. Composition, Information on Ingredients CAS number Ingredient name % EC number Classification Formaldehyde 50-00-0 10 - 20 200-001-8 Carc. Cat. 3; R40 T; R23/24/25 C; R34 R43 Dermal contact. Eye contact. Inhalation. Ingestion. Emergency overview Section 3. Hazards identification Routes of entry Do not ingest. Avoid contact with eyes, skin and clothing. Do not breathe vapor or mist. Keep away from heat, sparks and flame. Keep container closed. Use only with adequate ventilation. Wash thoroughly after handling. Risk of cancer depends on duration and level of exposure. Review the most current and approved institutional guideline, protocol, standard operating procedure(s) and MSDS(s) for the proper handling of institutional materials/equipment associated with the use of this product. Warning! CANCER HAZARD CONTAINS MATERIAL WHICH CAN CAUSE CANCER HARMFUL IF INHALED, ABSORBED THROUGH SKIN OR SWALLOWED. CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION. MAY CAUSE ALLERGIC RESPIRATORY REACTION. COMBUSTIBLE LIQUID AND VAPOR. VAPOR MAY CAUSE FIRE. United States Potential acute health effects Toxic by inhalation. Irritating to respiratory system. May cause sensitization by inhalation. Irritating to eyes. Toxic if swallowed. Toxic in contact with skin. Irritating to skin. Eyes Skin Inhalation Ingestion Potential chronic health effects Continued on Next Page 16% Formaldehyde Solution Page: 2/8 Physical/chemical hazards Human health hazards Environmental hazards Not applicable. Harmful by inhalation, in contact with skin and if swallowed. Causes burns. Possible risk of irreversible effects. May cause sensitization by skin contact. Not applicable. Medical conditions aggravated by overexposure Repeated or prolonged contact with spray mist may produce chronic eye irritation and severe skin irritation. Repeated or prolonged exposure to spray mist may produce respiratory tract irritation leading to frequent attacks of bronchial infection. Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in one or many human organs. Not available. Over-exposure signs/symptoms Carcinogenic effects See toxicological Information (section 11) CARCINOGENIC EFFECTS: Classified 1 (Proven for human.) by IARC [formaldehyde]. Classified A2 (Suspected for human.) by ACGIH [formaldehyde]. MUTAGENIC EFFECTS: Classified SUSPECTED for human [formaldehyde]. Mutagenic for mammalian somatic cells. [formaldehyde]. Mutagenic for bacteria and/or yeast. [formaldehyde]. TERATOGENIC EFFECTS: Classified POSSIBLE for human [formaldehyde]. Classification Carc. Cat. 3; R40 Xn; R20/21/22 C; R34 R43 Europe Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention immediately. Skin contact Ingestion In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention immediately. In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention immediately. Inhalation of the spray mist may produce severe irritation of respiratory tract, characterized by coughing, choking, or shortness of breath. Over-exposure by inhalation may cause respiratory irritation. May be fatal if inhaled. May be fatal if swallowed. May cause burns to mouth, throat and stomach. Hazardous in case of skin contact (sensitizer). Slightly hazardous in case of skin contact (irritant). Corrosive to skin on contact. Skin contact may produce burns. Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering. Skin contact Slightly hazardous in case of eye contact (irritant). Corrosive to eyes. Eye contact Inhalation Aggravating conditions Repeated or prolonged contact with spray mist may produce chronic eye irritation and severe skin irritation. Repeated or prolonged exposure to spray mist may produce respiratory tract irritation leading to frequent attacks of bronchial infection. Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in one or many human organs. First-Aid measures If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention immediately. Notes to physician Not available. Not available. Protection of first-aiders Ingestion Effects and symptoms Inhalation Eye contact Section 4. First aid measures Notice to reader Get immediate medical attention. Combustible. Closed cup: >60°C (140°F). Use an extinguishing agent suitable for surrounding fires. Not available. Section 5. Fire fighting measures Flammability of the product Flash Points Fire hazards in presence of various substances Fire fighting media and instructions Continued on Next Page 16% Formaldehyde Solution Page: 3/8 Hazardous thermal decomposition products These products are carbon oxides (CO, CO2). Be sure to use an approved/certified respirator or equivalent. Protective clothing (fire) Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Absorb with DRY earth, sand or other non-combustible material. Do not get water inside container. Do not touch spilled material. Use water spray curtain to divert vapor drift. Prevent entry into sewers, basements or confined areas; dike if needed. Call for assistance on disposal. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system. Section 6. Accidental release measures Small spill and leak Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Environmental precautions and clean-up methods Personal precautions Face shield. Full suit. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Boots. Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not ingest. Do not get in eyes, on skin or on clothing. Keep container closed. Use only with adequate ventilation. Do not breathe vapor or mist. Wash thoroughly after handling. Section 7. Handling and storage Handling Storage Suitable / Not suitable Packaging materials Use original container. Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications. Czech Republic - Storage code III Formaldehyde ACGIH (United States). CEIL: 0.3 ppm NIOSH (United States). TWA: 0.016 ppm OSHA PEL (United States). TWA: 0.75 ppm STEL: 2 ppm United States Ingredient Name Occupational Exposure Limits Engineering Controls Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respective occupational exposure limits. Ensure that eyewash stations and safety showers are proximal to the work- station location. Section 8. Exposure Controls, Personal Protection Exposure Limit Values Formaldehyde NGV: 0.5 ppm TGV: 1 ppm Formaldehyde GV: 0.3 ppm Formaldehyde AN: 0.5 ppm Formaldehyde VME: 0.5 ppm VLE: 1 ppm Formaldehyde TGG: 1 ppm TGG 15 min: 2 ppm Sweden Denmark Norway France Netherlands Continued on Next Page 16% Formaldehyde Solution Page: 4/8 Boots. Personal Protection Eyes Body Hands Feet Protective Clothing (Pictograms) Gloves. Lab coat. Splash goggles. Respiratory Respirator is not needed under normal and intended conditions of use, if exposures are kept below established limits. Formaldehyde MAK: 0.5 ppm Germany Formaldehyde TWA: 1 ppm STEL: 2 ppm Belgium Formaldehyde MAK-W: 0.5 ppm KZG-W: 1 ppm Switzerland Formaldehyde MAK: 0.5 ppm Austria Formaldehyde TWA: 2 ppm United Kingdom (UK) Turkey Formaldehyde NIOSH (United States). TWA: 0.016 ppm >93.33°C (200°F) L i q u i d . ( C l e a r sparkling liquid.) Neutral. May start to solidify at 0°C (32°F) based on data for: water. 1.08 to 1.13 (Water = 1) 1 (Air = 1) 2.3 to 2.7 kPa (17 to 20 mm Hg) (at 20°C) See solubility in water, methanol, diethyl ether, acetone. Easily soluble in cold water, hot water, methanol, acetone. Partially soluble in diethyl ether. The lowest known value is 374.2°C (705.6°F) (water). Not applicable. Characteristic. (Slight.) Not available. Colorless. Boiling/condensation point Melting/freezing point >1 compared to Butyl acetate. Dynamic: The highest known value is 1 cP (water) Physical State Molecular weight pH (1% Soln/Water) Critical temperature Specific Gravity Vapor pressure Vapor density Evaporation rate Viscosity Dispersion properties Solubility Odor Taste Color Section 9. Physical and chemical properties Explosion limits Flash point Lower: 7% Upper: 73% Closed cup: >60°C (140°F). Continued on Next Page 16% Formaldehyde Solution Page: 5/8 The product is stable. Reactive with acids, alkalis. Will not occur. Not available. Section 10. Stability and reactivity Stability and Reactivity Conditions to avoid Materials to avoid Hazardous polymerization Hazardous Decomposition Products Not available. water: ORAL (LD50): Acute: >90000 mg/kg [ Rat]. formaldehyde: ORAL (LD50): Acute: 100 mg/kg [Rat]. 42 mg/kg [Mouse]. 260 mg/kg [Guinea pig]. DERMAL (LD50): Acute: 270 mg/kg [Rabbit]. GAS (LC50): Acute: 454 mg/m3 4 hour(s) [Mouse]. 505 mg/m3 2 hour(s) [Mouse]. 578 mg/m3 2 hour(s) [Rat]. 250 ppm 2 hour(s) [Rat]. Hazardous in case of eye contact (corrosive), of inhalation (lung corrosive). Slightly hazardous in case of eye contact (irritant), of inhalation (lung irritant). CARCINOGENIC EFFECTS: Classified 1 (Proven for human.) by IARC [formaldehyde]. Classified A2 (Suspected for human.) by ACGIH [formaldehyde]. MUTAGENIC EFFECTS: Classified SUSPECTED for human [formaldehyde]. Mutagenic for mammalian somatic cells. [formaldehyde]. Mutagenic for bacteria and/or yeast. [formaldehyde]. TERATOGENIC EFFECTS: Classified POSSIBLE for human [formaldehyde]. Not available. Not available. Not available. Section 11. Toxicological information Toxicity to Animals Chronic Effects on Humans Other Toxic Effects on Humans Special Remarks on Toxicity to Animals Special Remarks on Chronic Effects on Humans Special Remarks on Other Toxic Effects on Humans Skin Ingestion Inhalation No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. Over-exposure signs/symptoms Contains material which may cause cancer based on animal data. Risk of cancer depends on duration and level of exposure. Carcinogenicity No known significant effects or critical hazards. Mutagenicity No known significant effects or critical hazards. Reproductive toxicity Ecotoxicity Not available. Mobility Germany water class Not available. Not available. Not available. Persistence/degradability Bioaccumulative potential VCI WGK: No products were found. Section 12. Ecological information Species Period Result Ecotoxicity data Ingredient name Continued on Next Page 16% Formaldehyde Solution Page: 6/8 Mobility Not available. : Formaldehyde Minnows (LC50) Bluegill. (LC50) Daphnia (EC50) 96 hour(s) 96 hour(s) 96 hour(s) 24.1 mg/l 0.1 mg/l 20 mg/l LogPow BCF Persistence/degradability Bioaccumulative potential Other ecological information Other adverse effects : No known significant effects or critical hazards. Ingredient name Ingredient name BOD5 COD Ingredient name Aquatic half-life Photolysis Not available. Waste Stream Section 13. Disposal considerations Denmark – Carcinogenic waste Not available. Not available. Sweden - thermoset plastic waste Not available. European waste catalogue (EWC) The classification of the product may meet the criteria for a hazardous waste Hazardous waste Austria - Waste catalogue Not available. Denmark - Waste card number Not available. Denmark - Waste group Not available. Sweden - Waste group Not available. Norway - Waste number Not available. Switzerland - Waste code Not available. The generation of waste should be avoided or minimized wherever possible. