Thrombocytopenia is defined as a platelet count that falls below its normal range. The normal value of platelets for an adult is 150000 to 450000 microliter. A platelet count of more than 450000 microliter is called thrombocytosis and a platelet count of less than 150000 microliter is called thrombocytopenia. Various types of thrombocytopenia occur based on theircause such as immune thrombocytopenic purpura, heparin induced thrombocytopenia, thrombotic thrombocytopenic purpura, immune thrombocytopenia, and drug induced thrombocytopenia. Various causes of thrombocytopenia are due to some of the drugs, diseases and disorders, chemical exposures, microorganisms, and some rare conditions that cause blood clots. The underlying pathophysiology of thrombocytopenia is decreased platelet production, increased platelet destruction, and platelets redistribution. The effective diagnosis and treatment may help the patient improve in their quality of life and help to achieve an optimal therapeutic outcome. The scope of this review is to describe thrombocytopenia, types, etiology, pathophysiology, diagnosis, pharmacological treatment, non pharmacological treatment, and its prevention. D. N. Ashritha | Subhashini. A | Dr. K. C. Arul Prakasam | Deborah Rose "A Review: Thrombocytopenia" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-6 , October 2021, URL: https://www.ijtsrd.com/papers/ijtsrd47659.pdf Paper URL : https://www.ijtsrd.com/pharmacy/other/47659/a-review-thrombocytopenia/d-n-ashritha
International Journal of Trend in Scientific Research and Development (IJTSRD)
Volume 5 Issue 6, September-October 2021 Available Online: www.ijtsrd.com e-ISSN: 2456 – 6470
@ IJTSRD | Unique Paper ID – IJTSRD47659 | Volume – 5 | Issue – 6 | Sep-Oct 2021
Page 1444
A Review: Thrombocytopenia
D. N. Ashritha, Subhashini. A, Dr. K. C. Arul Prakasam, Deborah Rose
Department of Pharmacy Practice, JKKMMRF’s Annai JKK
Sampoorani Ammal College of Pharmacy, Komarapalayam, Tamil Nadu, India
ABSTRACT
Thrombocytopenia is defined as a platelet count that falls below its
normal range. The normal value of platelets for an adult is 150000 to
450000/ microliter. A platelet count of more than 450000/microliter
is called thrombocytosis and a platelet count of less than
150000/microliter is called thrombocytopenia. Various types of
thrombocytopenia occur based on theircause such as immune
thrombocytopenic purpura, heparin-induced thrombocytopenia,
thrombotic thrombocytopenic purpura, immune thrombocytopenia,
and drug-induced
thrombocytopenia. Various
causes of
thrombocytopenia are due to some of the drugs, diseases and
disorders, chemical exposures, microorganisms, and some rare
conditions that cause blood clots. The underlying pathophysiology of
thrombocytopenia is decreased platelet production, increased platelet
destruction, and platelets redistribution. The effective diagnosis and
treatment may help the patient improve in their quality of life and
help to achieve an optimal therapeutic outcome. The scope of this
review is
to describe
thrombocytopenia,
types, etiology,
pathophysiology, diagnosis, pharmacological treatment, non-
pharmacological treatment, and its prevention.
KEY WORDS: Thrombocytopenia, Etiology, Types, Pathophysiology,
Sign and Symptoms, Diagnosis, Treatment
How to cite this paper: D. N. Ashritha |
Subhashini. A | Dr. K. C. Arul Prakasam
|
Deborah
Rose
"A Review:
Thrombocytopenia"
Published
in
International
Journal of Trend in
Scientific Researc