Presented by Daniel Toriola
Asthma allergy is a prevalent medical condition that is characterized by breathlessness, tightness in the chest
area, coughing and wheezing. People who suffer from this condition can lead relatively normal lives if
appropriate measures are taken
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Exercise Induced Asthma
By Sakshi
Exercise Induced Asthma (EIA) or Exercise Induced Bronchospasm (EIB) refers to asthma that
occurs only with exercise. The reported incidence of EIA varies between 5% and 20% of the general
population.
During start of exercise pulmonary functions tends to be normal, but within 5 to 10 minutes symptoms
of asthma such as wheezing, breathlessness, tightness of chest appear. Patient may also feel extreme
fatigue. After a rest period, the symptoms subside. But sometimes symptoms may become worse for a
longer time.
Hyperventilation and airway cooling are the two most important triggers of EIA. People with exercise
induced asthma have airways that are sensitive towards changes of temperature and humidity.
Hyperventilation during exercise is the primary event which causes cascade of events leading to EIA.
Hyperventilation causes drying of the airway surface epithelium where by causing dehydration of the
airway cells and increased intracellular osmolarity. The increased osmolarity results in the release of
mediators from mast cells and damage airway epithelial. The mediators released during EIA include
histamine, leukotrienes, cytokines, etc. All these events are called inflammatory reaction which is the
root cause of asthma.
Other but less important cause of EIA is the airway cooling that is found with hyperventilation during
exercise. During rest we breath through nose. Nose has a temperature and humidity control
mechanism that makes air humid and at body temperature. W