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Methods of disposal Norway - Hazardous waste The classification of the product may meet the criteria for a hazardous waste Contact the supplier for all information regarding the proper transportation method for this material. Section 14. Transport information Section 15. Regulatory information R40- Limited evidence of a carcinogenic effect. R20/21/22- Harmful by inhalation, in contact with skin and if swallowed. R34- Causes burns. R43- May cause sensitization by skin contact. S2- Keep out of the reach of children. S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39- Wear suitable protective clothing, gloves and eye/face protection. S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). Label Requirements (Europe) 1 Continued on Next Page 16% Formaldehyde Solution Page: 7/8 U.S. Federal Regulations Combustible liquid Toxic material Irritating material Sensitizing material Carcinogen HCS Classification TSCA 8(b) inventory: 16% Formaldehyde Solution Clean Water Act (CWA) 307: No products were found. Clean Water Act (CWA) 311: No products were found. Clean air act (CAA) 112 accidental release prevention: No products were found. Clean air act (CAA) 112 regulated flammable substances: No products were found. Clean air act (CAA) 112 regulated toxic substances: No products were found. CEPA DSL: water; formaldehyde Australia (NICNAS): water Germany water class: formaldehyde Japan (METI): water Korea (TCCL): water Philippines (RA6969): water WHMIS (Canada) Class B-3: Combustible liquid with a flash point between 37.8°C (100°F) and 93.3°C (200°F). Class D-1A: Material causing immediate and serious toxic effects (VERY TOXIC). Class D-2A: Material causing other toxic effects (VERY TOXIC). Class D-2B: Material causing other toxic effects (TOXIC). R40- Limited evidence of a carcinogenic effect. R20/21/22- Harmful by inhalation, in contact with skin and if swallowed. R34- Causes burns. R43- May cause sensitization by skin contact. DSCL (EEC) International Regulations Not available. EINECS International Lists SARA 302/304/311/312 extremely hazardous substances: formaldehyde SARA 302/304 emergency planning and notification: formaldehyde SARA 302/304/311/312 hazardous chemicals: No products were found. SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found. Corrosive Illinois toxic substances disclosure to employee act: formaldehyde Illinois chemical safety act: formaldehyde New York release reporting list: formaldehyde Pennsylvania RTK: formaldehyde Minnesota: formaldehyde Massachusetts RTK: formaldehyde Massachusetts spill list: formaldehyde New Jersey: formaldehyde New Jersey spill list: formaldehyde Louisiana RTK reporting list: formaldehyde Louisiana spill reporting: formaldehyde State regulations SARA 313 Form R - Reporting requirements Formaldehyde 50-00-0 10 - 20 : Product name CAS number Concentration SARA 313 notifications must not be detached from the MSDS and any copying and redistribution of the MSDS shall include copying and redistribution of the notice attached to copies of the MSDS subsequently redistributed. Continued on Next Page 16% Formaldehyde Solution Page: 8/8 Illinois toxic substances disclosure to employee act: formaldehyde Illinois chemical safety act: formaldehyde New York release reporting list: formaldehyde Pennsylvania RTK: formaldehyde Minnesota: formaldehyde Massachusetts RTK: formaldehyde Massachusetts spill list: formaldehyde New Jersey: formaldehyde New Jersey spill list: formaldehyde Louisiana RTK reporting list: formaldehyde Louisiana spill reporting: formaldehyde State Regulations Version 1 Date of previous issue No Previous Validation Not available. Section 16. Other information References Validated by MSDS Specialist on 2/28/2007. Verified by MSDS Specialist. Printed 2/28/2007. Notice to reader To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist. Hazardous Material Information System (U.S.A.) National Fire Protection Association (U.S.A.) History of Document Changes Any information changes since last document version are marked with a triangle symbol. Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications. Full text of classifications referred to in sections 2 and 3 - Europe Full text of R phrases referred to in sections 2 and 3 - Europe Carc. Cat.3 - Carcinogen Category 3 T - Toxic C - Corrosive Xn - Harmful R40- Limited evidence of a carcinogenic effect. R23/24/25- Toxic by inhalation, in contact with skin and if swallowed. R20/21/22- Harmful by inhalation, in contact with skin and if swallowed. R34- Causes burns. R43- May cause sensitization by skin contact. 2 2 0 C * Health Fire hazard Reactivity Personal protection 0 2 2 Health Special Instability Flammability